Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Angela D Wright"'
Autor:
Ashleigh Trimble, Victoria Connor, Ryan E Robinson, Daniella McLenaghan, Carole A Hancock, Duolao Wang, Stephen B Gordon, Daniela M Ferreira, Angela D Wright, Andrea M Collins
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229558 (2020)
IntroductionPneumococcal colonisation is regarded as a pre-requisite for developing pneumococcal disease. In children previous studies have reported pneumococcal colonisation to be a symptomatic event and described a relationship between symptom seve
Externí odkaz:
https://doaj.org/article/308401acedc7437c8361f384baf0f49b
Autor:
Seher Raza Zaidi, Andrea M. Collins, Elena Mitsi, Jesús Reiné, Kayleigh Davies, Angela D Wright, Jessica Owugha, Richard Fitzgerald, Amitava Ganguli, Stephen B Gordon, Daniela Mulari Ferreira, Jamie Rylance
Publikováno v:
BMC Pulmonary Medicine, Vol 17, Iss 1, Pp 1-5 (2017)
Abstract Background Broncho alveolar lavage (BAL) is widely used for investigative research to study innate, cellular and humoral immune responses, and in early phase drug trials. Conventional (multiple use) flexible bronchoscopes have time and monet
Externí odkaz:
https://doaj.org/article/0ab3909d24a6432eb990cea59c1f4330
Autor:
Simon P Jochems, Katherine Piddock, Jamie Rylance, Hugh Adler, Beatriz F Carniel, Andrea Collins, Jenna F Gritzfeld, Carole Hancock, Helen Hill, Jesus Reiné, Alexandra Seddon, Carla Solórzano, Syba Sunny, Ashleigh Trimble, Angela D Wright, Seher Zaidi, Stephen B Gordon, Daniela M Ferreira
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169805 (2017)
The morbidity and mortality related to respiratory tract diseases is enormous, with hundreds of millions of individuals afflicted and four million people dying each year. Understanding the immunological processes in the mucosa that govern outcome fol
Externí odkaz:
https://doaj.org/article/9fc1a4b9902f4cd0b85040843a1bbcfa
Autor:
Adam K A Wright, Mathieu Bangert, Jenna F Gritzfeld, Daniela M Ferreira, Kondwani C Jambo, Angela D Wright, Andrea M Collins, Stephen B Gordon
Publikováno v:
PLoS Pathogens, Vol 9, Iss 3, p e1003274 (2013)
Pneumococcal carriage is both immunising and a pre-requisite for mucosal and systemic disease. Murine models of pneumococcal colonisation show that IL-17A-secreting CD4(+) T-cells (Th-17 cells) are essential for clearance of pneumococci from the naso
Externí odkaz:
https://doaj.org/article/991ee9a5e40343629520074aa869eb22
Autor:
Adam K A Wright, Daniela M Ferreira, Jenna F Gritzfeld, Angela D Wright, Kathryn Armitage, Kondwani C Jambo, Emily Bate, Sherouk El Batrawy, Andrea Collins, Stephen B Gordon
Publikováno v:
PLoS Pathogens, Vol 8, Iss 4, p e1002622 (2012)
Infectious challenge of the human nasal mucosa elicits immune responses that determine the fate of the host-bacterial interaction; leading either to clearance, colonisation and/or disease. Persistent antigenic exposure from pneumococcal colonisation
Externí odkaz:
https://doaj.org/article/66e905982c694e28a711f28005765625
Autor:
Carole A. Hancock, Daniela M. Ferreira, Stephen B. Gordon, Daniella McLenaghan, Angela D. Wright, Victoria Connor, Duolao Wang, Ryan E. Robinson, Ashleigh Trimble, Andrea M. Collins
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229558 (2020)
PLoS ONE
PLoS ONE
Introduction\ud Pneumococcal colonisation is regarded as a pre-requisite for developing pneumococcal disease. In children previous studies have reported pneumococcal colonisation to be a symptomatic event and described a relationship between symptom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aabaf3697c6d39952da4f7fcefaa536
https://archive.lstmed.ac.uk/13790/6/10.1371_journal.pone.0229558.pdf
https://archive.lstmed.ac.uk/13790/6/10.1371_journal.pone.0229558.pdf
Autor:
Andrea M. Collins, Ryan E. Robinson, Angela D. Wright, Ashleigh Trimble, Duolao Wang, Stephen B. Gordon, Victoria Connor, Daniela M. Ferreira, Carole A. Hancock
IntroductionPneumococcal colonisation is regarded as a pre-requisite for developing pneumococcal disease. In children previous studies have reported colonisation to be a symptomatic event and described a relationship between symptom severity/frequenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30894068525b40b6ee8b3068abfff5f8
https://doi.org/10.1101/652370
https://doi.org/10.1101/652370
Autor:
Gowrisankar Rajam, Ben Morton, Jesús Reiné, Edwin W. Ades, Robert Parker, Angela D. Wright, Elena Mitsi, Duolao Wang, John D Blakey, Ingeborg Welters, Stephen B. Gordon, Shaun H. Pennington, Daniela M. Ferreira, Aras Kadioglu
Publikováno v:
SHOCK
INTRODUCTION\ud Antimicrobial resistance threatens to undermine treatment for severe infection; new therapeutic strategies are urgently needed. Pre-clinical work shows that augmented passive immunotherapy with P4 peptide increases phagocytic activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e575408b652d8db547cbab3f12961568
https://doi.org/10.1097/shk.0000000000000715
https://doi.org/10.1097/shk.0000000000000715
Autor:
M. Garner-Jones, Duolao Wang, Angela D. Wright, Shaun H. Pennington, Stephen B. Gordon, Daniela M. Ferreira, Eliane N. Miyaji, Cintia F. M. Vadesilho, M J Hopkins, Jenna F. Gritzfeld, N. Coombes, Andrea M. Collins, Sarah J. Glennie
Publikováno v:
Mucosal Immunology
Increased nasopharyngeal colonization density has been associated with pneumonia. We used experimental human pneumococcal carriage to investigate whether upper respiratory tract viral infection predisposes individuals to carriage. A total of 101 heal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee76862e7001e6f323b1cb70c5e3a42
https://doi.org/10.1038/mi.2015.35
https://doi.org/10.1038/mi.2015.35
Autor:
Carole A. Hancock, Duolao Wang, Jenna F. Gritzfeld, Andrea M. Collins, Angela D. Wright, Shaun H. Pennington, Daniela M. Ferreira, Elena Mitsi, Ben Morton, Stephen B. Gordon
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 192:853-858
New vaccines are urgently needed to protect the vulnerable from bacterial pneumonia. Clinical trials of pneumonia vaccines are slow and costly, requiring tens of thousands of patients. Studies of pneumococcal vaccine efficacy against colonization hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb2b8dcafb6a6b9a0253e51cb218aac4
https://doi.org/10.1164/rccm.201503-0542oc
https://doi.org/10.1164/rccm.201503-0542oc