Zobrazeno 1 - 10
of 311
pro vyhledávání: '"Angela C. Shore"'
Autor:
Andrew N. Jordan, Christine Anning, Lindsay Wilkes, Claire Ball, Nicola Pamphilon, Christopher E. Clark, Nicholas G. Bellenger, Angela C. Shore, Andrew S. P. Sharp, Jose M. Valderas
Publikováno v:
Health and Quality of Life Outcomes, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract Background Hypertension is a highly prevalent condition, with optimal treatment to BP targets conferring significant gains in terms of cardiovascular outcomes. Understanding why some patients do not achieve BP targets would be enhanced throu
Externí odkaz:
https://doaj.org/article/1a66dbfedbc04164b112da27c56ed56f
Autor:
Chuanyan Wu, Yan Borné, Rui Gao, Maykel López Rodriguez, William C. Roell, Jonathan M. Wilson, Ajit Regmi, Cheng Luan, Dina Mansour Aly, Andreas Peter, Jürgen Machann, Harald Staiger, Andreas Fritsche, Andreas L. Birkenfeld, Rongya Tao, Robert Wagner, Mickaël Canouil, Mun-Gwan Hong, Jochen M. Schwenk, Emma Ahlqvist, Minna U. Kaikkonen, Peter Nilsson, Angela C. Shore, Faisel Khan, Andrea Natali, Olle Melander, Marju Orho-Melander, Jan Nilsson, Hans-Ulrich Häring, Erik Renström, Claes B. Wollheim, Gunnar Engström, Jianping Weng, Ewan R. Pearson, Paul W. Franks, Morris F. White, Kevin L. Duffin, Allan Arthur Vaag, Markku Laakso, Norbert Stefan, Leif Groop, Yang De Marinis
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Follistatin promotes in type 2 diabetes (T2D) pathogenesis in model animals and is elevated in patients with T2D. Here the authors report that plasma follistatin associates with increased risk of incident T2D in two longitudinal cohorts, and show tha
Externí odkaz:
https://doaj.org/article/718976e80f5648f99659b5ea904f47e5
Autor:
Andrew N. Jordan, Jon Fulford, Kim Gooding, Christine Anning, Lindsay Wilkes, Claire Ball, Nicola Pamphilon, David Mawson, Christopher E. Clark, Angela C. Shore, Andrew S. P. Sharp, Nicholas G. Bellenger
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 23, Iss 1, Pp 1-11 (2021)
Abstract Background Left ventricular (LV) hypertrophy (LVH) in uncontrolled hypertension is an independent predictor of mortality, though its regression with treatment improves outcomes. Retrospective data suggest that early control of hypertension p
Externí odkaz:
https://doaj.org/article/688c5272a3004040832af28a006555d8
Autor:
Annelie Shami, Andreas Edsfeldt, Eva Bengtsson, Jan Nilsson, Angela C. Shore, Andrea Natali, Faisel Khan, Esther Lutgens, Isabel Gonçalves
Publikováno v:
Journal of Stroke, Vol 23, Iss 3, Pp 367-376 (2021)
Background and Purpose CD40 and CD40 ligand (CD40L) are costimulatory molecules of the tumor necrosis factor receptor superfamily and well known for their involvement in inflammatory diseases: atherosclerotic mouse models with disrupted CD40 signalli
Externí odkaz:
https://doaj.org/article/a59fad5770eb4319b4cb7cdafcbcb201
Autor:
Josie Carmichael, Hassan Fadavi, Fukashi Ishibashi, Susan Howard, Andrew J. M. Boulton, Angela C. Shore, Mitra Tavakoli
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
ObjectiveScreening for diabetic peripheral neuropathy (DPN) is essential for early detection and timely intervention. Quantitative assessment of small nerve fiber damage is key to the early diagnosis and assessment of its progression. Corneal confoca
Externí odkaz:
https://doaj.org/article/30fe9f975c1440479683d5afd2b9ffab
Autor:
Kim M. Gooding, Chrysta Lienczewski, Massimo Papale, Niina Koivuviita, Marlena Maziarz, Anna-Maria Dutius Andersson, Kanishka Sharma, Paola Pontrelli, Alberto Garcia Hernandez, Julie Bailey, Kay Tobin, Virva Saunavaara, Anna Zetterqvist, David Shelley, Irvin Teh, Claire Ball, Sapna Puppala, Mark Ibberson, Anil Karihaloo, Kaj Metsärinne, Rosamonde E. Banks, Peter S. Gilmour, Michael Mansfield, Mark Gilchrist, Dick de Zeeuw, Hiddo J. L. Heerspink, Pirjo Nuutila, Matthias Kretzler, Matthew Welberry Smith, Loreto Gesualdo, Dennis Andress, Nicolas Grenier, Angela C. Shore, Maria F. Gomez, Steven Sourbron, for the BEAt-DKD consortium
Publikováno v:
BMC Nephrology, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background Diabetic kidney disease (DKD) remains one of the leading causes of premature death in diabetes. DKD is classified on albuminuria and reduced kidney function (estimated glomerular filtration rate (eGFR)) but these have modest value
Externí odkaz:
https://doaj.org/article/e94cbf7fb6ec48ce9d18b5b1e307048f
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
The incidence of both type 1 and type 2 diabetes is increasing worldwide. Diabetic peripheral neuropathy (DPN) is among the most distressing and costly of all the chronic complications of diabetes and is a cause of significant disability and poor qua
Externí odkaz:
https://doaj.org/article/26e522a149f74c43b7acdffb9acad933
Autor:
Thomas J. E. Hubbard, Alexander P. Dudgeon, Douglas J. Ferguson, Angela C. Shore, Nicholas Stone
Publikováno v:
Translational Biophotonics, Vol 3, Iss 2, Pp n/a-n/a (2021)
Abstract Breast conserving surgery (BCS) for breast cancer aims for optimal oncological results with minimal tissue excision. Positive margins due to insufficient resection results in significant numbers of patients requiring re‐excision, which cou
Externí odkaz:
https://doaj.org/article/ecd5ffa98e0d4da28ec70fc4278f880d
Publikováno v:
Practical Laboratory Medicine, Vol 15, Iss , Pp - (2019)
Background: Increasing albumin to creatinine ratio (ACR) within the normal range is a risk factor for cardiovascular disease in the general population. Clinical and epidemiological studies often store urine samples for long durations prior to ACR ass
Externí odkaz:
https://doaj.org/article/fee915cd2bed42c2acbe997b25152381
Autor:
Kunihiko Aizawa, Francesco Casanova, David M. Mawson, Kim M. Gooding, W. David Strain, Phillip E. Gates, Gerd Östling, Faisel Khan, Helen M. Colhoun, Carlo Palombo, Kim H. Parker, Jan Nilsson, Angela C. Shore, Alun D. Hughes
Publikováno v:
Artery Research, Vol 24 (2018)
Background: Central haemodynamic parameters derived from reservoir pressure analysis (RPA-parameters) exhibit prognostic utility. Alterations in reservoir function could have an unfavourable influence on target organs, such as the kidneys. We determi
Externí odkaz:
https://doaj.org/article/a4607fbe2d4a472797443fdfb62bf869