Zobrazeno 1 - 10
of 530
pro vyhledávání: '"Angel Cogolludo"'
Autor:
Maria Callejo, Daniel Morales-Cano, Miguel A. Olivencia, Gema Mondejar-Parreño, Bianca Barreira, Olga Tura-Ceide, Victor G. Martínez, Alvaro Serrano-Navarro, Laura Moreno, Nick Morrell, Frédéric Perros, Angeles Vicente, Angel Cogolludo, Francisco Perez-Vizcaino
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Vitamin D (vitD) deficiency is frequently observed in patients with pulmonary arterial hypertension (PAH) and, in these patients, low levels of vitD correlate with worse prognosis. The aim of this study was to examine the expression and the
Externí odkaz:
https://doaj.org/article/fa920e63fd7a42c59535f8317860e93e
Autor:
Marta Villegas-Esguevillas, Suhan Cho, Alba Vera-Zambrano, Jae Won Kwon, Bianca Barreira, Göcken Telli, Jorge Navarro-Dorado, Daniel Morales-Cano, Beatriz de Olaiz, Laura Moreno, Iain Greenwood, Francisco Pérez-Vizcaíno, Sung Joon Kim, Belén Climent, Angel Cogolludo
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 164, Iss , Pp 114952- (2023)
KV7 channels exert a pivotal role regulating vascular tone in several vascular beds. In this context, KV7 channel agonists represent an attractive strategy for the treatment of pulmonary arterial hypertension (PAH). Therefore, in this study, we have
Externí odkaz:
https://doaj.org/article/654d370cd171423a90808aec78743b58
Autor:
Daniel Morales-Cano, Jose Luis Izquierdo-García, Bianca Barreira, Sergio Esquivel-Ruiz, Maria Callejo, Rachele Pandolfi, Palmira Villa-Valverde, Ignacio Rodríguez, Angel Cogolludo, Jesus Ruiz-Cabello, Francisco Perez-Vizcaino, Laura Moreno
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/29cf998c7b394a7c8ccb2b05200ccfd7
Autor:
Alba Vera-Zambrano, Maria Baena-Nuevo, Susanne Rinné, Marta Villegas-Esguevillas, Bianca Barreira, Gokcen Telli, Angela de Benito-Bueno, José Antonio Blázquez, Belén Climent, Francisco Pérez-Vizcaino, Carmen Valenzuela, Niels Decher, Teresa Gonzalez, Angel Cogolludo
Publikováno v:
Pharmacological Research, Vol 189, Iss , Pp 106684- (2023)
KV1.5 channels are key players in the regulation of vascular tone and atrial excitability and their impairment is associated with cardiovascular diseases including pulmonary arterial hypertension (PAH) and atrial fibrillation (AF). Unfortunately, pha
Externí odkaz:
https://doaj.org/article/669cefd33c57474f939a3f93d47c212f
Autor:
Daniel Morales-Cano, Jose Luis Izquierdo-García, Bianca Barreira, Sergio Esquivel-Ruiz, Maria Callejo, Rachele Pandolfi, Palmira Villa-Valverde, Ignacio Rodríguez, Angel Cogolludo, Jesus Ruiz-Cabello, Francisco Perez-Vizcaino, Laura Moreno
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Despite increasing evidence suggesting that pulmonary arterial hypertension (PAH) is a complex disease involving vasoconstriction, thrombosis, inflammation, metabolic dysregulation and vascular proliferation, all the drugs approved for PA
Externí odkaz:
https://doaj.org/article/2dc11ae4e5a5425a8f6d21bbeb898625
Autor:
Rahul Kumar, Öznur Aktay-Cetin, Vaughn Craddock, Daniel Morales-Cano, Djuro Kosanovic, Angel Cogolludo, Francisco Perez-Vizcaino, Sergey Avdeev, Ashok Kumar, Anil Kumar Ram, Stuti Agarwal, Ananya Chakraborty, Rajkumar Savai, Vinicio de Jesus Perez, Brian B Graham, Ghazwan Butrous, Navneet K Dhillon
Publikováno v:
PLoS Pathogens, Vol 19, Iss 1, p e1011063 (2023)
The Coronavirus Disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and its sublineages pose a new challenge to healthcare systems worldwide due to its ability to efficiently spread in immunized populations
Externí odkaz:
https://doaj.org/article/9b110a173dd444aebc53dc7fefe8314d
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The dysregulation of K+ channels is a hallmark of pulmonary arterial hypertension (PAH). Herein, the channelome was analyzed in lungs of patients with PAH in a public transcriptomic database. Sixty six (46%) mRNA encoding cationic channels w
Externí odkaz:
https://doaj.org/article/40c07f33681c45b986b8384fe5b327e7
Autor:
Sandra Medrano-Garcia, Daniel Morales-Cano, Bianca Barreira, Alba Vera-Zambrano, Rahul Kumar, Djuro Kosanovic, Ralph Theo Schermuly, Brian B. Graham, Francisco Perez-Vizcaino, Alistair Mathie, Rajkumar Savai, Soni Pullamseti, Ghazwan Butrous, Edgar Fernández-Malavé, Angel Cogolludo
Publikováno v:
Cells, Vol 11, Iss 15, p 2414 (2022)
HIV and Schistosoma infections have been individually associated with pulmonary vascular disease. Co-infection with these pathogens is very common in tropical areas, with an estimate of six million people co-infected worldwide. However, the effects o
Externí odkaz:
https://doaj.org/article/ea63a3af06fc4a9ead50b0c65617d7ab
Autor:
Arantza Lamas-Paz, Laura Morán, Jin Peng, Beatriz Salinas, Nuria López-Alcántara, Svenja Sydor, Ramiro Vilchez-Vargas, Iris Asensio, Fengjie Hao, Kang Zheng, Beatriz Martín-Adrados, Laura Moreno, Angel Cogolludo, Manuel Gómez del Moral, Lars Bechmann, Eduardo Martínez-Naves, Javier Vaquero, Rafael Bañares, Yulia A. Nevzorova, Francisco Javier Cubero
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Binge drinking, i.e., heavy episodic drinking in a short time, has recently become an alarming societal problem with negative health impact. However, the harmful effects of acute alcohol injury in the gut-liver axis remain elusive. Hence, we focused
Externí odkaz:
https://doaj.org/article/4b3c3c37d791403e8a308038071f525c
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Lung diseases constitute a global health concern causing disability. According to WHO in 2016, respiratory diseases accounted for 24% of world population mortality, the second cause of death after cardiovascular diseases. The Kv7 channels family is a
Externí odkaz:
https://doaj.org/article/e26d94b71bde4c1996e299c8f02618ea