Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Angel Díaz-Lagares"'
Autor:
Rocío Rosas-Alonso, Julian Colmenarejo-Fernández, Olga Pernía, Miranda Burdiel, Carlos Rodríguez-Antolín, Itsaso Losantos-García, Tania Rubio, Rocío Moreno-Velasco, Isabel Esteban-Rodríguez, Virginia Martínez-Marín, Paloma Yubero, Nicolas Costa-Fraga, Angel Díaz-Lagares, Rafael López-López, Eva Díaz-Martin, Juan F. García, Catalina Vivancos Sánchez, Maria Luisa Gandía-González, Gema Moreno-Bueno, Javier de Castro, Inmaculada Ibánez de Cáceres
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Glioblastoma (GB) is a devastating tumor of the central nervous system characterized by a poor prognosis. One of the best-established predictive biomarker in IDH-wildtype GB is O6-methylguanine-DNA methyltransferase (MGMT) methylation (mMGMT
Externí odkaz:
https://doaj.org/article/e4a8484a046145d48a70e38e2c8d1575
Autor:
Aida Bao-Caamano, Nicolás Costa-Fraga, Laure Cayrefourcq, María Amalia Jácome, Aitor Rodriguez-Casanova, Laura Muinelo-Romay, Rafael López-López, Catherine Alix-Panabières, Angel Díaz-Lagares
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-6 (2023)
Externí odkaz:
https://doaj.org/article/44019a23518246d4a7b586d1515e260a
Autor:
Aida Bao-Caamano, Nicolás Costa-Fraga, Laure Cayrefourcq, María Amalia Jácome, Aitor Rodriguez-Casanova, Laura Muinelo-Romay, Rafael López-López, Catherine Alix-Panabières, Angel Díaz-Lagares
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Circulating tumor cells (CTCs) and epigenetic alterations are involved in the development of metastasis from solid tumors, such as colorectal cancer (CRC). The aim of this study was to characterize the DNA methylation profile of metastasis-c
Externí odkaz:
https://doaj.org/article/2304ed0bba8b4a78b5de826694fac47d
Autor:
Aida Bao-Caamano, Nicolás Costa-Fraga, Laure Cayrefourcq, Aitor Rodriguez-Casanova, Laura Muinelo-Romay, Rafael López-López, Catherine Alix-Panabières, Angel Díaz-Lagares
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Therapy resistance is a major challenge in colorectal cancer management. Epigenetic changes, such as DNA methylation, in tumor cells are involved in the development of acquired resistance during treatment. Here, we characterized the DNA methylation l
Externí odkaz:
https://doaj.org/article/3311d8b182854d40b440c79ad475453a
Autor:
Aitor Rodriguez-Casanova, Nicolas Costa-Fraga, Clara Castro-Carballeira, Miriam González-Conde, Carmen Abuin, Aida Bao-Caamano, Tomás García-Caballero, Elena Brozos-Vazquez, Carmela Rodriguez-López, Victor Cebey, Patricia Palacios, Juan F. Cueva, Rafael López-López, Clotilde Costa, Angel Díaz-Lagares
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Breast cancers of the luminal B subtype are frequent tumors with high proliferation and poor prognosis. Epigenetic alterations have been found in breast tumors and in biological fluids. We aimed to profile the cell-free DNA (cfDNA) methylome of metas
Externí odkaz:
https://doaj.org/article/eed70f27ab04426b97329ccbc70f0e54
Autor:
Patricia Mondelo-Macía, Carmela Rodríguez-López, Laura Valiña, Santiago Aguín, Luis León-Mateos, Jorge García-González, Alicia Abalo, Oscar Rapado-González, Mercedes Suárez-Cunqueiro, Angel Díaz-Lagares, Teresa Curiel, Silvia Calabuig-Fariñas, Aitor Azkárate, Antònia Obrador-Hevia, Ihab Abdulkader, Laura Muinelo-Romay, Roberto Diaz-Peña, Rafael López-López
Publikováno v:
Cells, Vol 9, Iss 2, p 522 (2020)
MET alterations may provide a potential biomarker to evaluate patients who will benefit from treatment with MET inhibitors. Therefore, the purpose of the present study is to investigate the utility of a liquid biopsy-based strategy to assess MET alte
Externí odkaz:
https://doaj.org/article/8a077cddf3f24975be87c0ac39fd7b8c
Autor:
Juan Ruiz-Bañobre, Aitor Rodriguez-Casanova, Nicolas Costa-Fraga, Aida Bao-Caamano, Ana Alvarez-Castro, Martín Carreras-Presas, Elena Brozos-Vazquez, Yolanda Vidal-Insua, Francisca Vazquez-Rivera, Sonia Candamio-Folgar, Manuel Mosquera-Presedo, Ramón M. Lago-Lestón, Laura Muinelo-Romay, José Ángel Vázquez-Bueno, Rebeca Sanz-Pamplona, Víctor Moreno, Ajay Goel, Lourdes Castillo, Ana C. Martin, Rocio Arroyo, Manel Esteller, Ana B. Crujeiras, Rafael López-López, Angel Díaz-Lagares
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
J.R.-B. has received honoraria for educational activities from Roche; honoraria for consultancies from Boehringer Ingelheim; institutional research funding from Roche; and travel, accommodations, expenses from Bristol-Myers Squibb, Merck Sharp & Dohm
Autor:
José Pedro Sequeira, Sofia Salta, Rui Freitas, Rafael López-López, Ángel Díaz-Lagares, Rui Henrique, Carmen Jerónimo
Publikováno v:
Cancers, Vol 16, Iss 7, p 1363 (2024)
Background: Prostate cancer (PCa) is one of the most frequently occurring malignancies. Although most cases are not life-threatening, approximately 20% endure an unfavorable outcome. PSA-based screening reduced mortality but at the cost of an increas
Externí odkaz:
https://doaj.org/article/11eb7f646f01454899974f11217dbafd
Autor:
Óscar Rapado‐González, Jenifer Brea‐Iglesias, Aitor Rodríguez‐Casanova, Aida Bao‐Caamano, José‐Luis López‐Cedrún, Gabriel Triana‐Martínez, Roberto Díaz‐Peña, María Arminda Santos, Rafael López‐López, Laura Muinelo‐Romay, Mónica Martínez‐Fernández, Ángel Díaz‐Lagares, María Mercedes Suárez‐Cunqueiro
Publikováno v:
Cancer Medicine, Vol 12, Iss 6, Pp 6615-6622 (2023)
Abstract Background We explore the utility of TruSight Tumor 170 panel (TST170) for detecting somatic mutations in tumor and cfDNA from locoregional recurrent and/or metastatic head and neck squamous cell carcinoma (HNSCC). Methods Targeted NGS of tu
Externí odkaz:
https://doaj.org/article/bbbfa19ced1e489ba1715372d5264455
Autor:
Mónica, Macías, Estibaliz, Alegre, Angel, Díaz-Lagares, Ana, Patiño, Jose L, Pérez-Gracia, Miguel, Sanmamed, Rafael, López-López, Nerea, Varo, Alvaro, González
Publikováno v:
Advances in clinical chemistry. 83
Liquid biopsy refers to the molecular analysis in biological fluids of nucleic acids, subcellular structures, especially exosomes, and, in the context of cancer, circulating tumor cells. In the last 10 years, there has been an intensive research in l