Asthma severity: the patient’s point of view

Autor: Gabriella Guarnieri, Bianca Olivieri, Manuela Latorre, Angela Rizzi, Francesco Blasi, Giorgio Walter Canonica, Enrico Heffler, Pierluigi Paggiaro, Gianenrico Senna, Marco Caminati

Publikováno v: European Clinical Respiratory Journal, Vol 11, Iss 1 (2024)

Objective Initiated by the Severe Asthma Network Italy (SANI), this study aims to explore asthma patients’ perceptions of disease severity, differentiating between mild and severe asthma. The objective is to identify factors influencing tailored tr

Externí odkaz: https://doaj.org/article/6501b9ac351f4bb596c3ac928d865be4

The Emerging Role of Innate Lymphoid Cells (ILCs) and Alarmins in Celiac Disease: An Update on Pathophysiological Insights, Potential Use as Disease Biomarkers, and Therapeutic Implications

Autor: Angela Rizzi, Mario Di Gioacchino, Luca Gammeri, Riccardo Inchingolo, Raffaella Chini, Francesca Santilli, Eleonora Nucera, Sebastiano Gangemi

Publikováno v: Cells, Vol 12, Iss 14, p 1910 (2023)

Celiac disease (CD) is an intestinal disease that develops in genetically predisposed individuals and is triggered by the ingestion of gluten. CD was considered a Th1-disease. Today, the role of Th17, IL-21, and IL-17A lymphocytes is well known. Infl

Externí odkaz: https://doaj.org/article/5eff4416d5a3497c9c5265423247bbce

Severe asthma: One disease and multiple definitions

Autor: Diego Bagnasco, MD, PhD, Pierluigi Paggiaro, MD, Manuela Latorre, MD, Chiara Folli, BS, Elisa Testino, MD, Arianna Bassi, MD, Manlio Milanese, MD, Enrico Heffler, MD, Andrea Manfredi, Anna Maria Riccio, BS, Laura De Ferrari, BS, Francesco Blasi, Rikki Frank Canevari, MD, Giorgio Walter Canonica, MD, Giovanni Passalacqua, MD, Gabriella Guarnieri, Vincenzo Patella, Foschino Barbaro Maria Pia, Giovanna Elisiana Carpagnano, Anna del Colle, Giulia Scioscia, Pelaia Gerolamo, Francesca Puggioni, Francesca Racca, Elisabetta Favero, Sandra Iannacone, Eleonora Savi, Marcello Montagni, Gianna Camiciottoli, Chiara Allegrini, Carlo Lombardi, Giuseppe Spadaro, Caterina Detoraki, Francesco Menzella, Carla Galeone, Patrizia Ruggiero, Monna Rita Yacoub, Alvise Berti, Nicola Scichilone, Carmen Durante, Maria Teresa Costantino, Chiara Roncallo, Mariachiara Braschi, Alice D’Adda, Erminia Ridolo, Massimo Triggiani, Roberta Parente, D’Amato Maria, Maria Vittoria Verrillo, Giovanni Rolla, Luisa Brussino, Agata Valentina Frazzetto, Zappa Maria Cristina, Marianna Lilli, Nunzio Crimi, Marco Bonavia, Angelo Guido Corsico, Amelia Grosso, Stefano Del Giacco, Margherita Deidda, Luisa Ricciardi, Stefania Isola, Francesca Cicero, Giuliana Amato, Federica Vita, Antonio Spanevello, Patrizia Pignatti, Francesca Cherubino, Dina Visca, Fabio Luigi Massimo Ricciardolo, Vitina Maria Anna Carriero, Francesca Bertolini, Pierachille Santus, Roberta Barlassina, Andrea Airoldi, Giuseppe Guida, Nucera Eleonora, Arianna Aruanno, Angela Rizzi, Cristiano Caruso, Stefania Colantuono, Gianenrico Senna, Marco Caminati, Alessandra Arcolaci, Andrea Vianello, Fulvia Chieco Bianchi, Maria Rita Marchi, Stefano Centanni, Simone Luraschi, Silvia Ruggeri, Rocco Rinaldo, Elena Parazzini, Cecilia Calabrese, Martina Flora, Lorenzo Cosmi, Linda Di Pietro, Enrico Maggi, Laura Pini, Luigi Macchia, Danilo Di Bona, Luca Richeldi, Carola Condoluci, Leonello Fuso, Matteo Bonini, Alessandro Farsi, Giulia Carli, Paolo Montuschi, Giuseppe Santini, Maria Elisabetta Conte, Elisa Turchet, Carlo Barbetta, Francesco Mazza, Simona D’Alo, Stefano Pucci, Maria Filomena Caiaffa, Elena Minenna, Luciana D'Elia, Carlo Pasculli, Vittorio Viviano, Paolo Tarsia, Joyce Rolo, Mariacarmela Di Proietto, Salvatore Lo Cicero

Publikováno v: World Allergy Organization Journal, Vol 14, Iss 11, Pp 100606- (2021)

Introduction: There is, so far, no universal definition of severe asthma. This definition usually relies on: number of exacerbations, inhaled therapy, need for oral corticosteroids, and respiratory function. The use of such parameters varies in the d

Externí odkaz: https://doaj.org/article/8bd465ece0db4a60b1326728338e4570

Contrast Medium Hypersensitivity: A Large Italian Study with Long-Term Follow-Up

Autor: Eleonora Nucera, Giuseppe Parrinello, Sebastiano Gangemi, Alessandro Buonomo, Arianna Aruanno, Franziska Michaela Lohmeyer, Riccardo Inchingolo, Angela Rizzi

Publikováno v: Biomedicines, Vol 10, Iss 4, p 759 (2022)

Hypersensitivity reactions (HRs) to contrast media (CM) are a major problem. We compared differences of HRs to iodinated contrast media (ICM) versus gadolinium-based contrast media (GBCM), collecting data on prevalence, type, latency and severity. Se

Externí odkaz: https://doaj.org/article/c010b712aa4b45089a4c252d97a9f68d

Functional interplay between NF-κB-inducing kinase and c-Abl kinases limits response to Aurora inhibitors in multiple myeloma

Autor: Laura Mazzera, Manuela Abeltino, Guerino Lombardi, Anna Maria Cantoni, Roberto Ria, Micaela Ricca, Ilaria Saltarella, Valeria Naponelli, Federica Maria Angela Rizzi, Roberto Perris, Attilio Corradi, Angelo Vacca, Antonio Bonati, Paolo Lunghi

Publikováno v: Haematologica, Vol 104, Iss 12 (2019)

Considering that Aurora kinase inhibitors are currently under clinical investigation in hematologic cancers, the identification of molecular events that limit the response to such agents is essential for enhancing clinical outcomes. Here, we discover

Externí odkaz: https://doaj.org/article/9af9f48142a54c6ea530496b153bde16