The ERK MAP kinase-PEA3/ETV4-MMP-1 axis is operative in oesophageal adenocarcinoma

Autor: Gulmann Christian, Downey Paul, Guo Baoqiang, Keld Richard, Ang Yeng S, Sharrocks Andrew D

Publikováno v: Molecular Cancer, Vol 9, Iss 1, p 313 (2010)

Abstract Background Many members of the ETS-domain transcription factor family are important drivers of tumourigenesis. In this context, their activation by Ras-ERK pathway signaling is particularly relevant to the tumourigenic properties of many ETS

Externí odkaz: https://doaj.org/article/781e1ad23a374745bf35872446103fc8

Open chromatin profiling identifies AP1 as a transcriptional regulator in oesophageal adenocarcinoma

Autor: Britton, Edward, Rogerson, Connor, Mehta, Shaveta, Li, Yaoyong, Li, Xiaodun, OCCAMS Consortium, Fitzgerald, Rebecca C, Ang, Yeng S, Sharrocks, Andrew D

Publikováno v: PLoS Genetics, Vol 13, Iss 8, p e1006879 (2017)
Britton, E, Rogerson, C, Mehta, S, Li, Y, Li, X, OCCAMS consortium, Fitzgerald, R C, Ang, Y & Sharrocks, A 2017, ' Open chromatin profiling identifies AP1 as a transcriptional regulator in oesophageal adenocarcinoma ', PL o S Genetics, vol. 13, no. 8, e1006879 . https://doi.org/10.1371/journal.pgen.1006879

Oesophageal adenocarcinoma (OAC) is one of the ten most prevalent forms of cancer and is showing a rapid increase in incidence and yet exhibits poor survival rates. Compared to many other common cancers, the molecular changes that occur in this disea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f2627f1435674a20b1b2392ec460636
http://europepmc.org/articles/PMC5578490?pdf=render

Erratum to:'Deregulation of the FOXM1 target gene network and its coregulatory partners in oesophageal adenocarcinoma' [Mol Cancer. 2015;14:69.]

Autor: Wiseman, Elizabeth F., Chen, Xi, Han, Namshik, Webber, Aaron, Ji, Zongling, Sharrocks, Andrew D., Ang, Yeng S.

Publikováno v: Wiseman, E F, Chen, X, Han, N, Webber, A, Ji, Z, Sharrocks, A D & Ang, Y S 2016, ' Erratum to : 'Deregulation of the FOXM1 target gene network and its coregulatory partners in oesophageal adenocarcinoma' [Mol Cancer. 2015;14:69.] ', Molecular Cancer, vol. 15, no. 1, 21 . https://doi.org/10.1186/s12943-016-0506-6

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3818::7130ffc4d550f1436e480b9c2068b000
https://uom.elsevierpure.com/en/publications/1fa3b10f-b98f-47cc-a32a-93a8394e0f36

Patients' views on their experience of the delivery of single-sex accommodation within the endoscopy department: is it worth it?

Autor: Wiseman, Elizabeth F., Chatten, Kelly, Shah, Sita, Keld, Richard R., Ang, Yeng S.

Publikováno v: Frontline Gastroenterology; Jan2017, Vol. 8 Issue 1, p13-18, 6p

FOXM1 and polo‑like kinase 1 are co‑ordinately overexpressed in patients with gastric adenocarcinomas.

Autor: Dibb, M., Han, N., Choudhury, J., Hayes, S., Valentine, H., West, C., Sharrocks, A. D., Ang, Yeng S.

Publikováno v: BMC Research Notes; 11/14/2015, Vol. 8, p1-9, 9p, 1 Black and White Photograph, 2 Charts, 2 Graphs