Zobrazeno 1 - 10
of 205
pro vyhledávání: '"Angel M. Carcaboso"'
Autor:
Maria Wiese, Bente Pohlmeier, Klaudia Kubiak, Fatma E. El-Khouly, Maren Sitte, Angel M. Carcaboso, Joshua N. Baugh, Thomas Perwein, Gunther Nussbaumer, Michael Karremann, Gerrit H. Gielen, Gabriela Salinas, Christof M. Kramm
Publikováno v:
Journal of Traditional and Complementary Medicine, Vol 14, Iss 1, Pp 101-108 (2024)
Background and aim: Pediatric high-grade gliomas (pedHGG) comprise a very poor prognosis. Thus, parents of affected children are increasingly resorting to complementary and alternative medicine (CAM), among those Boswellia extracts. However, nothing
Externí odkaz:
https://doaj.org/article/7382fc51cc334184815e639748ac5cbb
Autor:
Nadia Mensali, Hakan Köksal, Sandy Joaquina, Patrik Wernhoff, Nicholas P. Casey, Paola Romecin, Carla Panisello, René Rodriguez, Lene Vimeux, Asta Juzeniene, Marit R. Myhre, Anne Fåne, Carolina Castilla Ramírez, Solrun Melkorka Maggadottir, Adil Doganay Duru, Anna-Maria Georgoudaki, Iwona Grad, Andrés Daniel Maturana, Gustav Gaudernack, Gunnar Kvalheim, Angel M. Carcaboso, Enrique de Alava, Emmanuel Donnadieu, Øyvind S. Bruland, Pablo Menendez, Else Marit Inderberg, Sébastien Wälchli
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Osteosarcoma (OS) remains a dismal malignancy in children and young adults, with poor outcome for metastatic and recurrent disease. Immunotherapies in OS are not as promising as in some other cancer types due to intra-tumor heterogeneity and
Externí odkaz:
https://doaj.org/article/aeb35d7698f54300a9d32846913690b0
Autor:
Cécile Thirant, Agathe Peltier, Simon Durand, Amira Kramdi, Caroline Louis-Brennetot, Cécile Pierre-Eugène, Margot Gautier, Ana Costa, Amandine Grelier, Sakina Zaïdi, Nadège Gruel, Irène Jimenez, Eve Lapouble, Gaëlle Pierron, Déborah Sitbon, Hervé J. Brisse, Arnaud Gauthier, Paul Fréneaux, Sandrine Grossetête, Laura G. Baudrin, Virginie Raynal, Sylvain Baulande, Angela Bellini, Jaydutt Bhalshankar, Angel M. Carcaboso, Birgit Geoerger, Hermann Rohrer, Didier Surdez, Valentina Boeva, Gudrun Schleiermacher, Olivier Delattre, Isabelle Janoueix-Lerosey
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Noradrenergic and mesenchymal identities have been characterized in neuroblastoma cell lines according to their epigenetic landscapes and core regulatory circuitries. However, their relationship and relative contribution in patient tumors re
Externí odkaz:
https://doaj.org/article/04ed19984e944c97b2d0494d3dadfd31
Autor:
Laura Garcia-Gerique, Marta García, Alícia Garrido-Garcia, Soledad Gómez-González, Montserrat Torrebadell, Estela Prada, Guillem Pascual-Pasto, Oscar Muñoz, Sara Perez-Jaume, Isadora Lemos, Noelia Salvador, Monica Vila-Ubach, Ana Doncel-Requena, Mariona Suñol, Angel M. Carcaboso, Jaume Mora, Cinzia Lavarino
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-17 (2022)
Abstract Background The bone marrow (BM) is the most common site of dissemination in patients with aggressive, metastatic neuroblastoma (NB). However, the molecular mechanisms underlying the aggressive behavior of NB cells in the BM niche are still g
Externí odkaz:
https://doaj.org/article/e865fdd653454824bece7e485560729a
Autor:
Lucia Lisa Petrilli, Claudia Fuoco, Alessandro Palma, Luca Pasquini, Giulia Pericoli, Yura Grabovska, Alan Mackay, Sabrina Rossi, Angel M. Carcaboso, Andrea Carai, Angela Mastronuzzi, Chris Jones, Gianni Cesareni, Franco Locatelli, Maria Vinci
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Paediatric-type diffuse high-grade gliomas (PDHGG) are aggressive tumors affecting children and young adults, with no effective treatment. These highly heterogeneous malignancies arise in different sites of the Central Nervous System (CNS), carrying
Externí odkaz:
https://doaj.org/article/94b54df944b44522a711132ecb3fea4b
Autor:
