Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Angela Everhart"'
Publikováno v:
ASN Neuro, Vol 13 (2021)
Metabolic adaptations in the brain are critical to the establishment and maintenance of normal cellular functions and to the pathological responses to disease processes. Here, we have focused on specific metabolic pathways that are involved in immune
Externí odkaz:
https://doaj.org/article/28b6f04885ce4b78a02b9fd83096d6c7
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31993 (2012)
Lithium is an anti-psychotic that has been shown to prevent the hyperphosphorylation of tau protein through the inhibition of glycogen-synthase kinase 3-beta (GSK3β). We recently developed a mouse model that progresses from amyloid pathology to tau
Externí odkaz:
https://doaj.org/article/338f4947c8dc4c3689e37d39e522c5bc
Autor:
Donna M Wilcock, Qun Zhao, Dave Morgan, Marcia N Gordon, Angela Everhart, Joan G Wilson, Jennifer E Lee, Carol A Colton
Publikováno v:
ASN Neuro, Vol 3 (2011)
While the presence of an inflammatory response in AD (Alzheimer's disease) is well known, the data on inflammation are conflicting, suggesting that inflammation either attenuates pathology, exacerbates it or has no effect. Our goal was to more fully
Externí odkaz:
https://doaj.org/article/254f598d7ff34b4db8c9c848010526b3
Publikováno v:
ASN NEURO
ASN Neuro, Vol 13 (2021)
ASN Neuro, Vol 13 (2021)
Metabolic adaptations in the brain are critical to the establishment and maintenance of normal cellular functions and to the pathological responses to disease processes. Here, we have focused on specific metabolic pathways that are involved in immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::666cffab2c00b0dd3a93b5f25eee7578
http://europepmc.org/articles/PMC8207264
http://europepmc.org/articles/PMC8207264
Publikováno v:
Alzheimer's & Dementia. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70ba71c8e8dae444fba25fdcbb64d5b1
https://doi.org/10.1016/j.jalz.2018.06.855
https://doi.org/10.1016/j.jalz.2018.06.855
Autor:
Marilyn Jansen, Andrew N. Hoofnagle, Candice M. Brown, Jennifer E. Lee, Joan G. Wilson, Michael D. Gunn, Carol A. Colton, Matthew J. Kan, Michael P. Vitek, Angela Everhart
Publikováno v:
The Journal of Neuroscience. 35:5969-5982
The pathogenesis of Alzheimer's disease (AD) is a critical unsolved question; and although recent studies have demonstrated a strong association between altered brain immune responses and disease progression, the mechanistic cause of neuronal dysfunc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::051e2490cff33f4009ed00f8d843b4cc
https://doi.org/10.1523/jneurosci.4668-14.2015
https://doi.org/10.1523/jneurosci.4668-14.2015
Autor:
Jukka Puoliväli, Angela Everhart, Juho Oksman, Teemu Laitinen, Kimmo Lehtimäki, Nina Vartiainen, Joan G. Wilson, Carol A. Colton, Michael P. Vitek, Olli Jääskeläinen, Donna M. Wilcock, Taneli Heikkinen
Publikováno v:
Journal of Neuropathology and Experimental Neurology
Supplemental digital content is available in the text.
Understanding the pathophysiologic mechanisms underlying Alzheimer disease relies on knowledge of disease onset and the sequence of development of brain pathologies. We present a comprehensi
Understanding the pathophysiologic mechanisms underlying Alzheimer disease relies on knowledge of disease onset and the sequence of development of brain pathologies. We present a comprehensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::959c4cb585e46a99316ac45f2f9fd488
http://europepmc.org/articles/PMC4131941
http://europepmc.org/articles/PMC4131941
Autor:
Michael P. Vitek, Lisa A. Ridnour, Marilyn Jansen, Angela Everhart, David A. Wink, Michael D. Hoos, Joan G. Wilson, Carol A. Colton
Publikováno v:
Molecular Neurodegeneration
Background Mouse models are used in the study of human disease. Despite well-known homologies, the difference in immune response between mice and humans impacts the application of data derived from mice to human disease outcomes. Nitric oxide synthas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e4ab6d6422117c635de25a0b8e4119
https://doi.org/10.1186/1750-1326-9-50
https://doi.org/10.1186/1750-1326-9-50
Autor:
Matthew W. Foster, Brenna M. Richardson, Carol A. Colton, J. Will Thompson, M. Arthur Moseley, Michael D. Hoos, Angela Everhart
Publikováno v:
Journal of proteome research. 12(10)
Alzheimer's disease (AD) is a complex neurodegenerative process that involves altered brain immune, neuronal and metabolic functions. Understanding the underlying mechanisms has relied on mouse models that mimic components of AD pathology. We used ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aafeaef63cda69e0e42d3cabdf91ee0a
https://pubmed.ncbi.nlm.nih.gov/24006891
https://pubmed.ncbi.nlm.nih.gov/24006891