Associations Between Glucose Metabolism Measures and Amyloid-β and Tau Load on PET 14 Years Later: Findings From the Framingham Heart Study.

Autor: van Gils V; Alzheimer Center Limburg, School for Mental Health and Neuroscience, Department of Psychiatry & Neuroscience, Maastricht University, Maastricht, the Netherlands., Tao Q; Department of Pharmacology, Physiology & Biophysics, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.; Slone Epidemiology Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA., Ang TFA; Slone Epidemiology Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.; Department of Anatomy & Neurobiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.; Framingham Heart Study, Boston University Chobanian & Avedisian School of Medicine, Boston, MA., Young CB; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA., Mormino EC; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA., Qiu WQ; Department of Pharmacology, Physiology & Biophysics, Boston University Chobanian & Avedisian School of Medicine, Boston, MA., Visser PJ; Alzheimer Center Limburg, School for Mental Health and Neuroscience, Department of Psychiatry & Neuroscience, Maastricht University, Maastricht, the Netherlands.; Alzheimer Center and Department of Neurology, Amsterdam Neuroscience Campus, VU University Medical Center, Amsterdam, the Netherlands., Au R; Slone Epidemiology Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.; Department of Anatomy & Neurobiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.; Framingham Heart Study, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.; Department of Neurology & Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.; Department of Epidemiology, Boston University School of Public Health, Boston, MA., Jansen WJ; Alzheimer Center Limburg, School for Mental Health and Neuroscience, Department of Psychiatry & Neuroscience, Maastricht University, Maastricht, the Netherlands., Vos SJB; Alzheimer Center Limburg, School for Mental Health and Neuroscience, Department of Psychiatry & Neuroscience, Maastricht University, Maastricht, the Netherlands.

Publikováno v: Diabetes care [Diabetes Care] 2024 Oct 01; Vol. 47 (10), pp. 1787-1793.

The Relationship between Framingham Stroke Risk Profile on Incident Dementia and Alzheimer's Disease: A 40-Year Follow-Up Study Highlighting Female Vulnerability.

Autor: Yuan J; Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, People's Republic of China., Tao Q; Department of Pharmacology, Physiology, and Biophysics, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Framingham Heart Study, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Slone Epidemiology Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Ang TFA; Framingham Heart Study, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Slone Epidemiology Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Department of Anatomy and Neurobiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Liu C; Framingham Heart Study, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Devine S; Framingham Heart Study, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Department of Anatomy and Neurobiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Auerbach SH; Framingham Heart Study, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Mez J; Framingham Heart Study, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Alzheimer's Disease Research Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Farrer LA; Framingham Heart Study, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Alzheimer's Disease Research Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Department of Medicine (Biomedical Genetics), Boston University Chobanian & Avedisian School of Medicine and Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA.; Department of Ophthalmology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Qiu WQ; Department of Pharmacology, Physiology, and Biophysics, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Framingham Heart Study, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Alzheimer's Disease Research Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Au R; Framingham Heart Study, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Slone Epidemiology Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Department of Anatomy and Neurobiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Alzheimer's Disease Research Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Department of Medicine (Biomedical Genetics), Boston University Chobanian & Avedisian School of Medicine and Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA.

Publikováno v: Annals of neurology [Ann Neurol] 2024 Dec; Vol. 96 (6), pp. 1124-1134. Date of Electronic Publication: 2024 Oct 15.

Speech patterns during memory recall relates to early tau burden across adulthood.

Autor: Young CB; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, USA., Smith V; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, USA., Karjadi C; Department of Anatomy & Neurobiology and Framingham Heart Study, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts, USA., Grogan SM; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, USA., Ang TFA; Department of Anatomy & Neurobiology and Framingham Heart Study, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts, USA., Insel PS; Department of Psychiatry, University of California San Francisco, San Francisco, California, USA., Henderson VW; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, USA.; Department of Epidemiology and Population Health, Stanford University, Stanford, California, USA., Sumner M; Department of Linguistics, Stanford University, Stanford, California, USA., Poston KL; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, USA.; Wu Tsai Neuroscience Institute, Stanford University, Stanford, California, USA., Au R; Department of Anatomy & Neurobiology and Framingham Heart Study, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts, USA., Mormino EC; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, USA.; Wu Tsai Neuroscience Institute, Stanford University, Stanford, California, USA.

