Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Angela Choi"'
Autor:
Diana Cadena Castaneda, Sonia Jangra, Marina Yurieva, Jan Martinek, Megan Callender, Matthew Coxe, Angela Choi, Juan García-Bernalt Diego, Te-Chia Wu, Florentina Marches, Damien Chaussabel, Adolfo García-Sastre, Michael Schotsaert, Adam Williams, Karolina Palucka
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102735- (2023)
Summary: Primary human lung organoid-derived air-liquid interface (ALI) cultures serve as a physiologically relevant model to study human airway epithelium in vitro. Here, we present a protocol for establishing these cultures from cryopreserved human
Externí odkaz:
https://doaj.org/article/b465519e6c2441c6bdb976ce7b5806cd
Autor:
Lauren A. Chang, Angela Choi, Raveen Rathnasinghe, Prajakta Warang, Moataz Noureddine, Sonia Jangra, Yong Chen, Bruno G. De Geest, Michael Schotsaert
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Eosinophils are important mediators of mucosal tissue homeostasis, anti-helminth responses, and allergy. Lung eosinophilia has previously been linked to aberrant Type 2-skewed T cell responses to respiratory viral infection and may also be a conseque
Externí odkaz:
https://doaj.org/article/f7543b749d5d433c9261b41937fc7018
Autor:
Diana Cadena Castaneda, Sonia Jangra, Marina Yurieva, Jan Martinek, Megan Callender, Matthew Coxe, Angela Choi, Juan García-Bernalt Diego, Jianan Lin, Te-Chia Wu, Florentina Marches, Damien Chaussabel, Peter Yu, Andrew Salner, Gabrielle Aucello, Jonathan Koff, Briana Hudson, Sarah E. Church, Kara Gorman, Esperanza Anguiano, Adolfo García-Sastre, Adam Williams, Michael Schotsaert, Karolina Palucka
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107374- (2023)
Summary: The COVID-19 pandemic continues to be a health crisis with major unmet medical needs. The early responses from airway epithelial cells, the first target of the virus regulating the progression toward severe disease, are not fully understood.
Externí odkaz:
https://doaj.org/article/b51b64e50b72469895f79ce437b3fedc
Autor:
Raveen Rathnasinghe, Sonia Jangra, Chengjin Ye, Anastasija Cupic, Gagandeep Singh, Carles Martínez-Romero, Lubbertus C. F. Mulder, Thomas Kehrer, Soner Yildiz, Angela Choi, Stephen T. Yeung, Ignacio Mena, Virginia Gillespie, Jana De Vrieze, Sadaf Aslam, Daniel Stadlbauer, David A. Meekins, Chester D. McDowell, Velmurugan Balaraman, Michael J. Corley, Juergen A. Richt, Bruno G. De Geest, Lisa Miorin, PVI study group, Florian Krammer, Luis Martinez-Sobrido, Viviana Simon, Adolfo García-Sastre, Michael Schotsaert
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Here, Rathnasinghe et al. characterize the pathogenesis of a mouse-adapted SARS-CoV-2 in infected obese and aged mice, and identify mutations that are present in SARS-CoV-2 variants of concern, associated with higher transmissibility.
Externí odkaz:
https://doaj.org/article/12c6e893f2b043239df7246c95215cf6
Autor:
Sonia Jangra, Gabriel Laghlali, Angela Choi, Raveen Rathnasinghe, Yong Chen, Soner Yildiz, Lynda Coughlan, Adolfo García-Sastre, Bruno G. De Geest, Michael Schotsaert
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Influenza vaccine effectiveness could be improved by combination with an adjuvant with the potential to enhance the host-vaccine response both quantitatively and qualitatively. The goal of this study was to explore a RIG-I agonist (SDI-nanogel) and a
Externí odkaz:
https://doaj.org/article/8948680f21d34497a5a69b874b6560f4
Autor:
Angela Choi, Lorena I. Ibañez, Shirin Strohmeier, Florian Krammer, Adolfo García-Sastre, Michael Schotsaert
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Conventional influenza vaccines aim at the induction of virus-neutralizing antibodies that provide with sterilizing immunity. However, influenza vaccination often confers protection from disease but not from infection. The impact of infection-permiss
Externí odkaz:
https://doaj.org/article/24cd9e2bb6d944a3af607ff52e1c6315
Autor:
Mohammad Amin Behzadi, James Duehr, Angela Choi, Michael Schotsaert, Adolfo García-Sastre, Peter Palese, Raffael Nachbagauer
Publikováno v:
Proceedings, Vol 50, Iss 1, p 132 (2020)
Human rhinoviruses (RVs) are the main cause of the common cold worldwide. To date, more than 160 serotypes of the virus have been recognized. These viruses are categorized into three major groups: A, B, and C. There are currently no approved vaccines
Externí odkaz:
https://doaj.org/article/a92569adb00c4e1c9268bf501cfa6065
Autor:
Henning Jacobsen, Madhusudan Rajendran, Angela Choi, Haakon Sjursen, Karl A. Brokstad, Rebecca J. Cox, Peter Palese, Florian Krammer, Raffael Nachbagauer
Publikováno v:
mBio, Vol 8, Iss 5 (2017)
ABSTRACT The immunogenicity of current influenza virus vaccines is assessed by measuring an increase of influenza virus-specific antibodies in a hemagglutination inhibition assay. This method exclusively measures antibodies against the hemagglutinin
Externí odkaz:
https://doaj.org/article/d709eec0ace54c98a0b1c220de07b37d
Publikováno v:
Vaccines, Vol 7, Iss 3, p 113 (2019)
Background: Influenza virus infection predisposes to secondary bacterial pneumonia. Currently licensed influenza vaccines aim at the induction of neutralizing antibodies and are less effective if the induction of neutralizing antibodies is low and/or
Externí odkaz:
https://doaj.org/article/1303de7f93ca48969c1367b2fd70f510
Publikováno v:
mBio, Vol 7, Iss 1 (2016)
ABSTRACT Influenza remains a major global health burden. Seasonal vaccines offer protection but can be rendered less effective when the virus undergoes extensive antigenic drift. Antibodies that target the highly conserved hemagglutinin stalk can pro
Externí odkaz:
https://doaj.org/article/099e8f0ae81d4590b94040db24f17f57