Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Angel-M Cuesta"'
Autor:
Virginia Albiñana, Guillermo Giménez-Gallego, Angela García-Mato, Patricia Palacios, Lucia Recio-Poveda, Angel-M Cuesta, José-Luis Patier, Luisa-María Botella
Publikováno v:
TH Open, Vol 03, Iss 03, Pp e230-e243 (2019)
Hereditary hemorrhagic telangiectasia (HHT) is a vascular dysplasia characterized by recurrent and spontaneous epistaxis (nose bleeds), telangiectases on skin and mucosa, internal organ arteriovenous malformations, and dominant autosomal inheritance.
Externí odkaz:
https://doaj.org/article/02fb504621504e31997fc759d8991017
Autor:
Laura Lorente-Herraiz, Angel M. Cuesta, Lucía Recio-Poveda, Luisa M. Botella, Virginia Albiñana
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6163 (2024)
Pulmonary arteriovenous malformations (PAVMs) are vascular anomalies resulting in abnormal connections between pulmonary arteries and veins. In 80% of cases, PAVMs are present from birth, but clinical manifestations are rarely seen in childhood. Thes
Externí odkaz:
https://doaj.org/article/46b760980b3d4249acc0ee18550e8910
Autor:
Laura Lorente-Herraiz, Angel M. Cuesta, Jaime Granado, Lucía Recio-Poveda, Luisa-María Botella, Virginia Albiñana
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3952 (2024)
Cerebral cavernous malformation (CCM) or familial cavernomatosis is a rare, autosomal dominant, inherited disease characterized by the presence of vascular malformations consisting of blood vessels with an abnormal structure in the form of clusters.
Externí odkaz:
https://doaj.org/article/fb9ef1dd16b245ee9c5d1227bef580e7
Autor:
Angel M. Cuesta, Eunate Gallardo-Vara, Juan Casado-Vela, Lucía Recio-Poveda, Luisa-María Botella, Virginia Albiñana
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 8, p 4217 (2022)
Rare Diseases (RD) are defined by their prevalence in less than 5 in 10,000 of the general population. Considered individually, each RD may seem insignificant, but together they add up to more than 7000 different diseases. Research in RD is not attra
Externí odkaz:
https://doaj.org/article/37bf8baa0f37456ab8221b3d1bf57a19
Autor:
Isabel de Rojas-P, Virginia Albiñana, Lyudmyla Taranets, Lucía Recio-Poveda, Angel M. Cuesta, Nikita Popov, Thales Kronenberger, Luisa M. Botella
Publikováno v:
Cells, Vol 10, Iss 9, p 2313 (2021)
Von Hippel–Lindau disease (VHL) is a rare hereditary disease characterized by the predisposal to develop different types of highly vascularized tumors. VHL patients carry a VHL mutation that causes partial lack of functional VHL protein (pVHL) in a
Externí odkaz:
https://doaj.org/article/babeceef9360404993b67bea04a5eba7
Autor:
Sara Manzano, Alvaro Gutierrez-Uzquiza, Paloma Bragado, Angel M Cuesta, Carmen Guerrero, Almudena Porras
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 10018 (2021)
C3G (RAPGEF1) is a guanine nucleotide exchange factor (GEF) for GTPases from the Ras superfamily, mainly Rap1, although it also acts through GEF-independent mechanisms. C3G regulates several cellular functions. It is expressed at relatively high leve
Externí odkaz:
https://doaj.org/article/14314a8657fa4acaa48e01cb3f88b12b
Autor:
Till Acker, Boyan K. Garvalov, Amparo Acker-Palmer, Michael Kracht, Liane Jurida, Anne-Theres Henze, Angel M. Cuesta, Hui-Ke Jiao, Higinio Dopeso
Lung cancer is the leading cause of cancer-related death worldwide, in large part due to its high propensity to metastasize and to develop therapy resistance. Adaptive responses to hypoxia and epithelial–mesenchymal transition (EMT) are linked to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7485d2a734a8c47e9a3375d24ff9b8f6
https://doi.org/10.1158/0008-5472.c.6510026.v1
https://doi.org/10.1158/0008-5472.c.6510026.v1
Autor:
Till Acker, Boyan K. Garvalov, Amparo Acker-Palmer, Michael Kracht, Liane Jurida, Anne-Theres Henze, Angel M. Cuesta, Hui-Ke Jiao, Higinio Dopeso
Supplementary Figure S1. Epithelial-mesenchymal transition and PHD3 silencing | Supplementary Figure S2. PHD3 silencing promotes EMT through upregulation of TGFα. | Supplementary Figure S3. EGFR signaling and TGFα mediate the effects of PHD3 silenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb37c24a61b09f001e83549bdcccfaf
https://doi.org/10.1158/0008-5472.22418075.v1
https://doi.org/10.1158/0008-5472.22418075.v1
Autor:
Virginia Albiñana, Eunate Gallardo-Vara, Juan Casado-Vela, Lucía Recio-Poveda, Luisa María Botella, Angel M Cuesta
Publikováno v:
Journal of clinical medicine. 11(15)
18 p.-4 fig.-1 tab.
Research on cancer therapies focuses on processes such as angiogenesis, cell signaling, stemness, metastasis, and drug resistance and inflammation, all of which are influenced by the cellular and molecular microenvironment of
Research on cancer therapies focuses on processes such as angiogenesis, cell signaling, stemness, metastasis, and drug resistance and inflammation, all of which are influenced by the cellular and molecular microenvironment of
Autor:
Suriel, Errasti Díaz, Mercedes, Peñalva, Lucía, Recio-Poveda, Susana, Vilches, Juan, Casado-Vela, Julián, Pérez Pérez, Luisa María, Botella, Virginia, Albiñana, Angel M, Cuesta
Publikováno v:
Journal of clinical medicine. 11(11)
Hereditary Hemorrhagic Telangiectasia (HHT) is a rare disorder of vascular development. Common manifestations include epistaxis, telangiectasias and arteriovenous malformations in multiple organs. Different deletions or nonsense mutations have been d