Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Angela Fu"'
Autor:
Wei Wang, MD, PhD, Liyan Zhang, PhD, Pavan K. Battiprolu, PhD, Arata Fukushima, MD, PhD, Khanh Nguyen, BS, Kenneth Milner, BS, Abhishek Gupta, PhD, Tariq Altamimi, PhD, Nikole Byrne, BS, Jun Mori, MD, PhD, Osama Abo Alrob, PhD, Cory Wagg, Natasha Fillmore, PhD, Shao-hua Wang, MD, PhD, Dongming M. Liu, BS, Angela Fu, BS, Jenny Yinglin Lu, BS, Mary Chaves, MS, Alykhan Motani, PhD, John R. Ussher, PhD, Jeff D. Reagan, PhD, Jason R.B. Dyck, PhD, Gary D. Lopaschuk, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 3, Pp 385-400 (2019)
Summary: Alterations in cardiac energy metabolism after a myocardial infarction contribute to the severity of heart failure (HF). Although fatty acid oxidation can be impaired in HF, it is unclear if stimulating fatty acid oxidation is a desirable ap
Externí odkaz:
https://doaj.org/article/79de453a1dda4adb8a04a801a0ccb1d3
Autor:
Kory Lavine, Junedh Amrute, Xin Luo, Vinay Penna, Andrea Bredemeyer, Tracy Yamawaki, Steven Yang, Farid Kadyrov, Gyu Heo, Sally Shi, Paul Lee, Andrew Koenig, Christoph Kuppe, Cameran Jones, Benjamin Kopecky, Sikander Hayat, Pan Ma, Yuriko Terada, Angela Fu, Milena Furtado, Daniel Kreisel, Nathan Stitziel, Chi-Ming Li, Rafael Kramann, Yongjian Liu, Brandon Ason
Inflammation and tissue fibrosis co-exist and are causally linked to organ dysfunction. However, the molecular mechanisms driving immune-fibroblast crosstalk in human cardiac disease remains unexplored and there are currently no therapeutics to targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab77004453b71869766f478a99bb1a35
https://doi.org/10.21203/rs.3.rs-2402606/v1
https://doi.org/10.21203/rs.3.rs-2402606/v1
Autor:
Junedh M. Amrute, Xin Luo, Vinay Penna, Andrea Bredemeyer, Tracy Yamawaki, Gyu Seong Heo, Sally Shi, Andrew Koenig, Steven Yang, Farid Kadyrov, Cameran Jones, Christoph Kuppe, Benjamin Kopecky, Sikander Hayat, Pan Ma, Guoshai Feng, Yuriko Terada, Angela Fu, Milena Furtado, Daniel Kreisel, Nathan O. Stitziel, Chi-Ming Li, Rafael Kramann, Yongjian Liu, Brandon Ason, Kory J. Lavine
Cardiac fibrosis is causally linked to heart failure pathogenesis and adverse clinical outcomes. However, the precise fibroblast populations that drive fibrosis in the human heart and the mechanisms that govern their emergence remain incompletely def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bbcda509fe6a0252d953dc5029290bd
https://doi.org/10.1101/2022.10.17.512579
https://doi.org/10.1101/2022.10.17.512579
Publikováno v:
Poster Presentations.
