Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Angel L. Armesilla"'
Autor:
Suhail Ahmed, Sathishkumar Kurusamy, Ezra Leander Santhosh David, Kinza Khan, Krithika Kalyanakrishnan, Miebaka Ian-Gobo, Teja Manidhar Kola, Robert N. Wilkinson, Vinodh Kannappan, Weiguang Wang, Manuel J. Gómez, Juan Miguel Redondo, James Cotton, Angel L. Armesilla
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Angiogenesis is a multi-factorial physiological process deregulated in human diseases characterised by excessive or insufficient blood vessel formation. Emerging evidence highlights a novel role for microRNAs as regulators of angiogenesis. P
Externí odkaz:
https://doaj.org/article/6a12002216dc45d3a8a5d019f2027bbc
Autor:
Aaron M. Savage, Sathishkumar Kurusamy, Yan Chen, Zhen Jiang, Karishma Chhabria, Ryan B. MacDonald, Hyejeong R. Kim, Heather L. Wilson, Fredericus J. M. van Eeden, Angel L. Armesilla, Timothy J. A. Chico, Robert N. Wilkinson
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Calcium signalling downstream of VEGF is essential for VEGF-induced angiogenesis. Here Savage et al. show that Transmembrane Protein 33 (TMEM33) is required for angiogenesis and the endothelial calcium response to VEGF, revealing a function for TMEM3
Externí odkaz:
https://doaj.org/article/47f0ef6f17ce4a149e51a23dc2a30f3c
Autor:
Kate Butcher, Vinodh Kannappan, Rajagopal Sharada Kilari, Mark R. Morris, Christopher McConville, Angel L. Armesilla, Weiguang Wang
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background Disulfiram (DS), an antialcoholism medicine, demonstrated strong anticancer activity in the laboratory but did not show promising results in clinical trials. The anticancer activity of DS is copper dependent. The reaction of DS an
Externí odkaz:
https://doaj.org/article/9531dbdda26e40e2b22c82459915b5f7
Autor:
Ibrahim R. Khalil, Martin P. Khechara, Sathishkumar Kurusamy, Angel L. Armesilla, Abhishek Gupta, Barbara Mendrek, Tamara Khalaf, Mariastella Scandola, Maria Letizia Focarete, Marek Kowalczuk, Iza Radecka
Publikováno v:
Molecules, Vol 23, Iss 10, p 2565 (2018)
In recent years, there has been an increasing interest in oncolytic adenoviral vectors as an alternative anticancer therapy. The induction of an immune response can be considered as a major limitation of this kind of application. Significant research
Externí odkaz:
https://doaj.org/article/62fbb2ac4d2c4a90a237708261185979
Autor:
Weiguang Wang, Xiu-Wu Bian, Peng Liu, Mohammad Najlah, Mark R. Morris, Angel L. Armesilla, Rajagopal S. Kilari, Sathishkumar Kurusamy, Karim Azar, Zhipeng Wang, Ying Liu, Vinodh Kannappan
Supplementary Figure from PLGA–Nano-Encapsulated Disulfiram Inhibits Hypoxia-Induced NF-κB, Cancer Stem Cells, and Targets Glioblastoma In Vitro and In Vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c61d29b0b95ab1a2d5dd06992dd58d
https://doi.org/10.1158/1535-7163.22523343
https://doi.org/10.1158/1535-7163.22523343
Autor:
Vinodh Kannappan, Ying Liu, Zhipeng Wang, Karim Azar, Sathishkumar Kurusamy, Rajagopal S. Kilari, Angel L. Armesilla, Mark R. Morris, Mohammad Najlah, Peng Liu, Xiu-Wu Bian, Weiguang Wang
Publikováno v:
Molecular cancer therapeutics. 21(8)
Glioblastoma stem cell (GSC) is the major cause of glioblastoma multiforme (GBM) chemotherapy failure. Hypoxia is one of the determinants of GSC. NF-κB plays a pivotal link between hypoxia and cancer stem cells (CSCs). Disulfiram, an antialcoholism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74a6b5ec1dd19c8e48743e841788bd45
https://pubmed.ncbi.nlm.nih.gov/35579893
https://pubmed.ncbi.nlm.nih.gov/35579893
Autor:
Alexandra Njegic, Agnieszka Swiderska, Elizabeth J. Cartwright, Charlotte Marris, Angel L. Armesilla
Publikováno v:
Journal of Molecular and Cellular Cardiology
This is an accepted manuscript of an article published by Elsevier in Journal of Molecular and Cellular Cardiology, available online: https://doi.org/10.1016/j.yjmcc.2021.03.011 The accepted version of the publication may differ from the final publis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::677c7ed5ba9320b47f97c57e2f993634
https://pubmed.ncbi.nlm.nih.gov/33781822
https://pubmed.ncbi.nlm.nih.gov/33781822
Autor:
Ben Wrigley, Mamas A. Mamas, Alexandra Moss, Saib Khogali, Angel L. Armesilla, Nazish Khan, Shahzad Munir, Andrew Smallwood, James Cotton, Diana A. Gorog, Peter Nightingale
Publikováno v:
Thrombosis research. 196
Background Aspirin forms a cornerstone of management in patients with established cardiovascular disease (CVD). Despite proven efficacy, variability of aspirin response has long been recognised, with early studies suggesting rates of high on treatmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf68b0ef5baaada2ee3921f8fa040dbe
https://pubmed.ncbi.nlm.nih.gov/33099177
https://pubmed.ncbi.nlm.nih.gov/33099177
Autor:
Ivonne Olivares, Michael D. Jenkinson, Angel L. Armesilla, Charles Davis, Timothy Dawson, Tracy Warr, Andrew Brodbelt, Mark R. Morris, Kate Ashton
Publikováno v:
British Journal of Cancer. 119:1-49
Scottish Event Campus, Glasgow, Sunday 4 – Tuesday 6 November 2018 Attendees of the 2018 NCRI Cancer Conference will be able to contact corresponding authors through the Conference App and e-poster platform at the Conference. W: https://conference.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f29eb578d58ed7c6e76b4b1fd06e45ba
https://doi.org/10.1038/s41416-018-0299-z
https://doi.org/10.1038/s41416-018-0299-z
Autor:
James Brown, Jin Ding, Xiuwu Bian, Angel L. Armesilla, Wen Guo Jiang, Juan M. Irache, Yuhuan Tan, Christopher F McConville, Jiao Tan, Patricia Erebi Tawari, Vinodh Kannappan, Weiguang Wang, Ying Liu, Qibing Mei, Zhipeng Wang
Publikováno v:
Nanomedicine
Disulfiram (DS), an anti-alcoholism drug, shows very strong cytotoxicity in many cancer types. However its clinical application in cancer treatment is limited by the very short half-life in the bloodstream. In this study, we developed a poly lactic-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c89cb5d22728ab3ca57e798343124e
https://doi.org/10.1016/j.nano.2016.08.001
https://doi.org/10.1016/j.nano.2016.08.001