The scaffolding function of LSD1 controls DNA methylation in mouse ESCs

Autor: Sandhya Malla, Kanchan Kumari, Carlos A. García-Prieto, Jonatan Caroli, Anna Nordin, Trinh T. T. Phan, Devi Prasad Bhattarai, Carlos Martinez-Gamero, Eshagh Dorafshan, Stephanie Stransky, Damiana Álvarez-Errico, Paulina Avovome Saiki, Weiyi Lai, Cong Lyu, Ludvig Lizana, Jonathan D. Gilthorpe, Hailin Wang, Simone Sidoli, Andre Mateus, Dung-Fang Lee, Claudio Cantù, Manel Esteller, Andrea Mattevi, Angel-Carlos Roman, Francesca Aguilo

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)

Abstract Lysine-specific histone demethylase 1 (LSD1), which demethylates mono- or di- methylated histone H3 on lysine 4 (H3K4me1/2), is essential for early embryogenesis and development. Here we show that LSD1 is dispensable for mouse embryonic stem

Externí odkaz: https://doaj.org/article/2d6f847ecfc84532b688deb0fc0250d8

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Comprehensive management of risk factors in peripheral vascular disease. Expert consensus

Autor: Aicart Bort, Mª Dolores, Almagro Múgica, Fátima, Arrarte Esteban, Vicente Ignacio, Ayala Vigueras, Isabel, Barquilla García, Alfonso, Bellido Castañeda, Virginia, Berenguel Senén, Alejandro, Blanco Echevarría, Agustín, Botana López, Manuel Antonio, Brea Hernando, Ángel, Brito Banfiel, Miguel, Calsina Juscafresa, Laura, Cánovas Molina, María Gloria, Carbayo Herencia, Julio Antonio, Carrasco Carrasco, Eduardo, Carro, Amelia, Casañas Martínez, Marta, Castilla-Guerra, Luis, Cepeda Rodrigo, José María, Cinza-Sanjurjo, Sergio, Clarà, Albert, Comas Samper, José Manuel, Cordero, Alberto, Cosin Sales, Juan, de Juan Bagudá, Javier, de la Fuente, Natalia, Delgado, Elías, Doiz Artázcoz, Esther, Durán Martínez, María, Escalada, Javier, Escobar Cervantes, Carlos, Escribano Pardo, Daniel, Estallo Laliena, Luis, Félix Redondo, Francisco Javier, Fernández Pardo, Jacinto, Rodriguez-Lacin, Jose María Fernández, Ferrer García, Juan Carlos, Frías Vargas, Manuel, Galarza Tapia, Andrés, García León, Andrés, García Lerín, Aurora, García-Martín, Lisardo, Gargallo Fernández, Manuel, Gil, Inés Gil, Girbés Borrás, Juan, Guerra Requena, Mercedes, Guijarro Herraiz, Carlos, Hernández Martínez, Antonio Miguel, Hevia, Sergio, Ibarretxe Gerediaga, Daiana, Iborra Ortega, Elena, Jansen Chaparro, Sergio, Jarauta Simón, Estíbaliz, Jericó Alba, Carlos, Jiménez Muñoz, Beatriz, Lahoz, Carlos, Leiva Hernando, Luis, León Mazorra, Magdalena, López Valverde, María Eugenia, Lorente Calvo, Rosario, Martín Cañuelo, Jorge Jesús, Martínez Hervas, Sergio, Martínez López, María Ángeles, Masmiquel, Luis, Matía Cubillo, Ángel Carlos, Medina Falcón, Agustín, Merino Lanza, Esther, Morales-Pérez, Francisco M., Morata Barrado, Pilar Caridad, Moreno-Pérez, Óscar, Morillas Bueno, Miren, Mosquera Lozano, Jose Daniel, Muñiz Grijalvo, Ovidio, Muñoz Rivas, Núria, Navas de Solís, María Soledad, Obaya Rebollar, Juan Carlos, Ortega, Emilio, Pallarés-Carratalá, Vicente, Párraga Martínez, Ignacio, Pascual Fuster, Vicente, Peinado Adiego, Carmen, Pereira López, Eva María, Pérez Lázaro, M. Antonia, Pérez Pérez, Antonio, Pinés Corrales, Pedro J., Polo García, Jose, Prieto Díaz, Miguel Ángel, Quindimil Vázquez, José Antonio, Rama Martínez, Teresa, Reyes García, Rebeca, Ripoll Vera, Tomás, Rodilla Sala, Enrique, Rodríguez Piñero, Manuel, de Buruaga, Víctor Rodríguez Sáenz, Ruiz García, Antonio, Ruiz Ortiz, Martín, Ruiz Palomar, José Manuel, Saltijeral Cerezo, Adriana, Álvarez, Julio Sánchez, Ortiga, Ruth Sánchez, Sánchez-Hernández, Rosa María, Santos Altozano, Carlos, Seoane Vicente, Maria, Suárez Tembra, Manuel, Tejera Pérez, Cristina, Toledo Frías, Pablo Antonio, Turégano Yedro, Miguel, Valdivielso, Pedro, Valls-Roca, Francisco, de Ceniga, Melina Vega, Velasco Valdazo, Elisa, Vidal-Pérez, Rafael, Zamora Cervantes, Alberto, Barrios, V., Beato, P., Brotons, C., Campuzano, R., Merino-Torres, J.F., Mostaza, J.M., Plana, N., Rubio, J.A., Comellas, M. ^*

Publikováno v: In Revista Clínica Española (English Edition) February 2022 222(2):82-90

Esrrb Regulates Specific Feed-Forward Loops to Transit From Pluripotency Into Early Stages of Differentiation

Autor: Amin R. Mazloom, Huilei Xu, Jaume Reig-Palou, Ana Vasileva, Angel-Carlos Román, Sonia Mulero-Navarro, Ihor R. Lemischka, Ana Sevilla

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 10 (2022)

Characterization of pluripotent states, in which cells can both self-renew or differentiate, with the irreversible loss of pluripotency, are important research areas in developmental biology. Although microRNAs (miRNAs) have been shown to play a rele

Externí odkaz: https://doaj.org/article/9157c4114685456a9a9eefd77bed681f

Junctional Adhesion Molecule 3 Expression in the Mouse Airway Epithelium Is Linked to Multiciliated Cells

Autor: Clara Maria Mateos-Quiros, Sergio Garrido-Jimenez, Guadalupe Álvarez-Hernán, Selene Diaz-Chamorro, Juan Francisco Barrera-Lopez, Javier Francisco-Morcillo, Angel Carlos Roman, Francisco Centeno, Jose Maria Carvajal-Gonzalez

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Tight-junction (TJ) proteins are essential for establishing the barrier function between neighbor epithelial cells, but also for recognition of pathogens or cell migration. Establishing the expression pattern and localization of different TJ proteins

Externí odkaz: https://doaj.org/article/3e82c7f8e1964538998287d246b45057