Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Angad Garg"'
Publikováno v:
mBio, Vol 15, Iss 7 (2024)
ABSTRACT Inositol pyrophosphates are signaling molecules that regulate cellular phosphate homeostasis in eukaryal taxa. In fission yeast, where the phosphate regulon (comprising phosphate acquisition genes pho1, pho84, and tgp1) is repressed under ph
Externí odkaz:
https://doaj.org/article/412edb847eff4127b4520d45d00b89b1
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT The inositol pyrophosphate signaling molecule 1,5-IP8 is an agonist of RNA 3'-processing and transcription termination in fission yeast that regulates the expression of phosphate acquisition genes pho1, pho84, and tgp1. IP8 is synthesized fr
Externí odkaz:
https://doaj.org/article/7f90611ecad94cb89a6956a2318064ed
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Inositol pyrophosphates (IPPs) are signaling molecules that regulate cellular phosphate homeostasis in diverse eukaryal taxa. In fission yeast, mutations that increase 1,5-IP8 derepress the PHO regulon while mutations that ablate IP8 synthes
Externí odkaz:
https://doaj.org/article/6ba196c8fe054fb58576215ba25bc178
Autor:
Beate Schwer, Angad Garg, Ana M. Sanchez, Mindy A. Bernstein, Bradley Benjamin, Stewart Shuman
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Inositol pyrophosphate (IPP) dynamics govern expression of the fission yeast phosphate homeostasis regulon via their effects on lncRNA-mediated transcription interference. The growth defects (ranging from sickness to lethality) elicited by f
Externí odkaz:
https://doaj.org/article/b4f082a2264149fa8e9145c3bef48d74
Autor:
Angad Garg
Publikováno v:
Bio-Protocol, Vol 11, Iss 20 (2021)
The fission yeast Schizosaccharomyces pombe is an excellent genetically tractable model organism used in the study of conserved eukaryotic cellular biology. One genetic tool in the assessment of gene function is the in vivo overexpression of proteins
Externí odkaz:
https://doaj.org/article/a5fc110a505b48609a3ddcc00c05229c
Publikováno v:
PLoS Genetics, Vol 17, Iss 3, p e1009452 (2021)
Fission yeast Cleavage and Polyadenylation Factor (CPF), a 13-subunit complex, executes the cotranscriptional 3' processing of RNA polymerase II (Pol2) transcripts that precedes transcription termination. The three-subunit DPS sub-complex of CPF, con
Externí odkaz:
https://doaj.org/article/464a5506c2024831a843b39710721e1e
Publikováno v:
mBio, Vol 8, Iss 4 (2017)
ABSTRACT Fission yeast phosphate homeostasis entails transcriptional induction of genes encoding phosphate-mobilizing proteins under conditions of phosphate starvation. Transcription factor Pho7, a member of the Zn2Cys6 family of fungal transcription
Externí odkaz:
https://doaj.org/article/2dddd7a272da41ddb0b48a57202e0fcb
Publikováno v:
Nucleic Acids Research. 51:3094-3115
Inorganic phosphate is an essential nutrient acquired by cells from their environment. Here, we characterize the adaptative responses of fission yeast to chronic phosphate starvation, during which cells enter a state of quiescence, initially fully re
Publikováno v:
Nucleic Acids Research
Expression of fission yeast Pho1 acid phosphatase is repressed under phosphate-replete conditions by transcription of an upstream prt lncRNA that interferes with the pho1 mRNA promoter. lncRNA control of pho1 mRNA synthesis is influenced by inositol
Inorganic polyphosphate (PolyP) is a ubiquitous polymer that plays sundry roles in cell and organismal physiology. Whereas there is evidence for polyphosphate in the cell nucleus, it is unclear whether and how physiological levels of PolyP impact tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2133ffa7af5e53fc44300c303dbef1b
https://doi.org/10.1101/2022.11.28.517416
https://doi.org/10.1101/2022.11.28.517416