Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Angela, Rigopoulos"'
Autor:
Christian W. Wichmann, Yit Wooi Goh, Adam C. Parslow, Angela Rigopoulos, Nancy Guo, Andrew M. Scott, Uwe Ackermann, Jonathan M. White
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 5, Iss 1, Pp 1-20 (2020)
Abstract Background Targeted therapy of HER2 positive breast cancer has led to clinical success in some cases with primary and secondary resistance being major obstacles. Due to the substantial involvement of mTOR kinase in cell growth and proliferat
Externí odkaz:
https://doaj.org/article/46ec3ba522d9491aa0fbc6b52e05ab56
Autor:
Christian Wichmann, Andrew Scott, Fiona Scott, Ingrid Burvenich, Alexander McDonald, Nancy Guo, Angela Rigopoulos, Raul Soikes, Steven Angelides, Reinhard von Roemeling
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/01b02f2da1a94413b01d9c610d15a554
Autor:
Mercedes Dávalos-Salas, Magdalene K. Montgomery, Camilla M. Reehorst, Rebecca Nightingale, Irvin Ng, Holly Anderton, Sheren Al-Obaidi, Analia Lesmana, Cameron M. Scott, Paul Ioannidis, Hina Kalra, Shivakumar Keerthikumar, Lars Tögel, Angela Rigopoulos, Sylvia J. Gong, David S. Williams, Prusoth Yoganantharaja, Kim Bell-Anderson, Suresh Mathivanan, Yann Gibert, Scott Hiebert, Andrew M. Scott, Matthew J. Watt, John M. Mariadason
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Histone deacetylase 3 (HDAC3) is a regulator of lipid homeostasis in several tissues, however, its role in intestinal lipid metabolism was not yet known. Here the authors study intestine specific HDAC3 knock out mice and report that these animals hav
Externí odkaz:
https://doaj.org/article/517f7ab37ce74aff9258c9ede119de9a
Autor:
Tanmay M. Shekhar, Ingrid J. G. Burvenich, Michael A. Harris, Angela Rigopoulos, Damien Zanker, Alex Spurling, Belinda S. Parker, Carl R. Walkley, Andrew M. Scott, Christine J. Hawkins
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-18 (2019)
Abstract Background Current therapies fail to cure over a third of osteosarcoma patients and around three quarters of those with metastatic disease. “Smac mimetics” (also known as “IAP antagonists”) are a new class of anti-cancer agents. Prev
Externí odkaz:
https://doaj.org/article/99b7b10e16ee4f3fadd02b3425b1778e
Autor:
Catherine G. Fitzgerald Dickmann, Alexander F. McDonald, Nhi Huynh, Angela Rigopoulos, Zhanqi Liu, Nancy Guo, Laura D. Osellame, Michael A. Gorman, Michael W. Parker, Hui K. Gan, Andrew M. Scott, Uwe Ackermann, Ingrid J. G. Burvenich, Jonathan M. White
Publikováno v:
Chemical Communications. 59:3126-3129
A fluorine-18 labelled probe was developed to target bromodomain and extraterminal (BET) proteins for molecular imaging of cancer with positron emission tomography.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3bfcc706e9c3c268878945c2b903e77
https://doi.org/10.1039/d2cc04813b
https://doi.org/10.1039/d2cc04813b
Autor:
Puey-Ling Chia, Sagun Parakh, Ming-Sound Tsao, Nhu-An Pham, Hui K. Gan, Diana Cao, Ingrid J. G. Burvenich, Angela Rigopoulos, Edward B. Reilly, Thomas John, Andrew M. Scott
Publikováno v:
Pharmaceuticals, Vol 13, Iss 10, p 289 (2020)
Epidermal growth factor receptor (EGFR) is highly overexpressed in malignant mesothelioma (MM). MAb806 is a novel anti-EGFR antibody that selectively targets a tumor-selective epitope. MAb806-derived antibody drug conjugates (ADCs), ABT-414, ABBV-221
Externí odkaz:
https://doaj.org/article/fe2d9f07976d49e8880342331b1b8d0a
Autor:
Katie S. Ardipradja, Christian W. Wichmann, Kevin Hickson, Angela Rigopoulos, Karen M. Alt, Hannah A. Pearce, Xiaowei Wang, Graeme O’Keefe, Andrew M. Scott, Karlheinz Peter, Christoph E. Hagemeyer, Uwe Ackermann
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 13; Pages: 6886
Positron emission tomography is the imaging modality of choice when it comes to the high sensitivity detection of key markers of thrombosis and inflammation, such as activated platelets. We, previously, generated a fluorine-18 labelled single-chain a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4120e7615a7101afc549ae2f830eb8a
Autor:
Christian W. Wichmann, Stan Poniger, Nancy Guo, Peter Roselt, Stacey E. Rudd, Paul S. Donnelly, Benjamin Blyth, Jessica Van Zuylekom, Angela Rigopoulos, Ingrid J.G. Burvenich, Laurence Morandeau, Shifaza Mohamed, Anna K. Nowak, Fiona Hegi-Johnson, Michael MacManus, Andrew M. Scott
Publikováno v:
Nuclear Medicine and Biology. :108351
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17b1d30333a59f08b6a7ecd831e3f1d5
https://doi.org/10.1016/j.nucmedbio.2023.108351
https://doi.org/10.1016/j.nucmedbio.2023.108351
Autor:
Wanping Geng, Christian Wichmann, Yit Wooi Goh, Angela Rigopoulos, Diana Cao, Linghui Li, Hui K Gan, Yan Lan, Nhi Huynh, Fiona Scott, Andrew M. Scott, Alexander Franklin McDonald, Anup Zutshi, Zhanqi Liu, Sylvia J. Gong, Nancy Guo, Uwe Ackermann, Ingrid Burvenich, Graeme O'Keefe
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 48:3075-3088
Τhis study aimed to optimize the 89Zr-radiolabelling of bintrafusp alfa investigational drug product and controls, and perform the in vitro and in vivo characterization of 89Zr-Df-bintrafusp alfa and 89Zr-Df-control radioconjugates. Bintrafusp alfa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b05231523021590b3963635bb631ad8
https://doi.org/10.1007/s00259-021-05251-0
https://doi.org/10.1007/s00259-021-05251-0
Synthesis and fluorine-18 radiolabeling of a phospholipid as a PET imaging agent for prostate cancer
Autor:
Margaret M. Centenera, Lisa M. Butler, Andrew J. Hoy, Johannes V. Swinnen, Jonathan M. White, Ganesh V. Raj, Uwe Ackermann, Yit Wooi Goh, Jonas Dehairs, Ingrid Burvenich, Kim H. Kwan, Andrew M. Scott, Angela Rigopoulos
Publikováno v:
Nucl Med Biol
INTRODUCTION: Altered lipid metabolism and subsequent changes in cellular lipid composition have been observed in prostate cancer cells, are associated with poor clinical outcome, and are promising targets for metabolic therapies. This study reports
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03036f38efdceae27a6ab86c5c9a563f
https://doi.org/10.1016/j.nucmedbio.2020.11.007
https://doi.org/10.1016/j.nucmedbio.2020.11.007