Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Angela, Mathison"'
Autor:
Michael D. Pisano, Fumou Sun, Yan Cheng, Deepak Parashar, Vivian Zhou, Xuefang Jing, Ramakrishna Sompallae, Jenica Abrudan, Michael T. Zimmermann, Angela Mathison, Siegfried Janz, Miles A. Pufall
Publikováno v:
Haematologica, Vol 108, Iss 12 (2023)
Multiple Myeloma (MM) is a plasma cell neoplasm originating in the bone marrow and is the second most common blood cancer in the United States. One challenge in understanding the pathogenesis of MM and improving treatment is a lack of immunocompetent
Externí odkaz:
https://doaj.org/article/932d2bf3280e4232aa9abb778270e6b4
Autor:
Angela Mathison, Thiago Milech De Assuncao, Nikita R Dsouza, Monique Williams, Michael T Zimmermann, Raul Urrutia, Gwen Lomberk
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0217452 (2020)
By reading the H3K9Me3 mark through their N-terminal chromodomain (CD), HP1 proteins play a significant role in cancer-associated processes, including cell proliferation, differentiation, chromosomal stability, and DNA repair. Here, we used a combina
Externí odkaz:
https://doaj.org/article/749eb96432a543119e511456baeb5162
Autor:
Gwen Lomberk, Yuna Blum, Rémy Nicolle, Asha Nair, Krutika Satish Gaonkar, Laetitia Marisa, Angela Mathison, Zhifu Sun, Huihuang Yan, Nabila Elarouci, Lucile Armenoult, Mira Ayadi, Tamas Ordog, Jeong-Heon Lee, Gavin Oliver, Eric Klee, Vincent Moutardier, Odile Gayet, Benjamin Bian, Pauline Duconseil, Marine Gilabert, Martin Bigonnet, Stephane Garcia, Olivier Turrini, Jean-Robert Delpero, Marc Giovannini, Philippe Grandval, Mohamed Gasmi, Veronique Secq, Aurélien De Reyniès, Nelson Dusetti, Juan Iovanna, Raul Urrutia
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Pancreatic ductal adenocarcinoma (PDAC) is a complex disease and its underlying epigenomic heterogeneity is not fully understood. Here, the authors utilize patient-derived PDAC xenografts to define the epigenomic landscape of PDAC, highlighting chrom
Externí odkaz:
https://doaj.org/article/ae929c3ce359431a8440a2e7a864fc2f
Autor:
Michael Zimmermann, Angela Mathison, Xuan Li, Elise Leverence, Davin Jensen, Guadalupe Esparza, Thiago Milech De Assuncao, Brian Smith, Brian Volkman, Gwen Lomberk, Raul Urrutia
The challenge of interpreting novel genetic variations in genomics is widespread. Previous studies have shown the role of KRAS mutations in heritable and somatic conditions, but more genetic variants have been observed than have been characterized. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49151cbe8996604699380bec0d0e3531
https://doi.org/10.21203/rs.3.rs-2883088/v1
https://doi.org/10.21203/rs.3.rs-2883088/v1
Autor:
Gwen Lomberk, Robert Huebert, Juan Iovanna, Navtej Buttar, Trace Christensen, Thiago M. de Assuncao, Asha Nair, Sarah Kossak, Monique Williams, Jennifer Bintz, Mckenna Missfeldt, Ann Salmonson, Angela Mathison
Detailed extended description of key methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fce7c44a1dcb57760425a2482fa5c5e
https://doi.org/10.1158/1541-7786.22515289
https://doi.org/10.1158/1541-7786.22515289
Autor:
Gwen Lomberk, Robert Huebert, Juan Iovanna, Navtej Buttar, Trace Christensen, Thiago M. de Assuncao, Asha Nair, Sarah Kossak, Monique Williams, Jennifer Bintz, Mckenna Missfeldt, Ann Salmonson, Angela Mathison
The current integrative pathobiologic hypothesis states that pancreatic cancer (PDAC) develops and progresses in response to an interaction between known oncogenes and downstream epigenomic regulators. Congruently, this study tests a new combinatoria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c55dbdd63f21b0231b85eb8ed839e75e
https://doi.org/10.1158/1541-7786.c.6541027.v1
https://doi.org/10.1158/1541-7786.c.6541027.v1
Autor:
Gwen Lomberk, Robert Huebert, Juan Iovanna, Navtej Buttar, Trace Christensen, Thiago M. de Assuncao, Asha Nair, Sarah Kossak, Monique Williams, Jennifer Bintz, Mckenna Missfeldt, Ann Salmonson, Angela Mathison
List of Antibodies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c6bad432d4c9172c183f4c939076ba
https://doi.org/10.1158/1541-7786.22515286.v1
https://doi.org/10.1158/1541-7786.22515286.v1
Autor:
Gwen Lomberk, Robert Huebert, Juan Iovanna, Navtej Buttar, Trace Christensen, Thiago M. de Assuncao, Asha Nair, Sarah Kossak, Monique Williams, Jennifer Bintz, Mckenna Missfeldt, Ann Salmonson, Angela Mathison
IC50 values for PDAC cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ce059e2249424196451f28bf8d5113
https://doi.org/10.1158/1541-7786.22515283.v1
https://doi.org/10.1158/1541-7786.22515283.v1
Autor:
Gwen Lomberk, Robert Huebert, Juan Iovanna, Navtej Buttar, Trace Christensen, Thiago M. de Assuncao, Asha Nair, Sarah Kossak, Monique Williams, Jennifer Bintz, Mckenna Missfeldt, Ann Salmonson, Angela Mathison
Fold change values for expression of individual DEGs found in response to combination treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fce26d59cfe082eda79676f9206b779
https://doi.org/10.1158/1541-7786.22515280
https://doi.org/10.1158/1541-7786.22515280
Autor:
Gwen Lomberk, Robert Huebert, Juan Iovanna, Navtej Buttar, Trace Christensen, Thiago M. de Assuncao, Asha Nair, Sarah Kossak, Monique Williams, Jennifer Bintz, Mckenna Missfeldt, Ann Salmonson, Angela Mathison
Additional data on clonogenic cell survival assay, cell viability, apoptosis, quantification of mitotic catastrophe and global decrease of H3K9me3 upon combination treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::781e2e1d104a33d8b3f0ddd171c3258a
https://doi.org/10.1158/1541-7786.22515292.v1
https://doi.org/10.1158/1541-7786.22515292.v1