Zobrazeno 1 - 10 of 19 pro vyhledávání: '"Angela Filograna"'
1
Akademický článek
Identification and characterization of a new potent inhibitor targeting CtBP1/BARS in melanoma cells
Autor: Angela Filograna, Stefano De Tito, Matteo Lo Monte, Rosario Oliva, Francesca Bruzzese, Maria Serena Roca, Antonella Zannetti, Adelaide Greco, Daniela Spano, Inmaculada Ayala, Assunta Liberti, Luigi Petraccone, Nina Dathan, Giuliana Catara, Laura Schembri, Antonino Colanzi, Alfredo Budillon, Andrea Rosario Beccari, Pompea Del Vecchio, Alberto Luini, Daniela Corda, Carmen Valente
Publikováno v: Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-32 (2024)
Abstract Background The C-terminal-binding protein 1/brefeldin A ADP-ribosylation substrate (CtBP1/BARS) acts both as an oncogenic transcriptional co-repressor and as a fission inducing protein required for membrane trafficking and Golgi complex part
Externí odkaz: https://doaj.org/article/1518a1c715734851bf4b6f4560bdaa4e
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2
Akademický článek
Protein Amphipathic Helix Insertion: A Mechanism to Induce Membrane Fission
Autor: Mikhail A. Zhukovsky, Angela Filograna, Alberto Luini, Daniela Corda, Carmen Valente
Publikováno v: Frontiers in Cell and Developmental Biology, Vol 7 (2019)
One of the fundamental features of biomembranes is the ability to fuse or to separate. These processes called respectively membrane fusion and fission are central in the homeostasis of events such as those related to intracellular membrane traffic. P
Externí odkaz: https://doaj.org/article/187e9c124a05438dbd29aa1d0df50a9f
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3
Akademický článek
The Structure and Function of Acylglycerophosphate Acyltransferase 4/ Lysophosphatidic Acid Acyltransferase Delta (AGPAT4/LPAATδ)
Autor: Mikhail A. Zhukovsky, Angela Filograna, Alberto Luini, Daniela Corda, Carmen Valente
Publikováno v: Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Lipid-modifying enzymes serve crucial roles in cellular processes such as signal transduction (producing lipid-derived second messengers), intracellular membrane transport (facilitating membrane remodeling needed for membrane fusion/fission), and pro
Externí odkaz: https://doaj.org/article/51a93cd40da049798500ce15971e273a
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4
Akademický článek
Three-dimensional label-free imaging throughout adipocyte differentiation by stimulated Raman microscopy.
Autor: Maria Antonietta Ferrara, Angela Filograna, Rajeev Ranjan, Daniela Corda, Carmen Valente, Luigi Sirleto
Publikováno v: PLoS ONE, Vol 14, Iss 5, p e0216811 (2019)
Lipid droplets are lipid-storage organelles with a key role in lipid accumulation pathologies such as diabetes, obesity and atherosclerosis. Despite their important functions many aspects of lipid droplets biology are still unknown. This is partially
Externí odkaz: https://doaj.org/article/1f1c80a9e11d42b7ada4915211f769c3
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5
Akademický článek
Golgi membrane fission requires the CtBP1-S/BARS-induced activation of lysophosphatidic acid acyltransferase δ
Autor: Alessandro Pagliuso, Carmen Valente, Lucia Laura Giordano, Angela Filograna, Guiling Li, Diego Circolo, Gabriele Turacchio, Vincenzo Manuel Marzullo, Luigi Mandrich, Mikhail A. Zhukovsky, Fabio Formiggini, Roman S. Polishchuk, Daniela Corda, Alberto Luini
Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
CtBP1-S/BARS is required for fission of endomembrane compartments including the Golgi. Here the authors show that CtBP1-S/BARS activates a trans-Golgi lysophosphatidic acid acyltransferase that catalyses the production of phosphatidic acid and is req
Externí odkaz: https://doaj.org/article/1bf20b6b1a8247ee8ba8f6c692dbce44
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7
PKD-dependent PARP12-catalyzed mono-ADP-ribosylation of Golgin-97 is required for E-cadherin transport from Golgi to plasma membrane
