Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Angel, Viñuela"'
Autor:
Jean Paul G. Vonsattel, Michael J. Pitman, Stanley Fahn, Angel Viñuela, Peter H.R. Green, Deepak K. Gupta
Publikováno v:
Mov Disord Clin Pract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccfb232bb403d536ba50d0088d8e3a18
https://europepmc.org/articles/PMC7525195/
https://europepmc.org/articles/PMC7525195/
Publikováno v:
Journal of Comparative Neurology. 525:498-512
Clinical trials testing the hypothesis that fetal dopamine grafts would provide antiparkinsonian benefit in patients who had already developed side-effects from their long-terms use of L-dopa revealed, in some cases, the presence of dyskinesias even
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01ede1d1d01c8dce590d6eed5bc93e1b
https://doi.org/10.1002/cne.24081
https://doi.org/10.1002/cne.24081
Autor:
Ole Isacson, Tatyana D. Sotnikova, C. Reske-Nielsen, Angel Viñuela, Raul R. Gainetdinov, Marc G. Caron, M. Patterson, Penelope J. Hallett
Publikováno v:
Brain
OFF-L-dopa dyskinesias have been a surprising side-effect of intrastriatal foetal ventral mesencephalic transplantation in patients with Parkinson's disease. It has been proposed that excessive and unregulated dopaminergic stimulation of host post-sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e5402ad170278e00e84679feec8642
http://europepmc.org/articles/PMC2639209
http://europepmc.org/articles/PMC2639209
Autor:
Jan Pruszak, Thomas Lardaro, Ole Isacson, Wesley Ludwig, Kwang-Soo Kim, Eva Hedlund, Angel Viñuela
Publikováno v:
Stem Cells. 26:1526-1536
Both fetal ventral mesencephalic (VM) and embryonic stem (ES) cell-derived dopamine neurons have been used successfully to correct behavioral responses in animal models of Parkinson's disease. However, grafts derived from fetal VM cells or from ES ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ad97572b8f00a57588a40e7bf8ba029
https://doi.org/10.1634/stemcells.2007-0996
https://doi.org/10.1634/stemcells.2007-0996
Publikováno v:
Neurobiology of Disease, Vol 29, Iss 1, Pp 103-116 (2008)
Surgeries involving transplantation of fetal dopamine (DA) neurons into the caudate-putamen of patients with Parkinson's disease (PD) have been performed in various clinical trials to examine a potential restoration of motor function. The absence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::884ebdb8c7ae7047c4f1849c96fffe3a
https://doi.org/10.1016/j.nbd.2007.08.008
https://doi.org/10.1016/j.nbd.2007.08.008
Autor:
Ole Isacson, Marc G. Caron, Jingping Zhang, Wei-Dong Yao, Angel Viñuela, Seth G. N. Grant, Penelope J. Hallett, Gregory M. Miller, Mark H. Neely
Publikováno v:
Journal of Biological Chemistry. 282:15778-15789
Dopamine D1 receptors play an important role in movement, reward, and learning and are implicated in a number of neurological and psychiatric disorders. These receptors are concentrated in dendritic spines of neurons, including the spine head and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f724116eb5505abd217cf5b09f97fa4
https://doi.org/10.1074/jbc.m611485200
https://doi.org/10.1074/jbc.m611485200
Autor:
Angel Viñuela, Sunghoi Hong, Eva Hedlund, Andrew Ferree, Jan Pruszak, Ole Isacson, Kwang-Soo Kim
Publikováno v:
Stem Cells. 25:1126-1135
Transplantation of mouse embryonic stem (mES) cells can restore function in Parkinson disease models, but can generate teratomas. Purification of dopamine neurons derived from embryonic stem cells by fluorescence-activated cell sorting (FACS) could p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1c9b8c6925f945582bc5c96fbefac4
https://doi.org/10.1634/stemcells.2006-0540
https://doi.org/10.1634/stemcells.2006-0540
Autor:
Coromoto A, Palermo-Garófalo, José H, Martínez, María, de Lourdes Miranda, Radamés, Fernández, Angel, Viñuela
Publikováno v:
Boletin de la Asociacion Medica de Puerto Rico. 103(1)
We report a case of 24 year-old-female presenting with bilateral leg heaviness sensation and difficult walking of one-day duration. Over the past three months she developed progressive and frequent tingling sensation on her hands accompanied by heada
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8492fcae26c8f364599a8402ac0c716b
https://pubmed.ncbi.nlm.nih.gov/21696105
https://pubmed.ncbi.nlm.nih.gov/21696105
Autor:
Oliver Cooper, Casper Reske-Nielsen, Diane C. Lagace, Antoine de Chevigny, Angel Viñuela, Ole Isacson, Amelia J. Eisch
Publikováno v:
STEM CELLS
STEM CELLS, AlphaMed Press, 2008, 26 (9), pp.2349-2360. ⟨10.1634/stemcells.2008-0080⟩
STEM CELLS, AlphaMed Press, 2008, 26 (9), pp.2349-2360. ⟨10.1634/stemcells.2008-0080⟩
Infusion of transforming growth factor α (TGFα) into the adult dopamine (DA)-depleted striatum generates a local population of nestin+/proliferating cell nuclear antigen (PCNA)+ newborn cells. The precise origin and fate of these new striatal cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056cec267651c8cbdc09be607d642484
https://pubmed.ncbi.nlm.nih.gov/18556510
https://pubmed.ncbi.nlm.nih.gov/18556510
Autor:
Rosario Sanchez-Pernaute, Ivar Mendez, Ole Isacson, Alain Dagher, Lars Björklund, Daniela Ferrari, Oliver Cooper, Angel Viñuela
Publikováno v:
Brain : a journal of neurology. 128(Pt 7)
We report the first post-mortem analysis of two patients with Parkinson's disease who received fetal midbrain transplants as a cell suspension in the striatum, and in one case also in the substantia nigra. These patients had a favourable clinical evo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b809a1384a17f3058db652602f0c9eb4
https://pubmed.ncbi.nlm.nih.gov/15980119
https://pubmed.ncbi.nlm.nih.gov/15980119