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Autor:
Jolene A Bradford, Laura G. Rico, Jordi Junca, Jorge Bardina, Angel Bistue-Rovira, Michael D. Ward, Jordi Petriz
Publikováno v:
The Journal of Immunology. 204:145.25-145.25
Background Multiple myeloma (MM) is characterized by malignant plasma cells in the bone marrow with an associated immunosuppressive microenvironment. PD-L1 suppresses immune response and is overexpressed in MM plasma cells and MDSCs. PD-L1 plays an i