Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Angela, Oskamp"'
Autor:
Xuan He, Franziska Wedekind, Tina Kroll, Angela Oskamp, Simone Beer, Alexander Drzezga, Johannes Ermert, Bernd Neumaier, Andreas Bauer, David Elmenhorst
Publikováno v:
Frontiers in Physiology, Vol 10 (2020)
PurposeIn vivo imaging for the A1 adenosine receptors (A1ARs) with positron emission tomography (PET) using 8-cyclopentyl-3-(3-[18F]fluoropropyl)-1-propylxan- thine ([18F]CPFPX) has become an important tool for studying physiological processes quanti
Externí odkaz:
https://doaj.org/article/b84e31c0ec174ee7b0f089c221d3c2d4
Autor:
Tina Kroll, Nikola Kornadt-Beck, Angela Oskamp, David Elmenhorst, Chadi Touma, Rupert Palme, Andreas Bauer
Publikováno v:
Animals, Vol 11, Iss 3, p 710 (2021)
Since animal experiments cannot be completely avoided, the pain, suffering, and distress of laboratory animals must be minimized. To this end, a major prerequisite is reliable assessment of pain and distress. Usually, evaluation of animal welfare is
Externí odkaz:
https://doaj.org/article/948a2369b61446f3a26234bb079340db
Autor:
Daniela Schneider, Angela Oskamp, Marcus Holschbach, Bernd Neumaier, Andreas Bauer, Dirk Bier
Publikováno v:
Pharmaceuticals, Vol 12, Iss 2, p 57 (2019)
The prediction of in vivo clearance from in vitro metabolism models such as liver microsomes is an established procedure in drug discovery. The potentials and limitations of this approach have been extensively evaluated in the pharmaceutical sector;
Externí odkaz:
https://doaj.org/article/02ff415f50114e79a529e8148509d044
Autor:
Dirk Bier, Marcus H. Holschbach, Daniela Schneider, Angela Oskamp, Andreas Bauer, Bernd Neumaier
Publikováno v:
Nuclear medicine and biology 82-83, 1-8 (2020). doi:10.1016/j.nucmedbio.2019.12.001
Introduction The suitability of novel positron emission tomography (PET) radioligands for quantitative in vivo imaging is affected by various physicochemical and pharmacological parameters. In this study, the combined effect of binding affinity, lipo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7fad11eb4f0b02dfe453fd675a2ae02
https://doi.org/10.1016/j.nucmedbio.2019.12.001
https://doi.org/10.1016/j.nucmedbio.2019.12.001
Autor:
Diones Bueno, Partha Narayan Dey, Teresa Schacht, Christina Wolf, Verena Wüllner, Elena Morpurgo, Liliana Rojas-Charry, Lena Sessinghaus, Petra Leukel, Clemens Sommer, Konstantin Radyushkin, Michael K.E. Schäfer, Luise Florin, Jan Baumgart, Paul Stamm, Andreas Daiber, Guilherme Horta, Leonardo Nardi, Verica Vasic, Michael J. Schmeisser, Andrea Hellwig, Angela Oskamp, Andreas Bauer, Ruchika Anand, Andreas S. Reichert, Sandra Ritz, Gianluigi Nocera, Claire Jacob, Jonas Peper, Marion Silies, Katrin B. M. Frauenknecht, Axel Methner
Publikováno v:
bioRxiv beta (2021). doi:10.1101/2021.02.15.431234
Synaptic signaling depends on ATP generated by mitochondria. Due to extensive connectivity, the striatum is especially vulnerable to mitochondrial dysfunction and thus requires efficient mitochondrial quality control. We found that the neuronal calci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::123703cc702ef41157238c13c03b5664
https://doi.org/10.1101/2021.02.15.431234
https://doi.org/10.1101/2021.02.15.431234
Autor:
Karl Zilles, Angela Oskamp, Alexander Hawlitschka, Andreas Bauer, Franziska Wedekind, Andreas Wree, Markus Lang
Publikováno v:
Journal of Neuroscience Research. 96:75-86
Cerebral administration of botulinum neurotoxin A (BoNT-A) has been shown to improve disease-specific motor behavior in a rat model of Parkinson disease (PD). Since the dopaminergic system of the basal ganglia fundamentally contributes to motor funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::879a7c114c4de762f0042a45667bacb2
https://doi.org/10.1002/jnr.24110
https://doi.org/10.1002/jnr.24110
Publikováno v:
Chronobiology International. 34:866-875
Wakefulness and sleep are fundamental characteristics of the brain. We, therefore, hypothesized that transmitter systems contribute to their regulation and will exhibit circadian alterations.We assessed the concentration of various neurotransmitter r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a930a5489163602e6d7290c5df6bec
https://doi.org/10.1080/07420528.2017.1325370
https://doi.org/10.1080/07420528.2017.1325370
Autor:
Daniela, Schneider, Angela, Oskamp, Marcus, Holschbach, Bernd, Neumaier, Dirk, Bier, Andreas, Bauer
Publikováno v:
Nuclear medicine and biology.
The suitability of novel positron emission tomography (PET) radioligands for quantitative in vivo imaging is affected by various physicochemical and pharmacological parameters. In this study, the combined effect of binding affinity, lipophilicity, pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::85e41c167fb17a6c8a6c291347e8bcd8
https://pubmed.ncbi.nlm.nih.gov/31838339
https://pubmed.ncbi.nlm.nih.gov/31838339
Autor:
Daniela, Schneider, Angela, Oskamp, Marcus, Holschbach, Bernd, Neumaier, Andreas, Bauer, Dirk, Bier
Publikováno v:
Pharmaceuticals 12(2), 57 (2019). doi:10.3390/ph12020057
Pharmaceuticals, Vol 12, Iss 2, p 57 (2019)
Pharmaceuticals
Volume 12
Issue 2
Pharmaceuticals, Vol 12, Iss 2, p 57 (2019)
Pharmaceuticals
Volume 12
Issue 2
The prediction of in vivo clearance from in vitro metabolism models such as liver microsomes is an established procedure in drug discovery. The potentials and limitations of this approach have been extensively evaluated in the pharmaceutical sector
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a40f25de3a54ed238baff651fa9f68dd
https://hdl.handle.net/2128/22074
https://hdl.handle.net/2128/22074
Autor:
David Elmenhorst, Franziska Wedekind, Tina Kroll, Simone Beer, Heinz H. Coenen, Angela Oskamp, Johannes Ermert, Kristina Mertens, Eva-Maria Elmenhorst, Andreas Bauer
Publikováno v:
Journal of Sleep Research. 25:754-761
The metabotrophic subtype 5 glutamate receptor (mGluR5) plays a critical role in synaptic plasticity besides its involvement in numerous neurological disorders, such as depression. As mGluR5 availability in humans is altered in sleep deprivation, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063374171b405cfd9c606a684ca36e25
https://doi.org/10.1111/jsr.12432
https://doi.org/10.1111/jsr.12432