Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Angel Elizondo"'
Autor:
Andrea M. Costello, Miguel-Angel Elizondo-Riojas, Xin Li, David E. Volk, Anil K. Pillai, Hongyu Wang
Publikováno v:
Molecules, Vol 26, Iss 21, p 6525 (2021)
The application of aptamers in biomedicine is emerging as an essential technology in the field of cancer research. As small single-stranded DNA or RNA ligands with high specificity and low immunogenicity for their targets, aptamers provide many advan
Externí odkaz:
https://doaj.org/article/8ad852c2e154486eb8bd2225bd6512d1
Autor:
Hongyu Wang, Xin Li, David E. Volk, Ganesh L.-R. Lokesh, Miguel-Angel Elizondo-Riojas, Li Li, Alpa M. Nick, Anil K. Sood, Kevin P. Rosenblatt, David G. Gorenstein
Publikováno v:
BioTechniques, Vol 61, Iss 5, Pp 249-259 (2016)
High affinity aptamer-based biomarker discovery has the advantage of simultaneously discovering an aptamer affinity reagent and its target biomarker protein. Here, we demonstrate a morphology-based tissue aptamer selection method that enables us to u
Externí odkaz:
https://doaj.org/article/24d2a00ff8614c07a1e8e263ccbc4ccb
Autor:
David E. Volk, Anil K. Pillai, Hongyu Wang, Miguel-Angel Elizondo-Riojas, Andrea M Costello, Xin Li
Publikováno v:
Molecules
Volume 26
Issue 21
Molecules, Vol 26, Iss 6525, p 6525 (2021)
Volume 26
Issue 21
Molecules, Vol 26, Iss 6525, p 6525 (2021)
The application of aptamers in biomedicine is emerging as an essential technology in the field of cancer research. As small single-stranded DNA or RNA ligands with high specificity and low immunogenicity for their targets, aptamers provide many advan
Autor:
Diana Cristina Pérez-Ibave, Victor Trevino, Carlos Horacio Burciaga-Flores, Hazyadee Frecia Rodríguez-Gutiérrez, Antonio Alí Pérez-Maya, Genaro A. Ramirez-Correa, Moises Gonzalez-Escamilla, María Lourdes Garza-Rodríguez, Oscar Vidal-Gutiérrez, Miguel Angel Elizondo-Riojas
Publikováno v:
Diagnostics
Diagnostics, Vol 11, Iss 411, p 411 (2021)
Diagnostics, Vol 11, Iss 411, p 411 (2021)
Familial adenomatous polyposis (FAP) is an autosomal-dominant condition characterized by the presence of multiple colorectal adenomas, caused by germline variants in the adenomatous polyposis coli (APC) gene. More than 300 germline variants have been
Autor:
Anil K. Sood, Xin Li, Miguel Angel Elizondo-Riojas, Alpa M. Nick, David G. Gorenstein, David E. Volk, Ganesh L.R. Lokesh, Kevin P. Rosenblatt, Li Li, Hongyu Wang
Publikováno v:
BioTechniques. 61:249-259
High affinity aptamer-based biomarker discovery has the advantage of simultaneously discovering an aptamer affinity reagent and its target biomarker protein. Here, we demonstrate a morphology-based tissue aptamer selection method that enables us to u
Publikováno v:
Cancer epidemiology. 54
Prostate-specific antigen (PSA) is a serine protease produced by epithelial prostatic cells and its main function is to liquefy seminal coagulum. Currently, PSA is a biomarker for the diagnosis and screening of prostate cancer and it was the first ca
Publikováno v:
Annals of the New York Academy of Sciences. 1270:73-78
Thymosin proteins, originally isolated from fractionation of thymus tissue, represent a class of compounds that we now know are present in numerous other tissues, are unrelated to each other in a genetic sense, and appear to have different functions
Autor:
David G. Gorenstein, Cynthia W. Tuthill, Steven M. Chamow, David E. Volk, Miguel-Angel Elizondo-Riojas
Publikováno v:
Biochemical and Biophysical Research Communications. 416:356-361
800 MHz NMR structure of the 28-residue peptide thymosin alpha-1 in 40% TFE/60% water (v/v) has been determined. Restrained molecular dynamic simulations with an explicit solvent box containing 40% TFE/60% TIP3P water (v/v) were used, in order to get
Publikováno v:
Biochemistry
Next-generation sequencing results from bead-based aptamer libraries have demonstrated that traditional DNA/RNA alignment software is insufficient. This is particularly true for X-aptamers containing specialty bases (W, X, Y, Z, ...) that are identif
Publikováno v:
Molecular Therapy. 23
Aptamers are oligonucleotide or peptide molecules that bind to a specific target with high affinity and specificity. A diverse range of modifications have been reported for either enhancing aptamers’ nuclease resistance or expanding their chemical