Preparation of pH-sensitive nanogels bioconjugated with shark antibodies (VNAR) for targeted drug delivery with potential applications in colon cancer therapies.

Autor: Lizbeth A Manzanares-Guevara, Jahaziel Gasperin-Bulbarela, Olivia Cabanillas-Bernal, Monserrat Renteria-Maciel, Angel Licea-Claverie, Eugenio R Méndez, Alexei F Licea-Navarro

Publikováno v: PLoS ONE, Vol 19, Iss 1, p e0294874 (2024)

Cancer is the second leading cause of death worldwide. To combat this disease, novel and specialized therapeutic systems are urgently needed. This is the first study to explore a system that combines shark variable domain (Fv) of new antigen receptor

Externí odkaz: https://doaj.org/article/9b5e30aa781545fd9e2a91939f0f7374

Poly(N-vinylcaprolactam)–Gold Nanorods–5 Fluorouracil Hydrogels: In the Quest of a Material for Topical Therapies against Melanoma Skin Cancer

Autor: Mirian A. González-Ayón, Alondra Rochin-Galaviz, Arturo Zizumbo-López, Angel Licea-Claverie

Publikováno v: Pharmaceutics, Vol 15, Iss 4, p 1097 (2023)

Chemically crosslinked hydrogels based on poly(N-vinylcaprolactam) (PNVCL) were synthetized by a photoinitiated chemical method. A galactose-based monomer, 2-lactobionamidoethyl methacrylate (LAMA), and N-vinylpyrrolidone (NVP) were added with the ai

Externí odkaz: https://doaj.org/article/85ce90636ff6481e87f3159a92a696b6

NVCL-Based Galacto-Functionalized and Thermosensitive Nanogels with GNRDs for Chemo/Photothermal-Therapy

Autor: Mirian A. González-Ayón, Jacob Licea-Rodriguez, Eugenio R. Méndez, Angel Licea-Claverie

Publikováno v: Pharmaceutics, Vol 14, Iss 3, p 560 (2022)

Dual-function nanogels (particle size from 98 to 224 nm) synthesized via surfactant-free emulsion polymerization (SFEP) were tested as smart carriers toward synergistic chemo- and photothermal therapy. Cisplatin (CDDP) or doxorubicin (DOX) and gold n

Externí odkaz: https://doaj.org/article/b911921f9cc8418bbfd7c137b5789e2b

Link between Morphology, Structure, and Interactions of Composite Microgels

Autor: Rodrigo Rivas-Barbosa, José Ruiz-Franco, Mayra A. Lara-Peña, Jacopo Cardellini, Angel Licea-Claverie, Fabrizio Camerin, Emanuela Zaccarelli, Marco Laurati

Publikováno v: Macromolecules, 55(5), 1834-1843
Macromolecules 55 (2022) 5
Macromolecules (Online) 55 (2022): 1834–1843. doi:10.1021/acs.macromol.1c02171
info:cnr-pdr/source/autori:Rivas-Barbosa R.; Ruiz-Franco J.; Lara-Pena M.A.; Cardellini J.; Licea-Claverie A.; Camerin F.; Zaccarelli E.; Laurati M./titolo:Link between Morphology, Structure, and Interactions of Composite Microgels/doi:10.1021%2Facs.macromol.1c02171/rivista:Macromolecules (Online)/anno:2022/pagina_da:1834/pagina_a:1843/intervallo_pagine:1834–1843/volume:55

We combine small angle scattering experiments and simulations to investigate the internal structure and interactions of composite Poly(N-isopropylacrylamide)-Poly(ethylene glycol) (PNIPAM-PEG) microgels. At low temperatures the experimentally determi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d8698c495ff070422bdd2535316b8b3
https://doi.org/10.1021/acs.macromol.1c02171

Nanomaterials

Autor: Yadira Denisse Cerda-Sumbarda, Arturo Zizumbo-Lopez, Angel Licea-Claverie

Publikováno v: Phytochemical Nanodelivery Systems as Potential Biopharmaceuticals ISBN: 9780323903905

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::66d663dd6b162931b514dc7246d5a9f6
https://doi.org/10.1016/b978-0-323-90390-5.00008-6