Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Angela Mally"'
Autor:
Shihori Tanabe, Jason O’Brien, Knut Erik Tollefsen, Youngjun Kim, Vinita Chauhan, Carole Yauk, Elizabeth Huliganga, Ruthann A. Rudel, Jennifer E. Kay, Jessica S. Helm, Danielle Beaton, Julija Filipovska, Iva Sovadinova, Natalia Garcia-Reyero, Angela Mally, Sarah Søs Poulsen, Nathalie Delrue, Ellen Fritsche, Karsta Luettich, Cinzia La Rocca, Hasmik Yepiskoposyan, Jördis Klose, Pernille Høgh Danielsen, Maranda Esterhuizen, Nicklas Raun Jacobsen, Ulla Vogel, Timothy W. Gant, Ian Choi, Rex FitzGerald
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are formed as a result of natural cellular processes, intracellular signaling, or as adverse responses associated with diseases or exposure to oxidizing chemical and non-chemical stres
Externí odkaz:
https://doaj.org/article/6e4603ffc4664fc2936ec3f4a2a4f907
Autor:
Angela Mally, Sebastian Jarzina
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
In line with recent OECD activities on the use of AOPs in developing Integrated Approaches to Testing and Assessment (IATAs), it is expected that systematic mapping of AOPs leading to systemic toxicity may provide a mechanistic framework for the deve
Externí odkaz:
https://doaj.org/article/05865d91401541fd95d46eca7c68c700
Autor:
Sebastian Jarzina, Stefano Di Fiore, Bernhard Ellinger, Pia Reiser, Sabrina Frank, Markus Glaser, Jiaqing Wu, Femke J. Taverne, Nynke I. Kramer, Angela Mally
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Application of adverse outcome pathways (AOP) and integration of quantitative in vitro to in vivo extrapolation (QIVIVE) may support the paradigm shift in toxicity testing to move from apical endpoints in test animals to more mechanism-based in vitro
Externí odkaz:
https://doaj.org/article/702a50c3a5af4d85a1746fc787ed859f
Autor:
Cynthia Adaku Chilaka, Jude Ejikeme Obidiegwu, Augusta Chinenye Chilaka, Olusegun Oladimeji Atanda, Angela Mally
Publikováno v:
Toxins, Vol 14, Iss 7, p 442 (2022)
Food safety problems are a major hindrance to achieving food security, trade, and healthy living in Africa. Fungi and their secondary metabolites, known as mycotoxins, represent an important concern in this regard. Attempts such as agricultural, stor
Externí odkaz:
https://doaj.org/article/0d84bc72d88c4e5d8c097a20ab89c480
Autor:
EFSA Panel on Contaminants in the Food Chain (CONTAM), Dieter Schrenk, Laurent Bodin, James Kevin Chipman, Jesús del Mazo, Bettina Grasl‐Kraupp, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Jean‐Charles Leblanc, Carlo Stefano Nebbia, Elsa Nielsen, Evangelia Ntzani, Annette Petersen, Salomon Sand, Tanja Schwerdtle, Christiane Vleminckx, Heather Wallace, Jan Alexander, Chiara Dall'Asta, Angela Mally, Manfred Metzler, Marco Binaglia, Zsuzsanna Horváth, Hans Steinkellner, Margherita Bignami
Publikováno v:
EFSA Journal, Vol 18, Iss 5, Pp n/a-n/a (2020)
Abstract The European Commission asked EFSA to update their 2006 opinion on ochratoxin A (OTA) in food. OTA is produced by fungi of the genus Aspergillus and Penicillium and found as a contaminant in various foods. OTA causes kidney toxicity in diffe
Externí odkaz:
https://doaj.org/article/dab537cc580d4816a8595f9f78786ac2
Autor:
Michael Aschner, Monica M.B. Paoliello, Jose L. Domingo, Demetrios A. Spandidos, Angela Mally, Heather M Wallace, Valerii N. Rakitskii, Thomas Hartung, Aristides Tsatsakis
Publikováno v:
Toxicology Reports, Vol 7, Iss , Pp 1607- (2020)
Externí odkaz:
https://doaj.org/article/a5cc3864741b4e6abc5977bed5769006
Publikováno v:
Toxins, Vol 13, Iss 8, p 587 (2021)
Ochratoxin A (OTA) is a widespread food contaminant, with exposure estimated to range from 0.64 to 17.79 ng/kg body weight (bw) for average consumers and from 2.40 to 51.69 ng/kg bw per day for high consumers. Current exposure estimates are, however,
Externí odkaz:
https://doaj.org/article/72196b70d9b84d7cb4f9b0e1849ec03b
Autor:
Katja Merches, Leonie Breunig, Julia Fender, Theresa Brand, Vanessa Bätz, Svenja Idel, Laxmikanth Kollipara, Yvonne Reinders, Albert Sickmann, Angela Mally, Kristina Lorenz
Publikováno v:
Archives of Toxicology. 96:2341-2360
Remdesivir is a prodrug of a nucleoside analog and the first antiviral therapeutic approved for coronavirus disease. Recent cardiac safety concerns and reports on remdesivir-related acute kidney injury call for a better characterization of remdesivir
Autor:
Gerhard Eisenbrand, Matthias Baum, Alexander T. Cartus, Patrick Diel, Karl-Heinz Engel, Barbara Engeli, Bernd Epe, Tilman Grune, Sabine Guth, Dirk Haller, Volker Heinz, Michael Hellwig, Jan G. Hengstler, Thomas Henle, Hans-Ulrich Humpf, Henry Jäger, Hans-Georg Joost, Sabine Kulling, Dirk W. Lachenmeier, Alfonso Lampen, Marcel Leist, Angela Mally, Doris Marko, Ute Nöthlings, Elke Röhrdanz, Angelika Roth, Joachim Spranger, Richard Stadler, Stefan Vieths, Wim Wätjen, Pablo Steinberg
Publikováno v:
Archives of Toxicology. 96:1905-1914
Subsequent to the dietary uptake of nitrate/nitrite in combination with acetaldehyde/ethanol, combination effects resulting from the sustained endogenous exposure to nitrite and acetaldehyde may be expected. This may imply locoregional effects in the
Publikováno v:
Archives of Toxicology. 96:1423-1435
Recent analyses conducted by German official food control reported detection of the aromatic amides N-(2,4-dimethylphenyl)acetamide (NDPA), N-acetoacetyl-m-xylidine (NAAX) and 3-hydroxy-2-naphthanilide (Naphthol AS) in cold water extracts from certai