Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Angel Diaz-Lagares"'
Autor:
Andrea G Izquierdo, Hatim Boughanem, Angel Diaz-Lagares, Isabel Arranz-Salas, Manel Esteller, Francisco J Tinahones, Felipe F Casanueva, Manuel Macias-Gonzalez, Ana B Crujeiras
Publikováno v:
Epigenetics, Vol 17, Iss 6, Pp 665-676 (2022)
Adipose tissue dysfunction, particularly the visceral (VAT) compartment, has been proposed to play a relevant role in colorectal cancer (CRC) development and progression. Epigenetic mechanisms could be involved in this association. The current study
Externí odkaz:
https://doaj.org/article/d9d58e8f0259473e9893aa2cbfa9fefd
Autor:
Eva G. Álvarez, Jonas Demeulemeester, Paula Otero, Clemency Jolly, Daniel García-Souto, Ana Pequeño-Valtierra, Jorge Zamora, Marta Tojo, Javier Temes, Adrian Baez-Ortega, Bernardo Rodriguez-Martin, Ana Oitaben, Alicia L. Bruzos, Mónica Martínez-Fernández, Kerstin Haase, Sonia Zumalave, Rosanna Abal, Jorge Rodríguez-Castro, Aitor Rodriguez-Casanova, Angel Diaz-Lagares, Yilong Li, Keiran M. Raine, Adam P. Butler, Iago Otero, Atsushi Ono, Hiroshi Aikata, Kazuaki Chayama, Masaki Ueno, Shinya Hayami, Hiroki Yamaue, Kazuhiro Maejima, Miguel G. Blanco, Xavier Forns, Carmen Rivas, Juan Ruiz-Bañobre, Sofía Pérez-del-Pulgar, Raúl Torres-Ruiz, Sandra Rodriguez-Perales, Urtzi Garaigorta, Peter J. Campbell, Hidewaki Nakagawa, Peter Van Loo, Jose M. C. Tubio
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Hepatitis B virus (HBV) infection and DNA integration is a frequent cause of hepatocellular carcinoma (HCC), but the consequences of this process are not fully understood. Here the authors use whole-genome and long-read sequencing data from HCC patie
Externí odkaz:
https://doaj.org/article/9d6ae04fdf164e1683ea18005b4462b3
Autor:
Giorgia Sonzini, Sofia Granados-Aparici, Sabina Sanegre, Angel Diaz-Lagares, Juan Diaz-Martin, Carlos de Andrea, Núria Eritja, Aida Bao-Caamano, Nicolás Costa-Fraga, David García-Ros, Carmen Salguero-Aranda, Ben Davidson, Rafael López-López, Ignacio Melero, Samuel Navarro, Santiago Ramon y Cajal, Enrique de Alava, Xavier Matias-Guiu, Rosa Noguera
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The incidence of new cancer cases is expected to increase significantly in the future, posing a worldwide problem. In this regard, precision oncology and its diagnostic tools are essential for developing personalized cancer treatments. Digital pathol
Externí odkaz:
https://doaj.org/article/1debe2f1f3eb466fb9188e4c9d95f9d3
Autor:
Sara Pischedda, Irene Rivero-Calle, Alberto Gómez-Carballa, Miriam Cebey-López, Ruth Barral-Arca, Jose Gómez-Rial, Jacobo Pardo-Seco, María-José Curras-Tuala, Sandra Viz-Lasheras, Xabier Bello, Ana B. Crujeiras, Angel Diaz-Lagares, María Teresa González-López, Federico Martinón-Torres, Antonio Salas, GENDRES consortium
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundRespiratory syncytial virus (RSV) infection has been associated with the subsequent development of recurrent wheezing and asthma, although the mechanisms involved are still unknown. We investigate the role of epigenetics in the respiratory
Externí odkaz:
https://doaj.org/article/e1e9b5c55efb4e079e171eb741e1ea6e
Autor:
Begoña Pineda, Angel Diaz-Lagares, José Alejandro Pérez-Fidalgo, Octavio Burgués, Inés González-Barrallo, Ana B. Crujeiras, Juan Sandoval, Manel Esteller, Ana Lluch, Pilar Eroles
