Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Angel M Aponte"'
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0255860 (2021)
The molecular mechanisms underlying morphological diversity in retinal cell types are poorly understood. We have previously reported that several members of the Copine family of Ca-dependent membrane adaptors are expressed in Retinal Ganglion Cells a
Externí odkaz:
https://doaj.org/article/6d48dafdd6204749bbc7f50fc0fe0f4d
Autor:
Passley Hargrove-Grimes, Anupam K Mondal, Jessica Gumerson, Jacob Nellissery, Angel M Aponte, Linn Gieser, Haohua Qian, Robert N Fariss, Juan S Bonifacino, Tiansen Li, Anand Swaroop
Publikováno v:
PLoS Genetics, Vol 16, Iss 12, p e1009259 (2020)
Rab-GTPases and associated effectors mediate cargo transport through the endomembrane system of eukaryotic cells, regulating key processes such as membrane turnover, signal transduction, protein recycling and degradation. Using developmental transcri
Externí odkaz:
https://doaj.org/article/8c3768f9127e45a389aa474eafd00c5f
Autor:
Alexander V. Sorokin, Christin G. Hong, Angel M. Aponte, Elizabeth M. Florida, Jingrong Tang, Nidhi Patel, Irina N. Baranova, Haiou Li, Philip M. Parel, Vicky Chen, Sierra R. Wilson, Emily L. Ongstad, Anna Collén, Martin P. Playford, Thomas L. Eggerman, Marcus Y. Chen, Kazuhiko Kotani, Alexander V. Bocharov, Alan T. Remaley
Publikováno v:
JCI Insight, Vol 8, Iss 20 (2023)
BACKGROUND. Oxidized apolipoprotein B (oxLDL) and oxidized ApoA-I (oxHDL) are proatherogenic. Their prognostic value for assessing high-risk plaques by coronary computed tomography angiography (CCTA) is missing.METHODS. In a prospective, observationa
Externí odkaz:
https://doaj.org/article/07ac5b93ee004406b7e818020909e4a4
Autor:
Masaki Sato, Edward B. Neufeld, Martin P. Playford, Yu Lei, Alexander V. Sorokin, Angel M. Aponte, Lita A. Freeman, Scott M. Gordon, Amit K. Dey, Kianoush Jeiran, Masato Hamasaki, Maureen L. Sampson, Robert D. Shamburek, Jingrong Tang, Marcus Y. Chen, Kazuhiko Kotani, Josephine L.C. Anderson, Robin P.F. Dullaart, Nehal N. Mehta, Uwe J.F. Tietge, Alan T. Remaley
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 18 (2023)
BACKGROUND Cellular cholesterol efflux capacity (CEC) is a better predictor of cardiovascular disease (CVD) events than HDL-cholesterol (HDL-C) but is not suitable as a routine clinical assay.METHODS We developed an HDL-specific phospholipid efflux (
Externí odkaz:
https://doaj.org/article/39566e9a46204437a84f2a721f256ea3
Autor:
Zhi-Hong Yang, Marcelo Amar, Maureen Sampson, Amber B. Courville, Alexander V. Sorokin, Scott M. Gordon, Angel M. Aponte, Michael Stagliano, Martin P. Playford, Yi-Ping Fu, Shanna Yang, Nehal N. Mehta, Alan T. Remaley
Publikováno v:
Nutrients, Vol 12, Iss 3, p 749 (2020)
Background: Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have both shared and different cardiovascular effects, and commonly used fish oil supplements have considerably varied EPA/DHA ratios. Aims: We compared the effects of fish oil su
Externí odkaz:
https://doaj.org/article/ca957a5fbb914bc59420b254a8560c61
Autor:
Kianoush Jeiran, Scott M. Gordon, Denis O. Sviridov, Angel M. Aponte, Amanda Haymond, Grzegorz Piszczek, Diego Lucero, Edward B. Neufeld, Iosif I. Vaisman, Lance Liotta, Ancha Baranova, Alan T. Remaley
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11480
ApoB-100 is a member of a large lipid transfer protein superfamily and is one of the main apolipoproteins found on low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL) particles. Despite its clinical significance for the development
Autor:
Christie K. Campla, Ulisse Bocchero, Ryan Strickland, Jacob Nellissery, Jayshree Advani, Irina Ignatova, Dhiraj Srivastava, Angel M. Aponte, Yuchen Wang, Jessica Gumerson, Kirill Martemyanov, Nikolai O. Artemyev, Johan Pahlberg, Anand Swaroop
Publikováno v:
eNeuro. 9(5)
Trafficking of transducin (Gαt) in rod photoreceptors is critical for adaptive and modulatory responses of the retina to varying light intensities. In addition to fine-tuning phototransduction gain in rod outer segments (OSs), light-induced transloc
Autor:
Yingfan Zhang, T. Bradley Willingham, Laura Reyes, Chengyu Liu, Danielle Springer, Audrey Noguchi, Angel M. Aponte, Jeeva Munasinghe, Raul Covian, Brian Glancy
Depletion of transmembrane protein 65 (TMEM65) in a patient with a homozygous point mutation in the TMEM65 gene splice site was reported to result in mitochondrial dysfunction and severe encephalomyopathy(1), indicating the clinical importance of TME
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d00932474052bdc5591e0a48e335f116
https://doi.org/10.1101/2022.08.02.502535
https://doi.org/10.1101/2022.08.02.502535
Autor:
Angel M. Aponte, Xiaoyan Shen, Rong Fong Shen, Martha Vaughan, Eric M. Billings, Joel Moss, Chun Chun Li
Publikováno v:
Proceedings of the National Academy of Sciences. 109:14464-14469
Brefeldin A-inhibited guanine nucleotide-exchange protein (BIG)2 activates ADP-ribosylation factors, ∼20-kDa GTPase proteins critical for continuity of intracellular vesicular trafficking by accelerating the replacement of ADP-ribosylation factor-b
Autor:
Atsushi Kuno, Charles Steenbergen, Tetsuji Miura, Angel M Aponte, Elizabeth Murphy, Toshiyuki Yano, Marcella Ferlito
Rationale: There is tight coupling between Akt activation and suppression of cell death. Full Akt activation requires mammalian target of rapamycin complex 2 (mTORC2), but the regulation of mTORC2 is unclear. Objective: To gain new insights into mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59baab4232f7f44545cee2254b0c1096
https://europepmc.org/articles/PMC4006628/
https://europepmc.org/articles/PMC4006628/