Autor: Giovanna Grimaldi, Angela Filograna, Laura Schembri, Matteo Lo Monte, Rosaria Di Martino, Marinella Pirozzi, Daniela Spano, Andrea R. Beccari, Seetharaman Parashuraman, Alberto Luini, Carmen Valente, Daniela Corda
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Significance Proteins are modified by many posttranslational modifications (PTMs) with crucial regulatory functions. A PTM attracting increasing interest is ADP-ribosylation, capable of altering crucial cellular targets. We show that mono-ADP-ribosyl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2093b871ecc54494d3273fb3e42264b3
https://doi.org/10.1073/pnas.2026494119
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8
Phosphatidic acid in membrane rearrangements
Autor: Daniela Corda, Alberto Luini, Angela Filograna, Mikhail A. Zhukovsky, Carmen Valente
Publikováno v: FEBS letters
593 (2019): 2428–2451. doi:10.1002/1873-3468.13563
info:cnr-pdr/source/autori:Zhukovsky, Mikhail A.; Filograna, Angela; Luini, Alberto; Corda, Daniela; Valente, Carmen/titolo:Phosphatidic acid in membrane rearrangements/doi:10.1002%2F1873-3468.13563/rivista:FEBS letters (Print)/anno:2019/pagina_da:2428/pagina_a:2451/intervallo_pagine:2428–2451/volume:593
Phosphatidic acid (PA) is the simplest cellular glycerophospholipid characterized by unique biophysical properties: a small headgroup; negative charge; and a phosphomonoester group. Upon interaction with lysine or arginine, PA charge increases from -
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3100f6dba976cf40f1a3cef974d867fa
https://doi.org/10.1002/1873-3468.13563
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9
Protein Amphipathic Helix Insertion: A Mechanism to Induce Membrane Fission
Autor: Carmen Valente, Daniela Corda, Angela Filograna, Alberto Luini, Mikhail A. Zhukovsky
Publikováno v: Frontiers in Cell and Developmental Biology 7 (2019). doi:10.3389/fcell.2019.00291
info:cnr-pdr/source/autori:Zhukovsky, Mikhail A.; Filograna, Angela; Luini, Alberto; Corda, Daniela; Valente, Carmen/titolo:Protein Amphipathic Helix Insertion: A Mechanism to Induce Membrane Fission/doi:10.3389%2Ffcell.2019.00291/rivista:Frontiers in Cell and Developmental Biology/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:7
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
One of the fundamental features of biomembranes is the ability to fuse or to separate. These processes called respectively membrane fusion and fission are central in the homeostasis of events such as those related to intracellular membrane traffic. P
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020778bffa155e4b3cafe012b151021c
https://doi.org/10.3389/fcell.2019.00291
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10
The Structure and Function of Acylglycerophosphate Acyltransferase 4/ Lysophosphatidic Acid Acyltransferase Delta (AGPAT4/LPAATδ)
Autor: Carmen Valente, Alberto Luini, Mikhail A. Zhukovsky, Angela Filograna, Daniela Corda
Publikováno v: Frontiers in Cell and Developmental Biology 7 (2019). doi:10.3389/fcell.2019.00147
info:cnr-pdr/source/autori:Zhukovsky M.A.; Filograna A.; Luini A.; Corda D.; Valente C./titolo:The structure and function of acylglycerophosphate acyltransferase 4%2Flysophosphatidic acid acyltransferase delta (AGPAT4%2FLPAAT?)/doi:10.3389%2Ffcell.2019.00147/rivista:Frontiers in Cell and Developmental Biology/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:7
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Frontiers in Cell and Developmental Biology
Lipid-modifying enzymes serve crucial roles in cellular processes such as signal transduction (producing lipid-derived second messengers), intracellular membrane transport (facilitating membrane remodeling needed for membrane fusion/fission), and pro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::959f5d4a6c3c269e33f532cfd8d757b7
https://doi.org/10.3389/fcell.2019.00147
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