Zobrazeno 1 - 10
of 326
pro vyhledávání: '"Angel R de Lera"'
Autor:
Hendrik N. J. Kuijer, Jian You Wang, Salim Bougouffa, Michael Abrouk, Muhammad Jamil, Roberto Incitti, Intikhab Alam, Aparna Balakrishna, Derry Alvarez, Cristina Votta, Guan-Ting Erica Chen, Claudio Martínez, Andrea Zuccolo, Lamis Berqdar, Salim Sioud, Valentina Fiorilli, Angel R. de Lera, Luisa Lanfranco, Takashi Gojobori, Rod A. Wing, Simon G. Krattinger, Xin Gao, Salim Al-Babili
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract The yield of pearl millet, a resilient cereal crop crucial for African food security, is severely impacted by the root parasitic weed Striga hermonthica, which requires host-released hormones, called strigolactones (SLs), for seed germinatio
Externí odkaz:
https://doaj.org/article/112bab48414a49b8a3ae35f737b8a5ed
Autor:
Ralph Rühl, Agnieszka Krzyżosiak, Anna Niewiadomska-Cimicka, Natacha Rochel, Lajos Szeles, Belén Vaz, Marta Wietrzych-Schindler, Susana Álvarez, Monika Szklenar, Laszlo Nagy, Angel R de Lera, Wojciech Krężel
Publikováno v:
PLoS Genetics, Vol 11, Iss 6, p e1005213 (2015)
The retinoid X receptors (RXRs) are ligand-activated transcription factors which heterodimerize with a number of nuclear hormone receptors, thereby controlling a variety of (patho)-physiological processes. Although synthetic RXR ligands are developed
Externí odkaz:
https://doaj.org/article/a8a62018524c4643af5c0e9dd6f976d2
Autor:
Stéphanie Bertrand, Daniel Aldea, Silvan Oulion, Lucie Subirana, Angel R de Lera, Ildiko Somorjai, Hector Escriva
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0136587 (2015)
During vertebrate development, the paraxial mesoderm becomes segmented, forming somites that will give rise to dermis, axial skeleton and skeletal muscles. Although recently challenged, the "clock and wavefront" model for somitogenesis explains how i
Externí odkaz:
https://doaj.org/article/a53ea5d8492c408b8546e43a096478c2
Autor:
Janine Gericke, Jan Ittensohn, Johanna Mihály, Susana Alvarez, Rosana Alvarez, Dániel Töröcsik, Angel R de Lera, Ralph Rühl
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62643 (2013)
Endogenous retinoids like all-trans retinoic acid (ATRA) play important roles in skin homeostasis and skin-based immune responses. Moreover, retinoid signaling was found to be dysregulated in various skin diseases. The present study used topical appl
Externí odkaz:
https://doaj.org/article/c89d2a781f58478d85c8e8fb22ed4590
Autor:
Rosana Simón-Vázquez, Marta Domínguez, Víctor A Lórenz-Fonfría, Susana Alvarez, José-Luís Bourdelande, Angel R de Lera, Esteve Padrós, Alex Perálvarez-Marín
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42447 (2012)
Bacteriorhodopsin has a polar cluster of amino acids surrounding the retinal molecule, which is responsible for light harvesting to fuel proton pumping. From our previous studies, we have shown that threonine 90 is the pivotal amino acid in this pola
Externí odkaz:
https://doaj.org/article/8dbfd59be4ea49ff9d2753dd0fd882cf
Publikováno v:
Nutrition & Metabolism, Vol 20, Iss 1, Pp 1-19 (2023)
Abstract In the last century, vitamin A was identified that included the nutritional relevant vitamin A1 / provitamin A1, as well as the vitamin A2 pathway concept. Globally, nutritional guidelines have focused on vitamin A1 with simplified recommend
Externí odkaz:
https://doaj.org/article/56467cd4a82a4f4a9a015f6f19055197
Publikováno v:
Molecules, Vol 27, Iss 21, p 7585 (2022)
Within the 2,5-dioxopiperazine-containing natural products generated by “head-to-tail” cyclization of peptides, those derived from tryptophan allow further structural diversification due to the rich chemical reactivity of the indole heterocycle,
Externí odkaz:
https://doaj.org/article/f87e2256b5b541708d18a39d246dd0f9
Autor:
Torsten Bohn, Angel R. de Lera, Jean-Francois Landrier, Harald Carlsen, Daniel Merk, Tilman Todt, Jenny Renaut, Ralph Rühl
Publikováno v:
Food & Function. 14:621-638
Research strategy for carotenoids starting with causal data from epidemiological / supplementation studies via lab experiments, multi-omics analyses and final validation. Studies should preferably be done by a consortium of multiple expert groups.
Publikováno v:
Nutrition Research Reviews. :1-14
Many epidemiological studies have emphasised the relation between carotenoid dietary intake and their circulating concentrations and beneficial health effects, such as lower risk of cardiometabolic diseases and cancer. However, there is dispute as to
Publikováno v:
Journal of Natural Products. 85:2302-2311
Financiado para publicación en acceso aberto: Universidade de Vigo/CISUG The stereoselective synthesis of C40-all-trans-carotenoids with the formal hexahydrobenzofuran skeletons aurochrome, auroxanthin, and equinenone-5′,8′-epoxide is reported.