Prasidda Khadka, Zachary J. Reitman, Sophie Lu, Graham Buchan, Gabrielle Gionet, Frank Dubois, Diana M. Carvalho, Juliann Shih, Shu Zhang, Noah F. Greenwald, Travis Zack, Ofer Shapira, Kristine Pelton, Rachel Hartley, Heather Bear, Yohanna Georgis, Spandana Jarmale, Randy Melanson, Kevin Bonanno, Kathleen Schoolcraft, Peter G. Miller, Alexandra L. Condurat, Elizabeth M. Gonzalez, Kenin Qian, Eric Morin, Jaldeep Langhnoja, Leslie E. Lupien, Veronica Rendo, Jeromy Digiacomo, Dayle Wang, Kevin Zhou, Rushil Kumbhani, Maria E. Guerra Garcia, Claire E. Sinai, Sarah Becker, Rachel Schneider, Jayne Vogelzang, Karsten Krug, Amy Goodale, Tanaz Abid, Zohra Kalani, Federica Piccioni, Rameen Beroukhim, Nicole S. Persky, David E. Root, Angel M. Carcaboso, Benjamin L. Ebert, Christine Fuller, Ozgun Babur, Mark W. Kieran, Chris Jones, Hasmik Keshishian, Keith L. Ligon, Steven A. Carr, Timothy N. Phoenix, Pratiti Bandopadhayay
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Abstract The role of PPM1D mutations in de novo gliomagenesis has not been systematically explored. Here we analyze whole genome sequences of 170 pediatric high-grade gliomas and find that truncating mutations in PPM1D that increase the stability of
Externí odkaz:
https://doaj.org/article/05d88dcae9c94b0ba00bbf84c4d8c770
Autor:
Jing Liu, Daniela Ottaviani, Meriem Sefta, Céline Desbrousses, Elodie Chapeaublanc, Rosario Aschero, Nanor Sirab, Fabiana Lubieniecki, Gabriela Lamas, Laurie Tonon, Catherine Dehainault, Clément Hua, Paul Fréneaux, Sacha Reichman, Narjesse Karboul, Anne Biton, Liliana Mirabal-Ortega, Magalie Larcher, Céline Brulard, Sandrine Arrufat, André Nicolas, Nabila Elarouci, Tatiana Popova, Fariba Némati, Didier Decaudin, David Gentien, Sylvain Baulande, Odette Mariani, Florent Dufour, Sylvain Guibert, Céline Vallot, Livia Lumbroso-Le Rouic, Alexandre Matet, Laurence Desjardins, Guillem Pascual-Pasto, Mariona Suñol, Jaume Catala-Mora, Genoveva Correa Llano, Jérôme Couturier, Emmanuel Barillot, Paula Schaiquevich, Marion Gauthier-Villars, Dominique Stoppa-Lyonnet, Lisa Golmard, Claude Houdayer, Hervé Brisse, Isabelle Bernard-Pierrot, Eric Letouzé, Alain Viari, Simon Saule, Xavier Sastre-Garau, François Doz, Angel M. Carcaboso, Nathalie Cassoux, Celio Pouponnot, Olivier Goureau, Guillermo Chantada, Aurélien de Reyniès, Isabelle Aerts, François Radvanyi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Retinoblastoma is the most frequent intraocular paediatric malignancy whose molecular basis remains poorly understood. Here, the authors perform multi-omic analysis and identify two subtypes; one in a cone differentiated state and one more aggressive
Externí odkaz:
https://doaj.org/article/92fda6743ce64715a5b5d4c807ca5ced
Autor:
Lincy Thomas, Nataliya Smith, Debra Saunders, Michelle Zalles, Rafal Gulej, Megan Lerner, Kar-Ming Fung, Angel M. Carcaboso, Rheal A. Towner
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-16 (2020)
Abstract Background Diffuse intrinsic pontine glioma (DIPG) is the most common brainstem cancer in childhood. This rapidly progressing brainstem glioma holds a very dismal prognosis with median survival of less than 1 year. Despite extensive research
Externí odkaz:
https://doaj.org/article/8e95358f871e4a84a4e8aee5a3337feb
Autor:
Clémence Deligne, Johan Hachani, Sophie Duban-Deweer, Samuel Meignan, Pierre Leblond, Angel M. Carcaboso, Yasuteru Sano, Fumitaka Shimizu, Takashi Kanda, Fabien Gosselet, Marie-Pierre Dehouck, Caroline Mysiorek
Publikováno v:
Fluids and Barriers of the CNS, Vol 17, Iss 1, Pp 1-15 (2020)
Abstract Background Pediatric diffuse intrinsic pontine glioma (DIPG) represents one of the most devastating and lethal brain tumors in children with a median survival of 12 months. The high mortality rate can be explained by the ineligibility of pat
Externí odkaz:
https://doaj.org/article/498ffa16ab464982bbfc8abfc1891de8
Autor:
Angela Galardi, Christina Stathopoulos, Marta Colletti, Chiara Lavarello, Ida Russo, Raffaele Cozza, Antonino Romanzo, Angel M. Carcaboso, Franco Locatelli, Andrea Petretto, Francis L. Munier, Angela Di Giannatale
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13458 (2022)
Aqueous humor (AH) can be easily and safely used to evaluate disease-specific biomarkers in ocular disease. The aim of this study was to identify specific proteins biomarkers in the AH of retinoblastoma (RB) patients at various stages of the disease.
Externí odkaz:
https://doaj.org/article/f68649d7836e44529a14ed8789213fdb