Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Angela, Wilks"'
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT Pseudomonas aeruginosa is a versatile opportunistic pathogen requiring iron for its survival and virulence within the host. The ability to switch to heme as an iron source and away from siderophore uptake provides an advantage in chronic inf
Externí odkaz:
https://doaj.org/article/02dfa482a5784a609f8d6e8e6ac13f51
Autor:
Tra-My Hoang, Weiliang Huang, Jonathan Gans, Jacob Weiner, Evan Nowak, Mariette Barbier, Angela Wilks, Maureen A. Kane, Amanda G. Oglesby
Publikováno v:
mSphere, Vol 8, Iss 5 (2023)
ABSTRACT Pseudomonas aeruginosa is an opportunistic pathogen that requires iron for growth and virulence, yet this nutrient is sequestered by the innate immune system during infection. When iron is limiting, P. aeruginosa expresses the PrrF1 and PrrF
Externí odkaz:
https://doaj.org/article/253686b6df8741d095c0c3bf7398bace
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The ability to obtain purified biliverdin IX (BVIX) isomers other than the commercially available BVIXα is limited due to the low yields obtained by the chemical coupled oxidation of heme. Chemical oxidation requires toxic chemicals, has very poor B
Externí odkaz:
https://doaj.org/article/07e7d00198a243bdb1ea7bae2ff5fabe
Autor:
Weiliang Huang, Angela Wilks
Publikováno v:
BMC Microbiology, Vol 17, Iss 1, Pp 1-8 (2017)
Abstract Background Pseudomonas aeruginosa is a model organism for the study of quorum sensing, biofilm formation, and also leading cause of nosocomial infections in immune compromised patients. As such P. aeruginosa is one of the most well studied o
Externí odkaz:
https://doaj.org/article/10e495cfd5924cfb8aea603600a2106b
Autor:
Inmaculada Martínez Sanz, Biljana Stojkovska, Angela Wilks, Jonathan Horne, Ali R. Ahmadi, Tatiana Ustinova
Publikováno v:
The Journal of Engineering (2019)
This study describes the technical principles behind the Power Potential innovation project in Great Britain (GB). The project aims to enable distributed energy resources (DERs) connected to the distribution network to provide services to the transmi
Externí odkaz:
https://doaj.org/article/bd3fec8608bd451f8a364747b05fdf03
Autor:
Tra-My Hoang, Weiliang Huang, Jonathan Gans, Evan Nowak, Mariette Barbier, Angela Wilks, Maureen A. Kane, Amanda G. Oglesby
Pseudomonas aeruginosais an opportunistic pathogen that requires iron for growth and virulence, yet this nutrient is sequestered by the innate immune system during infection. When iron is limiting,P. aeruginosaexpresses the PrrF1 and PrrF2 small regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b1189e879f4dc57c7523246430fac39
https://doi.org/10.1101/2023.01.19.524833
https://doi.org/10.1101/2023.01.19.524833
Autor:
Kyle C. Kihn, Richard T. Bradshaw, Tyree Wilson, Daniel Deredge, Lucy R. Forrest, Patrick L. Wintrode, Angela Wilks, Ally K. Smith
Publikováno v:
Biophys J
The cytoplasmic heme binding protein from Pseudomonas aeruginosa, PhuS, plays two essential roles in regulating heme uptake and iron homeostasis. First, PhuS shuttles exogenous heme to heme oxygenase (HemO) for degradation and iron release. Second, P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ecd9bee1062697cfde6f77f85fac48
https://doi.org/10.1016/j.bpj.2021.11.010
https://doi.org/10.1016/j.bpj.2021.11.010
Publikováno v:
Biochemistry. 60:689-698
Iron is an essential micronutrient for the survival and virulence of the bacterial pathogen Pseudomonas aeruginosa. To overcome iron withholding and successfully colonize a host, P. aeruginosa uses a variety of mechanisms to acquire iron, including t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::197bf1488c0ba2af13acee39c2a7ba08
https://doi.org/10.1021/acs.biochem.0c00895
https://doi.org/10.1021/acs.biochem.0c00895
Autor:
Maureen A. Kane, Jordan D. Pritts, Abdulafeez A. Oluyadi, Angela Wilks, Sarah L. J. Michel, Geoffrey D. Shimberg, Weiliang Huang
Publikováno v:
Biochemistry
Cleavage and polyadenylation specificity factor 30 (CPSF30) is a zinc finger protein that regulates pre-mRNA processing. CPSF30 contains five CCCH domains and one CCHC domain and recognizes two conserved 3' pre-mRNA sequences: an AU hexamer and a U-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f7c09f9043b8c1a0bbe388730ae1026
https://doi.org/10.1021/acs.biochem.0c00940
https://doi.org/10.1021/acs.biochem.0c00940
Autor:
Fengtian Xue, Yong Ai, Garrick Centola, Kellie Hom, Angela Wilks, Daniel Deredge, Alecia T. Dent
Publikováno v:
ACS Infectious Diseases. 6:2073-2085
Pseudomonas aeruginosa is an opportunistic bacterium that causes life-threatening infections in immunocompromised patients. In infection, it uses heme as a primary iron source and senses the availability of exogenous heme through the heme assimilatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41dd98cba718dc94815ac640916b6eac
https://doi.org/10.1021/acsinfecdis.0c00138
https://doi.org/10.1021/acsinfecdis.0c00138