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pro vyhledávání: '"Angela Casadio"'
Autor:
Sophie Hempel, Nicholas A. Morrice, Angela Casadio, Mary A O'Connell, Simona Paro, Liam Keegan, James Brindle, Giannino Del Sal, Roberto Marcucci, Andrea Bisso
Publikováno v:
The EMBO Journal. 30:4211-4222
ADAR2 catalyses the deamination of adenosine to inosine at the GluR2 Q/R site in the pre-mRNA encoding the critical subunit of AMPA receptors. Among ADAR2 substrates this is the vital one as editing at this position is indispensable for normal brain