Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Angela Giorgianni"'
Exploring class III cellobiose dehydrogenase: sequence analysis and optimized recombinant expression
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-16 (2024)
Abstract Background Cellobiose dehydrogenase (CDH) is an extracellular fungal oxidoreductase with multiple functions in plant biomass degradation. Its primary function as an auxiliary enzyme of lytic polysaccharide monooxygenase (LPMO) facilitates th
Externí odkaz:
https://doaj.org/article/ed49b9e404144502b0c277a278454922
Publikováno v:
Chemical Research in Toxicology. 19:937-943
Etoposide is a widely used antineoplastic agent that has provided great success in the treatment of childhood leukemias and other malignancies. Unfortunately, its use is associated with the increased risk of development of secondary acute myelogenous
Autor:
Werner Ens, Yu Jiang, Jack C. Yalowich, Xing Wu, Tejomoortula Sivaram, Angela Giorgianni, Kenneth G. Standing, Shaohua Yang, Brian B. Hasinoff, John L. Nitiss, Oleg V. Krokhin
Publikováno v:
Molecular Pharmacology. 67:937-947
Cisplatin was shown to strongly inhibit the decatenation and relaxation activity of isolated human DNA topoisomerase IIalpha. This inhibition was not accompanied by stabilization of a covalent topoisomerase IIalpha-DNA intermediate. Pretreatment of k
Autor:
John S. Lazo, Jack C. Yalowich, Peter Wipf, Marni Brisson, Angela Giorgianni, Ivet Bahar, Corey R. J. Stephenson, Dror Tobi, Theresa Nguyen, Andreas Vogt
Publikováno v:
Molecular Pharmacology. 66:824-833
Cdc25A and Cdc25B dual-specificity phosphatases are key regulators of cell cycle transition and proliferation. They have oncogenic properties and are overexpressed in many human tumors. Because selective Cdc25 phosphatase inhibitors would be valuable
Autor:
Valerian E. Kagan, Julie P. Goff, Irina I. Vlasova, Jack C. Yalowich, Angela Giorgianni, Wei Hong Feng, Duc Do, Susanne M. Gollin, Dale W. Lewis
Publikováno v:
Molecular pharmacology. 79(3)
Etoposide is a widely used anticancer drug successfully used for the treatment of many types of cancer in children and adults. Its use, however, is associated with an increased risk of development of secondary acute myelogenous leukemia involving the
Publikováno v:
The FASEB Journal. 20
Publikováno v:
Chemical Research in Toxicology. 20:1067-1067