SARS-CoV-2 anti-spike antibody titres after vaccination with BNT162b2 in naïve and previously infected individuals

Autor: Andrea Lombardi, Dario Consonni, Massimo Oggioni, Patrizia Bono, Sara U. Renteria, Alessandra Piatti, Angela C. Pesatori, Silvana Castaldi, Antonio Muscatello, Luciano Riboldi, Ferruccio Ceriotti, Alessandra Bandera, Andrea Gori

Publikováno v: Journal of Infection and Public Health, Vol 14, Iss 8, Pp 1120-1122 (2021)

Great expectations are placed in vaccines against COVID-19 to control the pandemic. We reviewed the antibody titres in a cohort of healthcare workers (HCWs) vaccinated with BNT162b2 to assess the influence of a previous infection on them. We stratifi

Externí odkaz: https://doaj.org/article/376ea85e60914b64908bc1107d776ee7

Genetic and epigenetic intratumor heterogeneity impacts prognosis of lung adenocarcinoma

Autor: Xing Hua, Wei Zhao, Angela C. Pesatori, Dario Consonni, Neil E. Caporaso, Tongwu Zhang, Bin Zhu, Mingyi Wang, Kristine Jones, Belynda Hicks, Lei Song, Joshua Sampson, David C. Wedge, Jianxin Shi, Maria Teresa Landi

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)

Many tumors are known to be heterogeneous. Here, the authors examined multiple samples from 84 patients with lung adenocarcinoma and demonstrate that the intratumor heterogeneity of methylation and copy number associates with poor prognosis.

Externí odkaz: https://doaj.org/article/f79d02735f92481887e53a5ea22a061f

Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk

Autor: Xuemei Ji, Yohan Bossé, Maria Teresa Landi, Jiang Gui, Xiangjun Xiao, David Qian, Philippe Joubert, Maxime Lamontagne, Yafang Li, Ivan Gorlov, Mariella de Biasi, Younghun Han, Olga Gorlova, Rayjean J. Hung, Xifeng Wu, James McKay, Xuchen Zong, Robert Carreras-Torres, David C. Christiani, Neil Caporaso, Mattias Johansson, Geoffrey Liu, Stig E. Bojesen, Loic Le Marchand, Demetrios Albanes, Heike Bickeböller, Melinda C. Aldrich, William S. Bush, Adonina Tardon, Gad Rennert, Chu Chen, M. Dawn Teare, John K. Field, Lambertus A. Kiemeney, Philip Lazarus, Aage Haugen, Stephen Lam, Matthew B. Schabath, Angeline S. Andrew, Hongbing Shen, Yun-Chul Hong, Jian-Min Yuan, Pier A. Bertazzi, Angela C. Pesatori, Yuanqing Ye, Nancy Diao, Li Su, Ruyang Zhang, Yonathan Brhane, Natasha Leighl, Jakob S. Johansen, Anders Mellemgaard, Walid Saliba, Christopher Haiman, Lynne Wilkens, Ana Fernandez-Somoano, Guillermo Fernandez-Tardon, Erik H. F. M. van der Heijden, Jin Hee Kim, Juncheng Dai, Zhibin Hu, Michael P. A. Davies, Michael W. Marcus, Hans Brunnström, Jonas Manjer, Olle Melander, David C. Muller, Kim Overvad, Antonia Trichopoulou, Rosario Tumino, Jennifer Doherty, Gary E. Goodman, Angela Cox, Fiona Taylor, Penella Woll, Irene Brüske, Judith Manz, Thomas Muley, Angela Risch, Albert Rosenberger, Kjell Grankvist, Mikael Johansson, Frances Shepherd, Ming-Sound Tsao, Susanne M. Arnold, Eric B. Haura, Ciprian Bolca, Ivana Holcatova, Vladimir Janout, Milica Kontic, Jolanta Lissowska, Anush Mukeria, Simona Ognjanovic, Tadeusz M. Orlowski, Ghislaine Scelo, Beata Swiatkowska, David Zaridze, Per Bakke, Vidar Skaug, Shanbeh Zienolddiny, Eric J. Duell, Lesley M. Butler, Woon-Puay Koh, Yu-Tang Gao, Richard Houlston, John McLaughlin, Victoria Stevens, David C. Nickle, Ma’en Obeidat, Wim Timens, Bin Zhu, Lei Song, María Soler Artigas, Martin D. Tobin, Louise V. Wain, Fangyi Gu, Jinyoung Byun, Ahsan Kamal, Dakai Zhu, Rachel F. Tyndale, Wei-Qi Wei, Stephen Chanock, Paul Brennan, Christopher I. Amos

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)

The chromosome 15q25.1 locus is a leading susceptibility region for lung cancer. Here, the authors interrogate three GWAS cohorts with 42,901 individuals to investigate potential pathological pathways such as gated channel activity and neuroactive li

Externí odkaz: https://doaj.org/article/29ca3423d6cf4628986d3e91e5d94ada

Data from A Gene Expression Signature from Peripheral Whole Blood for Stage I Lung Adenocarcinoma

Autor: Maria Teresa Landi, Phil R. Taylor, Neil E. Caporaso, Joanna Shih, Sholom Wacholder, Pier Alberto Bertazzi, Angela C. Pesatori, Dario Consonni, Andrew W. Bergen, Alisa M. Goldstein, Chaoyu Wang, Hua Su, Nan Hu, Melissa Rotunno

Affordable early screening in subjects with high risk of lung cancer has great potential to improve survival from this deadly disease. We measured gene expression from lung tissue and peripheral whole blood (PWB) from adenocarcinoma cases and control

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d6e5b9280a41f85f1ee818026ad0c77
https://doi.org/10.1158/1940-6207.c.6545214

Supplementary Methods, Figure 1, Tables 1-6 from Inherited Variation at Chromosome 12p13.33, Including RAD52, Influences the Risk of Squamous Cell Lung Carcinoma

Autor: Maria Teresa Landi, Richard S. Houlston, Christopher I. Amos, Stephen J. Chanock, Neil E. Caporaso, Pier Alberto Bertazzi, Margaret R. Spitz, Michael Thun, Demetrius Albanes, Qiong Dong, Wei Chen, Zhaoming Wang, Timothy Eisen, Marc Henrion, Peter Broderick, William Wheeler, Peng Li, Dario Consonni, Angela C. Pesatori, Yufei Wang, Melissa Rotunno, Nilanjan Chatterjee, Jianxin Shi

PDF file - 386K

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::975b45c80cbdc49b4662e1002ec5b80e
https://doi.org/10.1158/2159-8290.22528677