Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Angela B. V. Quach"'
Publikováno v:
Analytical Chemistry. 94:4039-4047
Viral-based systems are a popular delivery method for introducing exogenous genetic material into mammalian cells. Unfortunately, the preparation of lentiviruses containing the machinery to edit the cells is labor-intensive, with steps requiring opti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6edd644aecc72b1a098a11e5fb65b59
https://doi.org/10.1021/acs.analchem.1c05227
https://doi.org/10.1021/acs.analchem.1c05227
The process of generating a stable knockout cell line is a complex process that can take several months to complete. In this work, we introduce a microfluidic method that is capable of isolating single cells, selecting successful edited clones, and e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d87b03cf939551908ed531186082104b
https://doi.org/10.1101/2020.01.24.908202
https://doi.org/10.1101/2020.01.24.908202
Publikováno v:
Lab on a Chip. 18:2300-2312
Gene-editing techniques such as RNA-guided endonuclease systems are becoming increasingly popular for phenotypic screening. Such screens are normally conducted in arrayed or pooled formats. There has been considerable interest in recent years to find
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3177260ba78a34af8cf22f205e8617ae
https://doi.org/10.1039/c8lc00470f
https://doi.org/10.1039/c8lc00470f
Publikováno v:
Biomicrofluidics
Acclaimed as one of the biggest scientific breakthroughs, the technology of CRISPR has brought significant improvement in the biotechnological spectrum—from editing genetic defects in diseases for gene therapy to modifying organisms for the product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f68e60fd232ff9d4b2d832bed769fb9c
https://doi.org/10.1063/5.0029846
https://doi.org/10.1063/5.0029846
Publikováno v:
Small. 16:2070190
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77f02c84dcbf5aeeb278cd752bb2f2fc
https://doi.org/10.1002/smll.202070190
https://doi.org/10.1002/smll.202070190
Publikováno v:
Small. 16:2002400
Generating a stable knockout cell line is a complex process that can take several months to complete. In this work, a microfluidic method that is capable of isolating single cells in droplets, selecting successful edited clones, and expansion of thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfbfd6a18bf4df4acc030c6a66236925
https://doi.org/10.1002/smll.202002400
https://doi.org/10.1002/smll.202002400