Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Angel Cooper"'
Autor:
Robert Maroko, Mary Beth Sabol, Nathalie Castaing, Gary Dukart, Regöly-Mérei J, John M. Embil, Jean Yan, Zsófia Ozsvár, Laszlo Lauf, Nathalie Dartois, Ismael Mitha, Angel Cooper
Publikováno v:
Diagnostic Microbiology and Infectious Disease. 78(4):469-480
A phase 3, randomized, double-blind trial was conducted in subjects with diabetic foot infections without osteomyelitis (primary study) or with osteomyelitis (substudy) to determine the efficacy and safety of parenteral (intravenous [iv]) tigecycline
Publikováno v:
The Open Respiratory Medicine Journal
Introduction: This study was conducted to evaluate the efficacy of tigecycline (TGC) versus levofloxacin (LEV) in hospitalized patients with community-acquired pneumonia (CAP) using pooled data and to perform exploratory analyses of risk factors asso
Autor:
Jeffrey P. Hammel, Paul G. Ambrose, Joan M. Korth-Bradley, Christopher M. Rubino, C. Angel Cooper, Sujata M. Bhavnani, Nathalie Dartois, Alan Forrest
Publikováno v:
Antimicrobial Agents and Chemotherapy. 56:1065-1072
Pharmacokinetic and clinical data from tigecycline-treated patients with hospital-acquired pneumonia (HAP) who were enrolled in a phase 3 clinical trial were integrated in order to evaluate pharmacokinetic-pharmacodynamic (PK-PD) relationships for ef
Autor:
Alan Forrest, Nathalie Dartois, Christopher M. Rubino, Paul G. Ambrose, Angel Cooper, Joan M. Korth-Bradley, Sujata M. Bhavnani, Gary Dukart
Publikováno v:
Antimicrobial Agents and Chemotherapy. 56:130-136
Exposure-response analyses for efficacy and safety were performed for tigecycline-treated patients suffering from community-acquired pneumonia. Data were collected from two randomized, controlled clinical trials in which patients were administered a
Autor:
Chia Ming Chang, B. Nagari, Angel Cooper, Vishwanath Pai, Nathalie Dartois, Sylvie Jouve, Sacchidanand Sarvajnamurthy Aradhya, Yin Ching Chuang
Publikováno v:
Journal of Microbiology, Immunology and Infection. 44(2):116-124
Background To compare the monotherapy of tigecycline with vancomycin-aztreonam in hospitalized patients from India and Taiwan with complicated skin and skin structure infections (cSSSIs). Methods Safety and efficacy data were analyzed for Indian ( n
Autor:
Krasimir, Vasilev, Galina, Reshedko, Remus, Orasan, Miguel, Sanchez, Juri, Teras, Tim, Babinchak, Gary, Dukart, Angel, Cooper, Nathalie, Dartois, Hassan, Gandjini, Russ, Orrico, Evelyn, Ellis-Grosse, Silvestrs, Zebolds
Publikováno v:
Journal of Antimicrobial Chemotherapy. 62:i29-i40
Objectives To evaluate the efficacy and safety of tigecycline in patients with selected serious infections caused by resistant Gram-negative bacteria, or failures who had received prior antimicrobial therapy or were unable to tolerate other appropria
Autor:
Cristina, Tanaseanu, Carlos, Bergallo, Osvaldo, Teglia, Abel, Jasovich, Maria Eugenia, Oliva, Gary, Dukart, Nathalie, Dartois, C Angel, Cooper, Hassan, Gandjini, Rajiv, Mallick, Marius, Zolubas
Publikováno v:
Diagnostic Microbiology and Infectious Disease. 61:329-338
Tigecycline (TGC), a glycylcycline, has expanded activity against Gram-positive and Gram-negative, anaerobic, and atypical bacteria. Two phase 3 studies were conducted. Hospitalized patients with community-acquired pneumonia (CAP) were randomized to
Autor:
Michael H. Metzler, Angel Cooper, Wedad Kassira, Mary C. McCarthy, Manjari Joshi, Stephen E. Olvey
Publikováno v:
Respiratory Medicine. 100:1554-1565
Summary This randomized, double-blind, multicenter study compared the efficacy and safety of piperacillin/tazobactam (P/T) and imipenem/cilastatin (IMP), both in combination with an aminoglycoside, in hospitalized patients with acute nosocomial pneum
Autor:
Alan Forrest, Christopher M. Rubino, Angel Cooper, Paul G. Ambrose, Joan M. Korth-Bradley, Sujata M. Bhavnani, Gary Dukart
Publikováno v:
Antimicrobial agents and chemotherapy. 54(12)
Tigecycline is a new-generation of tetracycline (glycylcyclines) and is active in vitro against bacteria that possess any of the classical genes that confer tetracycline resistance through ribosomal protection or efflux pumps. Herein, tigecycline dis
Autor:
Jianwei Bi, Dawei Liu, Yunsong Yu, Rong Li, Zhiyong Wu, Xiaochun Ma, Lunan Yan, Angel Cooper, Yingyuan Zhang, Xiaoping Chen, Xisheng Leng, Jufang Wu, Junming Wei, Zhiwei Quan, Zhangjing Chen, Robert Maroko
Publikováno v:
BMC Infectious Diseases, Vol 10, Iss 1, p 217 (2010)
BMC Infectious Diseases
BMC Infectious Diseases
Background Tigecycline, a first-in-class broad-spectrum glycylcycline antibiotic, has broad-spectrum in vitro activity against bacteria commonly encountered in complicated intra-abdominal infections (cIAIs), including aerobic and facultative Gram-pos