Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Angel R. Garcia"'
Autor:
Lecia V. Sequist, Jeffrey A. Engelman, Andrew R. Allen, Alice T. Shaw, A. John Iafrate, Dora Dias-Santagata, Richard H. DiCecca, Melissa K. Parks, Hillary E. Mulvey, Angel R. Garcia, Mitch Raponi, Alona Muzikansky, Subba Digumarthy, Anuj Kalsy, Elizabeth L. Lockerman, Aaron N. Hata, Linnea Fulton, Mari Mino-Kenudson, Joel W. Neal, Heather A. Wakelee, Chris A. Karlovich, Matthew J. Niederst, Zofia Piotrowska
Supplementary Figure S1. CONSORT diagram. Supplementary Figure S2. Histologic analysis of the pre-rociletinib biopsy from patient 12 (H&E 400x, left panel) demonstrates characteristic adenocarcinoma with an open chromatin pattern, ample cytoplasm and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::437ca3efda6e4b1a14798fe61a036ad6
https://doi.org/10.1158/2159-8290.22530498.v1
https://doi.org/10.1158/2159-8290.22530498.v1
Autor:
Lecia V. Sequist, Jeffrey A. Engelman, Andrew R. Allen, Alice T. Shaw, A. John Iafrate, Dora Dias-Santagata, Richard H. DiCecca, Melissa K. Parks, Hillary E. Mulvey, Angel R. Garcia, Mitch Raponi, Alona Muzikansky, Subba Digumarthy, Anuj Kalsy, Elizabeth L. Lockerman, Aaron N. Hata, Linnea Fulton, Mari Mino-Kenudson, Joel W. Neal, Heather A. Wakelee, Chris A. Karlovich, Matthew J. Niederst, Zofia Piotrowska
Supplementary Figure Legends. Supplementary Table S1. Patient characteristics. Supplementary Table S2. Tissue genotyping analyses. Supplementary Table S3. Allelic Fraction of T790M and maximum reduction in tumor volume in response to rociletinib.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03fcd94a89f7fb896d66c6fc6bab2516
https://doi.org/10.1158/2159-8290.22530501
https://doi.org/10.1158/2159-8290.22530501
Autor:
Jeffrey A. Engelman, Lecia V. Sequist, Zofia Piotrowska, Angel R. Garcia, Elizabeth L. Lockerman, Hillary E. Mulvey, Haichuan Hu, Matthew J. Niederst
Supplementary Figure 1 Legend. Describing the qPCR assay and variant allele frequency data that are included in the figure.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e18167c22ba9c0611b588fce9c6740d
https://doi.org/10.1158/1078-0432.22457907
https://doi.org/10.1158/1078-0432.22457907
Autor:
Jeffrey A. Engelman, Lecia V. Sequist, Zofia Piotrowska, Angel R. Garcia, Elizabeth L. Lockerman, Hillary E. Mulvey, Haichuan Hu, Matthew J. Niederst
Purpose: A secondary EGFR mutation, T790M, is the most common resistance mechanism in EGFR-mutant adenocarcinomas that have progressed on erlotinib. Third-generation EGFR inhibitors capable of inhibiting mutant EGFR with T790M produce responses in ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59e3f5cd6fe326d292cde875d4764bd7
https://doi.org/10.1158/1078-0432.c.6523746.v1
https://doi.org/10.1158/1078-0432.c.6523746.v1
Autor:
Jeffrey A. Engelman, Lecia V. Sequist, Zofia Piotrowska, Angel R. Garcia, Elizabeth L. Lockerman, Hillary E. Mulvey, Haichuan Hu, Matthew J. Niederst
Supplementary Figure 1. EGFR amplification status and variant allele frequencies of T790M and C797S mutations for MGH121 parental and MGH121 resistant #1 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d730bf07d9b78031685d846a53f6defb
https://doi.org/10.1158/1078-0432.22457904.v1
https://doi.org/10.1158/1078-0432.22457904.v1
Identification of miRNAs progressively deregulated in the biological model of gastric carcinogenesis
Autor:
Sergio Ayala-Diaz, Joaquin Manzo-Merino, Rosario Morales-Espinosa, Mauricio Flores-Fortis, Roberto Lopez-Santacruz, Jorge Arturo Perales-Oliva, Angel R. Garcia-Navarro, Leonardo S. Lino-Silva, Gabriela Delgado, Amairani Aguilar-Ruiz, David Garcia-Vasquez, Luis F. Oñate, Roberto Herrera-Goepfert, Elena Arechaga-Ocampo
Gastric adenocarcinoma is the result of the progression of preneoplastic lesions in gastric mucosa. Helicobacter pylori (H. pylori) infection is the main environmental risk factor linked to the multistep progression from precancerous conditions to ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::223b36c2d5e813c3881f9c216f55f719
https://doi.org/10.21203/rs.3.rs-1991665/v1
https://doi.org/10.21203/rs.3.rs-1991665/v1
Autor:
Jungoh Ham, Anthony C. Faber, Aaron N. Hata, Maria Gomez-Caraballo, Haichuan Hu, Elizabeth L. Lockerman, Brad Windle, Shawn Gillepsie, Daniel A. R. Heisey, Sinem Esra Sahingur, Mark A. Hicks, Kyung-A Song, Shirley M. Taylor, Hillary E. Mulvey, Timothy L. Lochmann, Hiromichi Ebi, Lecia V. Sequist, Konstantinos V. Floros, Mark T. Hughes, Hidenori Kitai, Hannah L. Archibald, Angel R. Garcia, Yotam Drier, Mikhail G. Dozmorov, Tara J. Nulton, Neha U. Patel, Matthew J. Niederst, Zofia Piotrowska, Bradley E. Bernstein, Jeffrey A. Engelman
Publikováno v:
Clinical Cancer Research. 24:197-208
Purpose: Epithelial-to-mesenchymal transition (EMT) confers resistance to a number of targeted therapies and chemotherapies. However, it has been unclear why EMT promotes resistance, thereby impairing progress to overcome it. Experimental Design: We
Autor:
M. Mariano, Sara Póvoa, I. Domingues, M.R. Pires, Sofia Broco, C. Costa, G. Sousa, Angel R. Garcia, I. Ferreira Gomes, J.C. Monteiro, Isabel Pazos, Teresa Carvalho, C. Caramujo, P. Madeira, T. Fraga, F.R. Salgueiro, A.C. Caetano, António Pêgo
Publikováno v:
Annals of Oncology. 32:S1193
Autor:
C. Caramujo, M.J.P. de Sousa, J. Correia Magalhães, R. Basto, Isonda Pires, Angel R. Garcia, Azenha Cardoso, Magaly Gemio Teixeira, I. Zorrinho, G. Sousa, Leila Khouri, A.P. Leite, Francisco Branquinho, Conceição Bento
Publikováno v:
Annals of Oncology. 32:S817
Autor:
G. Sousa, R. Félix Soares, Angel R. Garcia, Maria Manuela Peixoto, J. Cunha Carvalho, Mariana Nabais, I. Domingues, T. Cunha Pereira, E. Jesus, MT Amaral, Rosimeri Aquino da Silva, Evelyn Thais de Almeida Rodrigues, Filipa Pontes, Inês Brandão Rêgo, A.R. Monteiro, Filipe Macedo, Ó. Vilão, A. Chaves
Publikováno v:
Annals of Oncology. 31:S935