Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Angela G. Brittsan"'
Autor:
Albrecht Schmidt, Gerald W. Dorn, James W. Lester, Evangelia G. Kranias, Atsuko Yatani, Kobra Haghighi, Brian D. Hoit, Jing Zhai, David H. MacLennan, Yoshihiro Kimura, Angela G. Brittsan
Publikováno v:
Journal of Biological Chemistry. 276:24145-24152
To determine whether selective impairment of cardiac sarcoplasmic reticulum (SR) Ca(2+) transport may drive the progressive functional deterioration leading to heart failure, transgenic mice, overexpressing a phospholamban Val(49) --Gly mutant (2-fol
Publikováno v:
Journal of Biological Chemistry. 275:12129-12135
Phospholamban is a phosphoprotein in the cardiac sarcoplasmic reticulum (SR) which regulates the apparent Ca(2+) affinity of the SR Ca(2+)-ATPase (SERCA2). To determine the levels of phospholamban which are associated with maximal inhibition of SERCA
Autor:
Albrecht Schmidt, Michio Asahi, Kenneth S. Ginsburg, David H. MacLennan, Beata M. Wolska, Evangelia G. Kranias, Donald M. Bers, Atsuko Yatani, Guoxiang Chu, Angela G. Brittsan
Publikováno v:
Circulation research. 92(7)
Phospholamban, the critical regulator of the cardiac SERCA2a Ca 2+ affinity, is phosphorylated at Ser 16 and Thr 17 during β-adrenergic stimulation (eg, isoproterenol). To assess the impact of nonphosphorylatable phospholamban, a S16A, T17A double-m
Publikováno v:
Journal of molecular and cellular cardiology. 32(12)
Autor:
Evangelia G. Kranias, István Édes, Ingrid L. Grupp, Gunter Grupp, Eva Kiss, Angela G. Brittsan
Publikováno v:
Journal of molecular and cellular cardiology. 31(9)
The aim of the present study was to determine the effects of beta -adrenergic stimulation in wild-type and phospholamban-deficient mouse hearts with altered thyroid conditions. Hypothyroidism was associated with significant decreases in heart/body we
Autor:
Brian D. Hoi, Kobra Haghighi, Evangelia G. Kranias, Yoshihiro Kimura, David H. MacLennan, Angela G. Brittsan, Albrecht Schmidt
Publikováno v:
Journal of Cardiac Failure. 5:11
Publikováno v:
Journal of Cardiac Failure. 4:20