Zobrazeno 1 - 10
of 40
pro vyhledávání: '"AngII, angiotensin II"'
Autor:
Carla Cervelli, Franco Marinangeli, Anna Cecilia Carucci, Alessandro Grimaldi, Vincenza Cofini, Chiara Angeletti, Stefano Necozione, Franco Papola, Veronica Biancofiore, Alessia Rosciano
Publikováno v:
Human Immunology
The stimulation of AT1R (Angiotensin II Receptor Type 1) by Angiotensin II has, in addition to the effects on the renin-angiotensin system, also pro-inflammatory effects through stimulation of ADAM17 and subsequent production of INF-gamma and Interle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::072859fa313f38d2ce140b2f398e7d77
https://doi.org/10.1016/j.humimm.2021.10.006
https://doi.org/10.1016/j.humimm.2021.10.006
Autor:
Xin Zeng, Lu Sun, Yan-Hua Du, Cheng-cui Huang, Ming-Ming Ma, Hua-Qing Zheng, Yong-Yuan Guan, Ya-juan Zhang, Xiaofei Lv, Xiao-long Li, Guan-Lei Wang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3994-4007 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Vascular smooth muscle cell (VSMC) migration plays a critical role in the pathogenesis of many cardiovascular diseases. We recently showed that TMEM16A is involved in hypertension-induced cerebrovascular remodeling. However, it is unclear whether thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe2252c02263eb5818f231c5b54829c2
http://www.sciencedirect.com/science/article/pii/S2211383521001416
http://www.sciencedirect.com/science/article/pii/S2211383521001416
Publikováno v:
Saudi Journal of Biological Sciences, Vol 28, Iss 11, Pp 6465-6470 (2021)
Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences
The use of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) in coronavirus disease 2019 (COVID-19) patients has been claimed as associated with the risk of COVID-19 infection and its subsequent morbidities and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73d5f9b3141b315ed573222f71db5af3
http://www.sciencedirect.com/science/article/pii/S1319562X2100574X
http://www.sciencedirect.com/science/article/pii/S1319562X2100574X
Autor:
Hiroyuki Kawagishi, Mitsuhiko Yamada, Cheng-Kun Du, Tsutomu Nakada, Toshihide Kashihara, Sachio Morimoto, Elena E. Wolf, Shin Kadota, Takuro Numaga-Tomita, Yuji Shiba
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • β-arrestin–biased AT1 agonist TRV027 causes a neonatal-specific, long-acting positive inotropic effect with minimum effect on heart rate, oxygen consumption, reactive oxygen species production, and aldosterone s
Highlights • β-arrestin–biased AT1 agonist TRV027 causes a neonatal-specific, long-acting positive inotropic effect with minimum effect on heart rate, oxygen consumption, reactive oxygen species production, and aldosterone s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f2d81ed3d68f51843a352e270a974b
https://soar-ir.repo.nii.ac.jp/records/2001244
https://soar-ir.repo.nii.ac.jp/records/2001244
Autor:
Vera Maria Morsch, Karine Paula Reichert, Milagros Fanny Vera Castro, Naiara Stefanello, Vanessa Valéria Miron, Andréia Machado Cardoso, Maria Rosa Chitolina Schetinger, Charles Elias Assmann, Nathieli B. Bottari
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 137, Iss, Pp 111273-(2021)
Biomedicine & Pharmacotherapy
Biomedicine & Pharmacotherapy
Graphical abstract
Highlights • The coexistence of diabetes and hypertension represents a major risk factor for the onset of cardiovascular problems. • The purinergic signaling pathway constitutes a ubiquitous system of cell–cell communica
Highlights • The coexistence of diabetes and hypertension represents a major risk factor for the onset of cardiovascular problems. • The purinergic signaling pathway constitutes a ubiquitous system of cell–cell communica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34db00a41121e428fb7b9d4795d39e99
http://www.sciencedirect.com/science/article/pii/S0753332221000585
http://www.sciencedirect.com/science/article/pii/S0753332221000585
Autor:
Jonathan Snell
Publikováno v:
The American Journal of Emergency Medicine
This review of current literature provides background to the COVID-19 pandemic, as well as an examination of potential pathophysiologic mechanisms behind development of thrombosis and ischemic stroke related to COVID-19. SARS-CoV-2 infection is well-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::496a596ca6ed4c7edadd243b34abf7ad
Autor:
Nor Idayu A. Rahman, Rasel Molla, Akira Sato, Hiroshi Maegawa, Akio Shimizu, Joanne Ern Chi Soh, Mohammad Khusni B Ahmat Amin, Le Kim Chi Nguyen, Masahiro Komeno, Nao Kokami, Mako Yasuda-Yamahara, Shinji Kume, Hisakazu Ogita, Yoshihiro Asano, Xiaoling Pang
Publikováno v:
The Journal of Biological Chemistry
Diabetes mellitus (DM) causes injury to tissues and organs, including to the heart and kidney, resulting in increased morbidity and mortality. Thus, novel potential therapeutics are continuously required to minimize DM-related organ damage. We have p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38e278a406b4efe8fb929d3f147cf014
https://pubmed.ncbi.nlm.nih.gov/33971198
https://pubmed.ncbi.nlm.nih.gov/33971198
Publikováno v:
Mayo Clinic Proceedings
Pernio or chilblains is characterized by erythema and swelling at acral sites (eg, toes and fingers), typically triggered by cold exposure. Clinical and histopathologic features of pernio are well described, but the pathogenesis is not entirely under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5efab0d6fd00dce62f7a2bd4da04fab
http://europepmc.org/articles/PMC7826004
http://europepmc.org/articles/PMC7826004
Autor:
Naijin Zhang, Ying Zhang, Wei Miao, Chuning Shi, Zihan Chen, Boquan Wu, Yuanming Zou, Qiushi Ma, Shilong You, Saien Lu, Xinyue Huang, Jingwei Liu, Jiaqi Xu, Liu Cao, Yingxian Sun
Publikováno v:
Redox Biology
Redox Biology, Vol 50, Iss, Pp 102238-(2022)
Redox Biology, Vol 50, Iss, Pp 102238-(2022)
Oxidative stress-associated endothelial damage is the initiation factor of cardiovascular disease, and protein posttranslational modifications play critical roles in this process. Bcl-2-associated athanogene 3 (BAG3) is a molecular chaperone regulato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2250b473e2726ef6aa17718da1b6494
https://doi.org/10.1016/j.redox.2022.102238
https://doi.org/10.1016/j.redox.2022.102238
Autor:
Drew M, Nassal, Nehal J, Patel, Sathya D, Unudurthi, Rebecca, Shaheen, Jane, Yu, Peter J, Mohler, Thomas J, Hund
Publikováno v:
The Journal of Biological Chemistry
Fibrosis is a pronounced feature of heart disease and the result of dysregulated activation of resident cardiac fibroblasts (CFs). Recent work identified stress-induced degradation of the cytoskeletal protein βIV-spectrin as an important step in CF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::489fe6d1e0962abf301fa87dc4345e10
https://pubmed.ncbi.nlm.nih.gov/34153319
https://pubmed.ncbi.nlm.nih.gov/34153319