Publikováno v:
Clinical Epigenetics, Vol 11, Iss 1, Pp 1-11 (2019)
Abstract Background Pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) in triple-negative breast cancer (TNBC) varies between 30 and 40% approximately. To provide further insight into the prediction of pCR, we evaluated the rol
Externí odkaz:
https://doaj.org/article/7f903dd11caf4c39804ae0860ef80b4b
Autor:
Aitor Rodriguez-Casanova, Nicolás Costa-Fraga, Aida Bao-Caamano, Rafael López-López, Laura Muinelo-Romay, Angel Diaz-Lagares
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Colorectal cancer (CRC) is one of the most common malignancies and is a major cause of cancer-related deaths worldwide. Thus, there is a clinical need to improve early detection of CRC and personalize therapy for patients with this disease. In the er
Externí odkaz:
https://doaj.org/article/6cccdcfe4ac344d78cd57264ea16ecdc
Autor:
Paula M. Lorenzo, Andrea G. Izquierdo, Angel Diaz-Lagares, Marcos C. Carreira, Manuel Macias-Gonzalez, Juan Sandoval, Juan Cueva, Rafael Lopez-Lopez, Felipe F. Casanueva, Ana B. Crujeiras
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
The methylation levels of ZNF577 in breast tumors has been previously identified as a possible epigenetic mark of breast cancer associated with obesity. The aim of the current study was to investigate differences in methylation levels of ZNF577 depen
Externí odkaz:
https://doaj.org/article/3b738b0dd3274e0da54c277399a3dd74
Autor:
Aitor Rodríguez-Casanova, Aida Bao-Caamano, Ramón M. Lago-Lestón, Elena Brozos-Vázquez, Nicolás Costa-Fraga, Isabel Ferreirós-Vidal, Ihab Abdulkader, Yolanda Vidal-Insua, Francisca Vázquez Rivera, Sonia Candamio Folgar, Rafael López-López, Laura Muinelo-Romay, Angel Diaz-Lagares
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 19, p 4487 (2021)
Molecular profiling of circulating cell-free DNA (cfDNA) has shown utility for the management of colorectal cancer (CRC). TruSight Tumor 170 (TST170) is a next-generation sequencing (NGS) panel that covers 170 cancer-related genes, including KRAS, wh
Externí odkaz:
https://doaj.org/article/fd2de473015f4bb59e8e3c2b963a7f9d
Autor:
Cora Palanca-Ballester, Aitor Rodriguez-Casanova, Susana Torres, Silvia Calabuig-Fariñas, Francisco Exposito, Diego Serrano, Esther Redin, Karmele Valencia, Eloisa Jantus-Lewintre, Angel Diaz-Lagares, Luis Montuenga, Juan Sandoval, Alfonso Calvo
Publikováno v:
Cancers, Vol 13, Iss 12, p 3016 (2021)
Early alterations in cancer include the deregulation of epigenetic events such as changes in DNA methylation and abnormal levels of non-coding (nc)RNAs. Although these changes can be identified in tumors, alternative sources of samples may offer adva
Externí odkaz:
https://doaj.org/article/a3346f09e04b4fcd8ef3273e6d654286
Autor:
Lidia García-Colmenero, Jéssica González, Juan Sandoval, Yolanda Guillén, Angel Diaz-Lagares, Evelyn Andrades, Arnau Iglesias, Lara Nonell, Ramon Maria Pujol, Anna Bigas, Lluís Espinosa, Fernando Gallardo
Publikováno v:
Cells, Vol 9, Iss 12, p 2692 (2020)
Increasing evidence supports a potential role for STAT3 as a tumor driver in cutaneous T-cell lymphomas (CTCL). The mechanisms leading to STAT3 activation are not fully understood; however, we recently found that miR-124, a known STAT3 regulator, is
Externí odkaz:
https://doaj.org/article/d6329ff60193474e860ed2d3e0c2f144