Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Angela Egert"'
Autor:
Julia Armbruster, Mostafa A. Aboouf, Max Gassmann, Angela Egert, Hubert Schorle, Veit Hornung, Tobias Schmidt, Jonathan L. Schmid-Burgk, Glen Kristiansen, Anne Bicker, Thomas Hankeln, Hao Zhu, Thomas A. Gorr
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
Myoglobin (MB) is known to bind and deliver oxygen in striated muscles at high expression levels. MB is also expressed at much reduced levels in mammary epithelial cells, where the protein´s function is unclear. In this study, we aim to determine wh
Externí odkaz:
https://doaj.org/article/034667929e304d02929e2820f85604a6
Autor:
Daniel Holl, Peter Kuckenberg, Tatiana Woynecki, Angela Egert, Astrid Becker, Sebastian Huss, Dirk Stabenow, Andreas Zimmer, Percy Knolle, René Tolba, Hans-Peter Fischer, Hubert Schorle
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22034 (2011)
BackgroundThe transcription factor Tcfap2c has been demonstrated to be essential for various processes during mammalian development. It has been found to be upregulated in various undifferentiated tumors and is implicated with poor prognosis. Tcfap2c
Externí odkaz:
https://doaj.org/article/173b8efce5f548cc942fd9a96206ad71
Autor:
Hubert Schorle, Klaus Willecke, Philipp Wörsdörfer, Angela Egert, Frank Edenhofer, Thileepan Sekaran, Felicitas Bosen, Alexander Pfeifer, Süleyman Ergün, Martina Gebhardt, David Komla Kessie, Katrin Zimmermann, Nicole Russ
Publikováno v:
Stem Cells. 35:859-871
Gap junctional intercellular communication (GJIC) has been suggested to be involved in early embryonic development but the actual functional role remained elusive. Connexin (Cx) 43 and Cx45 are co-expressed in embryonic stem (ES) cells, form gap junc
Autor:
Roland Schüle, Magdalena Rohde, Andreas Janzer, Jutta Kirfel, Dominica Willmann, Hubert Schorle, Angela Egert, Elisabeth Sievers
Publikováno v:
Experimental Cell Research. 348:123-131
Cell migration is a central process in the development and maintenance of multicellular organisms. Tissue formation during embryonic development, wound healing, immune responses and invasive tumors all require the orchestrated movement of cells to sp
Publikováno v:
Molecular and Cellular Biology. 29:881-891
The development and growth of the skull is controlled by cranial sutures, which serve as growth centers for osteogenesis by providing a pool of osteoprogenitors. These osteoprogenitors undergo intramembranous ossification by direct differentiation in
Autor:
Kathrin Klee, Thomas Ulas, Oliver Brüstle, Patrick Günther, Joachim L. Schultze, Marc Beyer, Hubert Schorle, Waldemar Kolanus, Angela Egert, Kevin Bassler, Karin Schneider, Sibylle Mitschka, Tobias Goller, Jia Xue, Jerome Mertens
Publikováno v:
Scientific Reports
Regulatory networks for differentiation and pluripotency in embryonic stem (ES) cells have long been suggested to be mutually exclusive. However, with the identification of many new components of these networks ranging from epigenetic, transcriptiona
Autor:
Joseph Neulen, Walter Stöcker, André Hildebrand, Eileen Dietzel, Yuliya Gottenbusch, Silke Ensslen, Thomas Veitinger, Angela Egert, Cora Schäfer, Benjamin Rösing, Ralf Weiskirchen, Jennifer Wessling, Thomas Renné, Tanja Tropartz, Irene Yiallouros, Julia Floehr, Willi Jahnen-Dechent, Marc Spehr, Hubert Schorle, Rene Tolba, Bernd Denecke
Publikováno v:
Developmental cell. 25(1)
SummaryThe zona pellucida (ZP) is a glycoprotein matrix surrounding mammalian oocytes. Upon fertilization, ZP hardening prevents sperm from binding to and penetrating the ZP. Here, we report that targeted gene deletion of the liver-derived plasma pro
Autor:
Hubert Schorle, Percy A. Knolle, Sebastian Huss, Angela Egert, Peter Kuckenberg, D Stabenow, Astrid Becker, Hans-Peter Fischer, Daniel Holl, Tatiana Woynecki, Andreas Zimmer, Rene Tolba
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 7, p e22034 (2011)
PLOS ONE 6(7), e22034 (2011). doi:10.1371/journal.pone.0022034
PLoS ONE, Vol 6, Iss 7, p e22034 (2011)
PLOS ONE 6(7), e22034 (2011). doi:10.1371/journal.pone.0022034
PLoS one 6(7), e22034 (2011). doi:10.1371/journal.pone.0022034
Published by PLoS [u.a.], Lawrence, Kan.
Published by PLoS [u.a.], Lawrence, Kan.
Autor:
Oliver Brüstle, Caroline Kubaczka, Michael Peitz, Astrid Becker, Angela Egert, Andreas Zimmer, Eva Wardelmann, Hubert Schorle, Peter Kuckenberg
Publikováno v:
Molecular and cellular biology. 31(8)
In mammals, the first cell fate decision is initialized by cell polarization at the 8- to 16-cell stage of the preimplantation embryo. At this stage, outside cells adopt a trophectoderm (TE) fate, whereas the inside cell population gives rise to the
Autor:
Christoph Patsch, Hubert Schorle, Frank Edenhofer, Angela Egert, Richard Jäger, Michael Peitz, Andrea Jäger
Publikováno v:
Genesis (New York, N.Y. : 2000). 45(8)
Continuous expression of Cre recombinase has the potential to yield toxic side effects in various cell types, thereby limiting applications of the Cre/loxP system for conditional mutagenesis. In this study, we investigate the potential of Cre protein