Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Angélica Fierro"'
Autor:
Nicole Morales-Camilo, Jingzhun Liu, Manuel J. Ramírez, Patricio Canales-Salgado, Juan José Alegría, Xuyao Liu, Hui Ting Ong, Nelson P. Barrera, Angélica Fierro, Yusuke Toyama, Benjamin T. Goult, Yilin Wang, Yue Meng, Ryosuke Nishimura, Kedsarin Fong-Ngern, Christine Siok Lan Low, Pakorn Kanchanawong, Jie Yan, Andrea Ravasio, Cristina Bertocchi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Force transmission through adherens junctions (AJs) is crucial for multicellular organization, wound healing and tissue regeneration. Recent studies shed light on the molecular mechanisms of mechanotransduction at the AJs. However, the canon
Externí odkaz:
https://doaj.org/article/6be83a197f51435ca5f41022c5884809
Publikováno v:
ACS Omega, Vol 8, Iss 45, Pp 43051-43059 (2023)
Externí odkaz:
https://doaj.org/article/c8f2e3300ea24f63848e74579df9a3b4
Autor:
Juan Sebastián Reyes, Eduardo Fuentes-Lemus, Juan David Figueroa, Javier Rojas, Angélica Fierro, Felipe Arenas, Per M. Hägglund, Michael J. Davies, Camilo López-Alarcón
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-19 (2022)
Abstract Escherichia coli glucose-6-phosphate dehydrogenase (G6PDH) and 6-phosphogluconate dehydrogenase (6PGDH) are key enzymes of the pentose phosphate pathway, responsible for the NADPH production in cells. We investigated modification of both enz
Externí odkaz:
https://doaj.org/article/39be9749decb4aa08abe21669ea3ffac
Autor:
Jackson J. Alcázar, Edgar Márquez, Luis García-Río, Agustín Robles-Muñoz, Angélica Fierro, José G. Santos, Margarita E. Aliaga
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
The incorporation of a guest, with different basic sites, into an organized system (host), such as macrocycles, could stabilize, detect, or promote the formation of a certain protomer. In this context, this work aimed to study the influence of cucurb
Externí odkaz:
https://doaj.org/article/31e661f0ad1a46d4a09a40b35cf4bfa7
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0220025 (2019)
Recent evidence has raised in discussion the possibility that cannabidiol can act as a negative allosteric modulator of the cannabinoid type 1 receptor. Here we have used computational methods to study the modulation exerted by cannabidiol on the eff
Externí odkaz:
https://doaj.org/article/25e045e7c577499a9022269c3f698669
Autor:
Guillermo Moya-Alvarado, Osvaldo Yañez, Nicole Morales, Angélica González-González, Carlos Areche, Marco Tulio Núñez, Angélica Fierro, Olimpo García-Beltrán
Publikováno v:
Molecules, Vol 26, Iss 9, p 2430 (2021)
Fourteen coumarin-derived compounds modified at the C3 carbon of coumarin with an α,β-unsaturated ketone were synthesized. These compounds may be designated as chalcocoumarins (3-cinnamoyl-2H-chromen-2-ones). Both chalcones and coumarins are recogn
Externí odkaz:
https://doaj.org/article/8f903effeb4b40edab5e349abb2857f4
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
The α7 nicotinic acetylcholine receptor (nAChR) is expressed in neuronal and non-neuronal cells and is involved in several physiopathological processes, and is thus an important drug target. We have designed and synthesized novel piperidine derivati
Externí odkaz:
https://doaj.org/article/11497e245bb74230b03614f1084e828c
Autor:
Gabriel Núñez-Vivanco, Angélica Fierro, Pablo Moya, Patricio Iturriaga-Vásquez, Miguel Reyes-Parada
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200637 (2018)
The study of binding site similarities can be relevant to understand the interaction of different drugs at several molecular targets. The increasing availability of protein crystal structures and the development of novel algorithms designed to evalua
Externí odkaz:
https://doaj.org/article/7b5a8916c3d64e4f868707fda299f4de
Autor:
Angélica Fierro, Dale E Edmondson, Cristian Celis-Barros, Marco Rebolledo-Fuentes, Gerald Zapata-Torres
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154989 (2016)
Despite their structural and chemical commonalities, p-chloro-β-methylphenethylamine and p-methoxy-β-methylphenethylamine display distinct inhibitory and substrate activities upon MAO-B binding. Density Functional Theory (DFT) quantum chemical calc
Externí odkaz:
https://doaj.org/article/a68409f9664e44838779ae299ca83dd6
Autor:
Juan Sebastián Reyes, Eduardo Fuentes-Lemus, Jefferson Romero, Felipe Arenas, Angélica Fierro, Michael J. Davies, Camilo López-Alarcón
Publikováno v:
Free Radical Biology and Medicine. 204:118-127
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::035420e96859f3c244ad43fded73bf55
https://doi.org/10.1016/j.freeradbiomed.2023.04.019
https://doi.org/10.1016/j.freeradbiomed.2023.04.019