Fatty acid synthase (FASN) is a tumor-cell-intrinsic metabolic checkpoint restricting T-cell immunity

Autor: Elisabet Cuyàs, Stefano Pedarra, Sara Verdura, Miguel Angel Pardo, Roderic Espin Garcia, Eila Serrano-Hervás, Àngela Llop-Hernández, Eduard Teixidor, Joaquim Bosch-Barrera, Eugeni López-Bonet, Begoña Martin-Castillo, Ruth Lupu, Miguel Angel Pujana, Josep Sardanyès, Tomás Alarcón, Javier A. Menendez

Publikováno v: Cell Death Discovery, Vol 10, Iss 1, Pp 1-17 (2024)

Abstract Fatty acid synthase (FASN)-catalyzed endogenous lipogenesis is a hallmark of cancer metabolism. However, whether FASN is an intrinsic mechanism of tumor cell defense against T cell immunity remains unexplored. To test this hypothesis, here w

Externí odkaz: https://doaj.org/article/cf58d85bd0c34429bd80f33b1267b08a

Corrosión galvánica de aleaciones de magnesio AM50 y AZ91D modificadas con tierras raras en contacto con acero y aleaciones de aluminio

Autor: Marta Mohedano, Raúl Arrabal, Angel Pardo, Karín Paucar, M. Concepción Merino, Endzhe Matykina, Beatriz Mingo, Gerardo Garcés

Publikováno v: Revista de Metalurgia, Vol 50, Iss 1, Pp e002-e002 (2014)

Se emplearon medidas electroquímicas y gravimétricas para examinar el efecto de la adición de neodimio y gadolinio en el comportamiento a la corrosión galvánica de las aleaciones AM50 y AZ91D en contacto con acero al carbono A 570 Gr 36 y aleaci

Externí odkaz: https://doaj.org/article/1a8cd1c0592c414ca1931d581ed0186c

Biological basis of extensive pleiotropy between blood traits and cancer risk

Autor: Miguel Angel Pardo-Cea, Xavier Farré, Anna Esteve, Joanna Palade, Roderic Espín, Francesca Mateo, Eric Alsop, Marc Alorda, Natalia Blay, Alexandra Baiges, Arzoo Shabbir, Francesc Comellas, Antonio Gómez, Montserrat Arnan, Alex Teulé, Monica Salinas, Laura Berrocal, Joan Brunet, Paula Rofes, Conxi Lázaro, Miquel Conesa, Juan Jose Rojas, Lars Velten, Wojciech Fendler, Urszula Smyczynska, Dipanjan Chowdhury, Yong Zeng, Housheng Hansen He, Rong Li, Kendall Van Keuren-Jensen, Rafael de Cid, Miquel Angel Pujana

Publikováno v: Genome Medicine, Vol 16, Iss 1, Pp 1-22 (2024)

Abstract Background The immune system has a central role in preventing carcinogenesis. Alteration of systemic immune cell levels may increase cancer risk. However, the extent to which common genetic variation influences blood traits and cancer risk r

Externí odkaz: https://doaj.org/article/5f8c5c339bf345519940b8098cf83a6d

Dynamic localization of the Na+-HCO3− co-transporter NBCn1 to the plasma membrane, centrosomes, spindle and primary cilia

Autor: Marc Severin, Emma Lind Pedersen, Magnus Thane Borre, Ida Axholm, Frederik Bendix Christiansen, Muthulakshmi Ponniah, Dominika Czaplinska, Tanja Larsen, Luis Angel Pardo, Stine Falsig Pedersen

Publikováno v: Journal of Cell Science. 136

Finely tuned regulation of transport protein localization is vital for epithelial function. The Na+-HCO3− co-transporter NBCn1 (also known as SLC4A7) is a key contributor to epithelial pH homeostasis, yet the regulation of its subcellular localizat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2e8c512fce9ef322198c40e68889b7e6
https://doi.org/10.1242/jcs.260687

A new look at the meeting clustering effect

Autor: Angel Pardo, Eddie Santandreu

Publikováno v: Pardo Tornero, Ángel Santandreu, Eddie 2023 A new look at the meeting clustering effect. Review of Behavioral Finance, 15, 2, 162-175 pp.
Pardo Tornero, Ángel Santandreu, Eddie 2021 A new look at the meeting clustering effect Review of Behavioral Finance
RODERIC. Repositorio Institucional de la Universitat de Valéncia
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PurposeThe study aims to test the existence of a meeting clustering effect in the Spanish Stock Exchange (SSE).Design/methodology/approachThis paper studies the relationship between the clustering of annual general meetings and stock returns in the S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb11ec63063eb28dc15b3f77089490a4
https://hdl.handle.net/10550/82896