Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Angel C Medina"'
Autor:
Thiago P Leal, Jennifer N French-Kwawu, Mateus H Gouveia, Victor Borda, Miguel Inca-Martinez, Emily A Mason, Andrea RVR Horimoto, Douglas P Loesch, Elif I Sarihan, Mario R Cornejo-Olivas, Luis E Torres, Pilar E Mazzetti-Soler, Carlos Cosentino, Elison H Sarapura-Castro, Andrea Rivera-Valdivia, Angel C Medina, Elena M Dieguez, Víctor E Raggio, Andrés Lescano, Vitor Tumas, Vanderci Borges, Henrique B Ferraz, Carlos R Rieder, Artur Schumacher-Schuh, Bruno L Santos-Lobato, Carlos Velez-Pardo, Marlene Jimenez-Del-Rio, Francisco Lopera, Sonia Moreno, Pedro Chana-Cuevas, William Fernandez, Gonzalo Arboleda, Humberto Arboleda, Carlos E Arboleda Bustos, Dora Yearout, Maria F Lima-Costa, Eduardo Tarazona, Cyrus Zabetian, Timothy A Thornton, Timothy D O’Connor, Ignacio F Mata
Publikováno v:
medRxiv
Sex differences in Parkinson Disease (PD) risk are well-known. However, it is still unclear the role of sex chromosomes in the development and progression of PD. We performed the first X-chromosome Wide Association Study (XWAS) for PD risk in Latin A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::611448199f677e7660d221b8a0d775d6
https://europepmc.org/articles/PMC9915833/
https://europepmc.org/articles/PMC9915833/
Autor:
Ignacio F. Mata, Artur F. Schumacher-Schuh, Carlos Velez-Pardo, Gonzalo Arboleda, Emily Mason, Andrea R. V. R. Horimoto, Elif Irem Sarihan, Bruno Lopes Santos-Lobato, Carlos Roberto de Mello Rieder, Dora Yearout, Angel C. Medina, Elison Sarapura-Castro, Pedro Chana-Cuevas, Andrea Rivera-Valdivia, Carlos Cosentino, Timothy D. O’Connor, Sonia Moreno, Víctor Raggio, Cyrus P. Zabetian, Timothy A. Thornton, Vitor Tumas, Mario Cornejo-Olivas, Marlene Jimenez-Del-Rio, Miguel Inca-Martinez, Vanderci Borges, Pilar Mazzetti, Carlos E. Arboleda-Bustos, Douglas Loesch, Francisco Lopera, Luis Torres, Humberto Arboleda, Henrique Ballalai Ferraz, Elena Dieguez, William Fernandez, Andres G. Lescano
BackgroundLarge-scale Parkinson’s disease (PD) genome-wide association studies (GWAS) and meta-analyses have, until recently, only been conducted on subjects with European-ancestry. Consequently, polygenic risk scores (PRS) constructed using PD GWA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::901d5d3a600be69a23d909c2aaeca919
https://doi.org/10.1101/2021.11.09.21265082
https://doi.org/10.1101/2021.11.09.21265082
Autor:
Carlos E. Arboleda-Bustos, Douglas Loesch, Paul Cannon, Francisco Lopera, Carlos Cosentino, Andrea Rivera-Valdivia, Carlos Velez-Pardo, Cyrus P. Zabetian, Mario Cornejo-Olivas, Ignacio F. Mata, Sonia Moreno, Karl Heilbron, Carlos Roberto de Mello Rieder, Miguel Inca-Martinez, Andrea R. V. R. Horimoto, Pilar Mazzetti, Luis Torres, Vanderci Borges, Dora Yearout, Elison Sarapura-Castro, Gonzalo Arboleda, Timothy D. O’Connor, Artur F. Schumacher-Schuh, Elif Irem Sarihan, Bruno Lopes Santos-Lobato, Vitor Tumas, Marlene Jimenez-Del-Rio, Pedro Chana-Cuevas, William Fernandez, Emily Mason, Andres G. Lescano, Humberto Arboleda, Elena Dieguez, Henrique Ballalai Ferraz, Angel C. Medina, Timothy A. Thornton, Víctor Raggio
Publikováno v:
Ann Neurol
OBJECTIVE This work was undertaken in order to identify Parkinson's disease (PD) risk variants in a Latino cohort, to describe the overlap in the genetic architecture of PD in Latinos compared to European-ancestry subjects, and to increase the divers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c7df57c1d86c1d1326a1208b2e1c60d
https://pubmed.ncbi.nlm.nih.gov/34476843
https://pubmed.ncbi.nlm.nih.gov/34476843
Autor:
Andrea Rivera-Valdivia, Carlos Roberto de Mello Rieder, Víctor Raggio, Emily Mason, Miguel Inca-Martinez, William Fernandez, Angel C. Medina, Paul Cannon, Henrique Ballalai Ferraz, Andres G. Lescano, Pilar Mazzetti, Karl Heilbron, Sonia Moreno, Gonzalo Arboleda, Humberto Arboleda, Timothy D. O’Connor, Carlos E. Arboleda-Bustos, Vanderci Borges, Timothy A. Thornton, Ignacio F. Mata, Bruno Lopes Santos-Lobato, Pedro Chana-Cuevas, Carlos Velez-Pardo, Vitor Tumas, Elena Dieguez, Cyrus P. Zabetian, Douglas Loesch, Francisco Lopera, Marlene Jimenez-Del-Rio, Luis Torres, Dora Yearout, Mario Cornejo-Olivas, Elif Irem Sarihan, Carlos Cosentino, Andrea R. V. R. Horimoto, Elison Sarapura-Castro, Artur F. Schumacher-Schuh
To date, over 90 Parkinson’s disease (PD) risk variants have been reported from genome-wide association studies (GWAS). However, these GWAS efforts have been limited to individuals of European and East Asian ancestry. We performed the first GWAS of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::474c573306004b2a7bda8c26bacfcc29
https://doi.org/10.1101/2020.11.09.20227124
https://doi.org/10.1101/2020.11.09.20227124
Autor:
Rodrigo Avello, Greggory J. Wilhoite, Luis Torres, Oscar Acosta, Federico Micheli, Juan Segura-Aguilar, Fernando Díaz-Grez, Olimpio Ortega, Owen A. Ross, Dora Yearout, Carlos Cosentino, Claudia Perandones, Mario Cornejo-Olivas, Victoria Alvarez, Matthew J. Farrer, Marcelo Miranda, Pilar Mazzetti, Luis Lay-Son, Ignacio F. Mata, Carles Vilariño-Güell, Osvaldo Trujillo-Godoy, Victoria Marca, Angel C. Medina, Elena Dieguez, Pablo Venegas, Víctor Raggio, Cyrus P. Zabetian, Carolina Perez-Pastene, Justin A. Bacon
Publikováno v:
PARKINSONISM & RELATED DISORDERS
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Mutations in the LRRK2 gene are the most common genetic cause of Parkinson’s disease, with frequencies displaying a high degree of population-specificity. Although more than 100 coding substitutions have been identified, only seven have been proven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7dea87fa5b6ea62b6b5e84465cc332
https://pubmed.ncbi.nlm.nih.gov/21632271
https://pubmed.ncbi.nlm.nih.gov/21632271