Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Angela D Williams"'
Autor:
Monichan Phay, Alfred T Welzel, Angela D Williams, Helen P McWilliams-Koeppen, Veronika Blinder, Tiernan T O'Malley, Alan Solomon, Dominic M Walsh, Brian O'Nuallain
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137344 (2015)
Amyloid-reactive IgGs isolated from pooled blood of normal individuals (pAbs) have demonstrated clinical utility for amyloid diseases by in vivo targeting and clearing amyloidogenic proteins and peptides. We now report the following three novel findi
Externí odkaz:
https://doaj.org/article/d9c973e149054991ba50bef3823c4302
Autor:
Alfred T Welzel, Angela D Williams, Helen P McWilliams-Koeppen, Luis Acero, Alfred Weber, Veronika Blinder, Alex Mably, Sebastian Bunk, Corinna Hermann, Michael A Farrell, Hartmut J Ehrlich, Hans P Schwarz, Dominic M Walsh, Alan Solomon, Brian O'Nuallain
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50317 (2012)
Soluble non-fibrillar assemblies of amyloid-beta (Aβ) and aggregated tau protein are the proximate synaptotoxic species associated with Alzheimer's disease (AD). Anti-Aβ immunotherapy is a promising and advanced therapeutic strategy, but the precis
Externí odkaz:
https://doaj.org/article/b5e5d024a32647f4acc8c5e30db8eff6
Autor:
James S. Foster, Manasi Balachandran, Trevor J. Hancock, Emily B. Martin, Sallie Macy, Craig Wooliver, Tina Richey, Alan Stuckey, Angela D. Williams, Joseph W. Jackson, Stephen J. Kennel, Jonathan S. Wall
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSystemic amyloidosis is a progressive disorder characterized by the extracellular deposition of amyloid fibrils and accessory proteins in visceral organs and tissues. Amyloid accumulation causes organ dysfunction and is not generally clea
Externí odkaz:
https://doaj.org/article/3ce636148a204e3aafd0f0efaec0fd54
Autor:
Joseph W. Jackson, James S. Foster, Emily B. Martin, Sallie Macy, Craig Wooliver, Manasi Balachandran, Tina Richey, R. Eric Heidel, Angela D. Williams, Stephen J. Kennel, Jonathan S. Wall
Publikováno v:
Amyloid. :1-12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd06c6460612ca06556a2071d6bbb6f9
https://doi.org/10.1080/13506129.2022.2155133
https://doi.org/10.1080/13506129.2022.2155133
Autor:
Jonathan S, Wall, Emily B, Martin, Aaron, Endsley, Alan C, Stuckey, Angela D, Williams, Dustin, Powell, Bryan, Whittle, Sarah, Hall, Tyler R, Lambeth, Ryan R, Julian, Michael, Stabin, Ronald H, Lands, Stephen J, Kennel
Publikováno v:
Molecular imaging and biology. 24(3)
Accurate diagnosis of amyloidosis remains a significant clinical challenge and unmet need for patients. The amyloid-reactive peptide p5+14 radiolabeled with iodine-124 has been developed for the detection of amyloid by PET/CT imaging. In a first-in-h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9a081654bcfb59baca79913553c509b5
https://pubmed.ncbi.nlm.nih.gov/34786667
https://pubmed.ncbi.nlm.nih.gov/34786667
Autor:
Joseph W, Jackson, Trevor J, Hancock, Pranay, Dogra, Ravi, Patel, Ravit, Arav-Boger, Angela D, Williams, Stephen J, Kennel, Jonathan S, Wall, Tim E, Sparer
Publikováno v:
mSphere
In the absence of an effective vaccine to prevent HCMV infections, alternative interventions must be developed. Prevention of viral entry into susceptible cells is an attractive alternative strategy. Here we report that heparan sulfate-binding peptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a1d5c71b06f95ce9814ea8d46b058e1d
https://pubmed.ncbi.nlm.nih.gov/30760613
https://pubmed.ncbi.nlm.nih.gov/30760613
Autor:
James S. Foster, Angela D. Williams, Sallie Macy, Tina Richey, Alan Stuckey, Daniel Craig Wooliver, Richa Koul-Tiwari, Emily B. Martin, Stephen J. Kennel, Jonathan S. Wall
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Frontiers in Immunology
Frontiers in Immunology
There is a continuing need for therapeutic interventions for patients with the protein misfolding disorders that result in systemic amyloidosis. Recently, specific antibodies have been employed to treat AL amyloidosis by opsonizing tissue amyloid dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::906d06e016f5dde98e04505a2ec70ab2
https://doi.org/10.3389/fimmu.2017.01082
https://doi.org/10.3389/fimmu.2017.01082
Publikováno v:
Antiviral research. 71(1)
Orthopoxviruses and herpesviruses are both large enveloped DNA viruses, yet these virus families exhibit very different susceptibilities to antiviral drugs. We investigated the activation of nucleoside analogs by the types I and II thymidine kinase (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69d4e44e0596ddc0b258d1118c3a6c49
https://pubmed.ncbi.nlm.nih.gov/16530858
https://pubmed.ncbi.nlm.nih.gov/16530858