Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Angel L. De Blas"'
Autor:
Tzu-Ting Chiou, Philip Long, Alexandra Schumann-Gillett, Venkateswarlu Kanamarlapudi, Stefan A. Haas, Kirsten Harvey, Megan L. O’Mara, Angel L. De Blas, Vera M. Kalscheuer, Robert J. Harvey
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
The recruitment of inhibitory GABAA receptors to neuronal synapses requires a complex interplay between receptors, neuroligins, the scaffolding protein gephyrin and the GDP-GTP exchange factor collybistin (CB). Collybistin is regulated by protein-pro
Externí odkaz:
https://doaj.org/article/f9a09b1b8b95485cbec9f94068e7d8ad
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0217094 (2019)
Local neocortical circuits play critical roles in information processing, including synaptic plasticity, circuit physiology, and learning, and GABAergic inhibitory interneurons have key roles in these circuits. Moreover, specific neurological disorde
Externí odkaz:
https://doaj.org/article/61affbe84b8740a7a519626b5d14e091
Publikováno v:
Cellular and Molecular Neurobiology. 42:1585-1604
It has been shown that subunit composition is the main determinant of the synaptic or extrasynaptic localization of GABAA receptors (GABAARs). Synaptic and extrasynaptic GABAARs are involved in phasic and tonic inhibition, respectively. It has been p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b7ccd6ae5f3db5a52f52e950880741d
https://doi.org/10.1007/s10571-021-01050-1
https://doi.org/10.1007/s10571-021-01050-1
Autor:
Celia P. Miralles, Angel L. De Blas, Shanu George, Tzu-Ting Chiou, Theofilos Papadopoulos, Michael J. Taylor, John Bear, Christopher D. Fekete, Karthik Kanamalla
Publikováno v:
Journal of Neurochemistry. 157:1032-1051
Collybistin (CB) is a guanine nucleotide exchange factor (GEF) selectively localized at GABAergic and glycinergic postsynapses. Analysis of mRNA shows that several isoforms of collybistin are expressed in the brain. Some of the isoforms have a SH3 do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64b380427649baba8464a159c05623e
https://doi.org/10.1111/jnc.15270
https://doi.org/10.1111/jnc.15270
Publikováno v:
eNeuro
Collybistin (CB) is a rho guanine exchange factor found at GABAergic and glycinergic postsynapses that interacts with the inhibitory scaffold protein, gephyrin, and induces accumulation of gephyrin and GABAA receptors (GABAARs) to the postsynapse. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef172c87b163909b13c1fd137c03ec7d
http://europepmc.org/articles/PMC8281261
http://europepmc.org/articles/PMC8281261
Autor:
Angel L. De Blas, Shanu George, Tzu-Ting Chiou, John Bear, Celia P. Miralles, Christopher D. Fekete, Michael J. Taylor, Yanfang Li, Bevan Bonhomme
Publikováno v:
J Comp Neurol
It has been proposed that the combinatorial expression of γ-protocadherins (Pcdh-γs) and other clustered protocadherins (Pcdhs) provides a code of molecular identity and individuality to neurons, which plays a major role in the establishment of spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e33b4f4c4732eb78f12a6726e6024711
https://pubmed.ncbi.nlm.nih.gov/31609469
https://pubmed.ncbi.nlm.nih.gov/31609469
Publikováno v:
Cellular and Molecular Neurobiology. 42:1605-1605
The original version of this article unfortunately contained editorial errors in supplementary material.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::baa98c45a9d42996a93d3de2c987dfa3
https://doi.org/10.1007/s10571-021-01061-y
https://doi.org/10.1007/s10571-021-01061-y
Autor:
Tzu-Ting Chiou, Joseph J. LoTurco, John Bear, Angel L. De Blas, Sean Dinallo, Christopher D. Fekete, Celia P. Miralles, Christopher G. Fiondella, Roman Goz
Publikováno v:
Journal of Comparative Neurology. 525:1291-1311
Collybistin (CB) is a guanine nucleotide exchange factor selectively localized to γ-aminobutyric acid (GABA)ergic and glycinergic postsynapses. Active CB interacts with gephyrin, inducing the submembranous clustering and the postsynaptic accumulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d42c5d6568506fd8480f769b4e895842
https://doi.org/10.1002/cne.24137
https://doi.org/10.1002/cne.24137
Autor:
Tzu-Ting Chiou, Rashid Ali, Angel L. De Blas, Haiyan Xiao, Tom Maniatis, Bevan Bonhomme, Hongbing Jin, Yanfang Li, Noelia Pinal, Weisheng V. Chen, Celia P. Miralles
Publikováno v:
The Journal of Neuroscience. 32:11780-11797
We have found that the γ2 subunit of the GABAAreceptor (γ2-GABAAR) specifically interacts with protocadherin-γC5 (Pcdh-γC5) in the rat brain. The interaction occurs between the large intracellular loop of the γ2-GABAAR and the cytoplasmic domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329f4156d13a634500e9c7434d28d474
https://doi.org/10.1523/jneurosci.0969-12.2012
https://doi.org/10.1523/jneurosci.0969-12.2012
Autor:
Kirsten Harvey, Haiyan Xiao, Robert J. Harvey, Zhanyan Fu, Stefano Vicini, Hongbing Jin, Angel L. De Blas, Bevan Bonhomme, Tzu-Ting Chiou, Celia P. Miralles
Publikováno v:
Journal of Biological Chemistry. 286:22456-22468
Collybistin promotes submembrane clustering of gephyrin and is essential for the postsynaptic localization of gephyrin and γ-aminobutyric acid type A (GABA(A)) receptors at GABAergic synapses in hippocampus and amygdala. Four collybistin isoforms ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1173821e32cd7f02f6849da6139b4a5b
https://doi.org/10.1074/jbc.m111.236190
https://doi.org/10.1074/jbc.m111.236190