Background: The diagnosis of Giant Cell Arteritis (GCA) by Rheumatologists is based on a typical history of headache, jaw claudication and visual disturbance, examination findings such as scalp tenderness and abnormal temporal arteries, and confirmed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cf1d3ed0d3b369b310fcfc9956e7726
https://doi.org/10.1136/annrheumdis-2019-eular.5140
https://doi.org/10.1136/annrheumdis-2019-eular.5140
Autor:
Cory S. Wagg, Jeff D. Reagan, John R. Ussher, Liyan Zhang, Kenneth Milner, Dongming M. Liu, Angela Fu, Alykhan Motani, Abhishek Gupta, Osama Abo Alrob, Chaves Mary, Nikole J. Byrne, Natasha Fillmore, Pavan K. Battiprolu, Arata Fukushima, Shaohua Wang, Gary D. Lopaschuk, Khanh Nguyen, Wei Wang, Jun Mori, Tariq R. Altamimi, Jenny Ying-Lin Lu, Jason R.B. Dyck
Publikováno v:
JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 4, Iss 3, Pp 385-400 (2019)
JACC: Basic to Translational Science, Vol 4, Iss 3, Pp 385-400 (2019)
Visual Abstract
Highlights • MCD inhibition decreases fatty acid oxidation via increasing malonyl coenzyme A levels to prevent fatty acid uptake into mitochondria in the failing hearts induced by coronary artery ligation. • Downregulating fa
Highlights • MCD inhibition decreases fatty acid oxidation via increasing malonyl coenzyme A levels to prevent fatty acid uptake into mitochondria in the failing hearts induced by coronary artery ligation. • Downregulating fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::074f5ff29e2376a91baabc9d38b612d8
https://pubmed.ncbi.nlm.nih.gov/31312761
https://pubmed.ncbi.nlm.nih.gov/31312761
Autor:
Frederick A. Masoudi, Jersey Chen, Angela Fu-Chi Hsieh, Kumar Dharmarajan, Harlan M. Krumholz
Publikováno v:
Circulation. 128:2577-2584
Background— Previous studies have reported conflicting findings regarding how the incidence of heart failure (HF) after acute myocardial infarction (AMI) has changed over time, and data on contemporary national trends are sparse. Methods and Result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09cd2de85d148cf2c71cbec161141164
https://doi.org/10.1161/circulationaha.113.003668
https://doi.org/10.1161/circulationaha.113.003668
Publikováno v:
Pharmacology. 89:13-17
We report that the loop diuretic drugs bumetanide and furosemide used in the treatment of hypertension are GPR35 agonists. We utilized calcium flux, inositol phosphate accumulation, and dynamic redistribution assays to examine the pharmacology of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20f2e7c2a7e3636a55be50b803f1b745
https://doi.org/10.1159/000335127
https://doi.org/10.1159/000335127
Autor:
Aruna Mani, Ashwini Shewade, Thibaut Sanglier, Angela Fu-Chi Hsieh, Dominik Heinzmann, N. Al-Sakaff, Michael Taylor
Publikováno v:
Journal of Clinical Oncology. 36:1037-1037
1037Background: About 10–16% of mBC pts are reported to have a CNS mets diagnosis (dx; Lin JCO 2004). Data on the management of these pts are limited because they are often excluded from clinical t...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f119d3b49143010a2567a812dfe3a489
https://doi.org/10.1200/jco.2018.36.15_suppl.1037
https://doi.org/10.1200/jco.2018.36.15_suppl.1037
Publikováno v:
Journal of Clinical Oncology. 35:742-742
742 Background: The anatomical side of the colon where a tumor arises has been shown to be prognostic in patients treated with first-line therapy; patients with tumors that arise from the left side of the colon have significantly longer survival comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::961e09fa66097c7095f0908f4da3c8c0
https://doi.org/10.1200/jco.2017.35.4_suppl.742
https://doi.org/10.1200/jco.2017.35.4_suppl.742
Autor:
Jersey, Chen, Angela Fu-Chi, Hsieh, Kumar, Dharmarajan, Frederick A, Masoudi, Harlan M, Krumholz
Publikováno v:
Circulation. 128(24)
Previous studies have reported conflicting findings regarding how the incidence of heart failure (HF) after acute myocardial infarction (AMI) has changed over time, and data on contemporary national trends are sparse.Using a complete national sample
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a4581a6cd94a7c32720d1d5120284ab2
https://pubmed.ncbi.nlm.nih.gov/24190957
https://pubmed.ncbi.nlm.nih.gov/24190957