Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Angel Cayo"'
Autor:
Ricardo Huilcaman, Whitney Venturini, Lucia Fuenzalida, Angel Cayo, Raul Segovia, Claudio Valenzuela, Nelson Brown, Rodrigo Moore-Carrasco
Publikováno v:
Cells, Vol 11, Iss 6, p 1014 (2022)
Platelets play important roles in thrombosis-dependent obstructive cardiovascular diseases. In addition, it has now become evident that platelets also participate in the earliest stages of atherosclerosis, including the genesis of the atherosclerotic
Externí odkaz:
https://doaj.org/article/a16ea4e00a6a473aa1ed0acdbb11c5d6
Autor:
Rafael Zúñiga, Guierdy Concha, Angel Cayo, Rocio Cikutović-Molina, Bárbara Arevalo, Wendy González, Marcelo A. Catalán, Leandro Zúñiga
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 129, Iss , Pp 110383- (2020)
Withaferin A (WFA), a C5,C6-epoxy steroidal lactone isolated from the medicinal plant Withania somnifera (L.) Dunal, inhibits growth of tumor cells in different cancer types. However, the mechanisms underlying the effect of WFA on tumor cells are not
Externí odkaz:
https://doaj.org/article/86523dc3b11a4132869f526ea044d636
Publikováno v:
OncoTargets and Therapy. 15:783-797
Potassium (K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3831ae3df0add387cc1d5e2b1892abe
https://doi.org/10.2147/ott.s326614
https://doi.org/10.2147/ott.s326614
Autor:
Bárbara Arévalo, Verónica García-Castillo, Carlos Pérez-Plasencia, Margarita Gutiérrez, Rebeca Salgado-García, Nelson E. Brown, Alexandra Olate-Briones, Francisco Valdes, Claudio Valenzuela, Angel Cayo
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 22:1414-1425
Background: Adenosine is a natural nucleoside present in a variety of organs and tissues, where it acts as a modulator of diverse physiological and pathophysiological processes. These actions are mediated by at least four G protein-coupled receptors,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::630fad045cd1685806fc4e79944f09ac
https://doi.org/10.2174/1871520621666210528151818
https://doi.org/10.2174/1871520621666210528151818
Autor:
Bárbara Arévalo, Mauricio Bedoya, Aytug K. Kiper, Fernando Vergara, David Ramírez, Yuliet Mazola, Daniel Bustos, Rafael Zúñiga, Rocio Cikutovic, Angel Cayo, Susanne Rinné, M. Teresa Ramirez-Apan, Francisco V. Sepúlveda, Oscar Cerda, Eduardo López-Collazo, Niels Decher, Leandro Zúñiga, Margarita Gutierrez, Wendy González
Publikováno v:
Journal of medicinal chemistry. 65(22)
Chemical structures of selective blockers of TASK channels contain aromatic groups and amide bonds. Using this rationale, we designed and synthesized a series of compounds based on 3-benzamidobenzoic acid. These compounds block TASK-1 channels by bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::443847c04aa0a95094aa8f52a2e9c2ee
https://pubmed.ncbi.nlm.nih.gov/36378530
https://pubmed.ncbi.nlm.nih.gov/36378530
Autor:
Angel Cayo, Whitney Venturini, Danitza Rebolledo-Mira, Rodrigo Moore-Carrasco, Andrés A. Herrada, Estefanía Nova-Lamperti, Claudio Valenzuela, Nelson E. Brown
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9284
Despite not dividing, senescent cells acquire the ability to synthesize and secrete a plethora of bioactive molecules, a feature known as the senescence-associated secretory phenotype (SASP). In addition, senescent cells often upregulate autophagy, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120801459f3437679e73f7b0a23e603d
https://doi.org/10.3390/ijms24119284
https://doi.org/10.3390/ijms24119284
Autor:
Claudio A. Valenzuela, Danitza Rebolledo, Angel Cayo, Whitney Venturini, Raúl Segovia, Rodrigo Moore-Carrasco, Nelson Brown
Publikováno v:
Cancer Research. 83:5983-5983
Introduction: The initial transition from a proliferative to a senescent state is accompanied by a reduction in the activity of the cyclin-cyclin-dependent kinase (CDK) complexes, which in turn could be explained by the activation of the p53-p21CIP1/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::771ec0090e044d3339da192efc00ba22
https://doi.org/10.1158/1538-7445.am2023-5983
https://doi.org/10.1158/1538-7445.am2023-5983
Autor:
Angel Cayo, Marcelo A. Catalán, Rocio Cikutović-Molina, Guierdy Concha, Bárbara Arévalo, Wendy González, Leandro Zúñiga, Rafael Zúñiga
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 129, Iss, Pp 110383-(2020)
Withaferin A (WFA), a C5,C6-epoxy steroidal lactone isolated from the medicinal plant Withania somnifera (L.) Dunal, inhibits growth of tumor cells in different cancer types. However, the mechanisms underlying the effect of WFA on tumor cells are not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80afdfd0cd7f2bdc76131e4ca99a367e
http://www.sciencedirect.com/science/article/pii/S075333222030576X
http://www.sciencedirect.com/science/article/pii/S075333222030576X
Autor:
Daniel Mancilla, Claudio Valenzuela, Diego Méndez, Raul Segovia, Rodrigo Moore-Carrasco, Whitney Venturini, Angel Cayo, Eduardo Fuentes, Alexandra Olate-Briones, Nelson E. Brown
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 9
International Journal of Molecular Sciences, Vol 21, Iss 3287, p 3287 (2020)
Volume 21
Issue 9
International Journal of Molecular Sciences, Vol 21, Iss 3287, p 3287 (2020)
Aging is one of the main risk factors for the development of chronic diseases, with both the vascular endothelium and platelets becoming functionally altered. Cellular senescence is a form of permanent cell cycle arrest initially described in primary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::490ad8e3129d70c92a48eb1f30dcfa00
http://europepmc.org/articles/PMC7246568
http://europepmc.org/articles/PMC7246568
Autor:
Rodrigo Moore-Carrasco, Claudio Valenzuela, Nelson E. Brown, Whitney Venturini, Angel Cayo, Raul Segovia
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8149, p 8149 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Cellular senescence is a form of proliferative arrest triggered in response to a wide variety of stimuli and characterized by unique changes in cell morphology and function. Although unable to divide, senescent cells remain metabolically active and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::451d8dcfc26fd03ca951768232815595
https://doi.org/10.3390/ijms22158149
https://doi.org/10.3390/ijms22158149