Transgenic Overexpression of Myocilin Leads to Variable Ocular Anterior Segment and Retinal Alterations Associated with Extracellular Matrix Abnormalities in Adult Zebrafish

Autor: Raquel Atienzar-Aroca, Jesús-José Ferre-Fernández, Angel Tevar, Juan-Manuel Bonet-Fernández, María-José Cabañero, María-José Ruiz-Pastor, Nicolás Cuenca, José-Daniel Aroca-Aguilar, Julio Escribano

Publikováno v: RUA. Repositorio Institucional de la Universidad de Alicante
Universidad de Alicante (UA)
International Journal of Molecular Sciences; Volume 23; Issue 17; Pages: 9989

Myocilin is an enigmatic glaucoma-associated glycoprotein whose biological role remains incompletely understood. To gain novel insight into its normal function, we used transposon-mediated transgenesis to generate the first zebrafish line stably over

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e48480f4c754aeac4baf671eeb6af0
https://doi.org/10.3390/ijms23179989