Publikováno v: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2024 Apr; Vol. 20 (4), pp. 2552-2563. Date of Electronic Publication: 2024 Feb 13.

AI-based differential diagnosis of dementia etiologies on multimodal data.

Autor: Xue C; Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Department of Electrical & Computer Engineering, Boston University, MA, USA., Kowshik SS; Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Faculty of Computing & Data Sciences, Boston University, MA, USA., Lteif D; Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Department of Computer Science, Boston University, MA, USA., Puducheri S; Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Jasodanand VH; Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Zhou OT; Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Walia AS; Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Guney OB; Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Department of Electrical & Computer Engineering, Boston University, MA, USA., Zhang JD; Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; School of Chemistry, University of New South Wales, Sydney, Australia., Pham ST; Department of Radiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Kaliaev A; Department of Radiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Andreu-Arasa VC; Department of Radiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Dwyer BC; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Farris CW; Department of Radiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Hao H; Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China., Kedar S; Departments of Neurology & Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA., Mian AZ; Department of Radiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Murman DL; Department of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE, USA., O'Shea SA; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA., Paul AB; Department of Radiology, Massachusetts General Hospital, Boston, MA, USA., Rohatgi S; Department of Radiology, Massachusetts General Hospital, Boston, MA, USA., Saint-Hilaire MH; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Sartor EA; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Setty BN; Department of Radiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Small JE; Department of Radiology, Lahey Hospital & Medical Center, Burlington, MA, USA., Swaminathan A; Department of Neurology, SSM Health, Madison, WI, USA., Taraschenko O; Department of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE, USA., Yuan J; Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China., Zhou Y; Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China., Zhu S; Department of Neurology, Brigham & Women's Hospital, Boston, MA, USA., Karjadi C; The Framingham Heart Study, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Ang TFA; The Framingham Heart Study, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Department of Anatomy and Neurobiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Bargal SA; Department of Computer Science, Georgetown University, Washington DC, USA., Plummer BA; Department of Computer Science, Boston University, MA, USA., Poston KL; Department of Neurology, Stanford University, Palo Alto, CA, USA., Ahangaran M; Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Au R; Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; The Framingham Heart Study, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Department of Anatomy and Neurobiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Boston University Alzheimer's Disease Research Center, Boston, MA, USA.; Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA., Kolachalama VB; Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Faculty of Computing & Data Sciences, Boston University, MA, USA.; Department of Computer Science, Boston University, MA, USA.; Boston University Alzheimer's Disease Research Center, Boston, MA, USA.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2024 Mar 26. Date of Electronic Publication: 2024 Mar 26.

Maximizing utility of neuropsychological measures in sex-specific predictive models of incident Alzheimer's disease in the Framingham Heart Study.

Autor: Ferretti MT; Institute for Regenerative Medicine (IREM), University of Zurich, Zurich, Switzerland.; Women's Brain Project, Guntershausen, Switzerland., Ding H; Department of Anatomy and Neurobiology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.; The Framingham Heart Study, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Au R; Department of Anatomy and Neurobiology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.; The Framingham Heart Study, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.; Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA.; Slone Epidemiology Center, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Liu C; The Framingham Heart Study, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA., Devine S; Department of Anatomy and Neurobiology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.; The Framingham Heart Study, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Auerbach S; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Mez J; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Gurnani A; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Liu Y; Department of Anatomy and Neurobiology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.; The Framingham Heart Study, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Santuccione A; Women's Brain Project, Guntershausen, Switzerland., Ang TFA; Department of Anatomy and Neurobiology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.; The Framingham Heart Study, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.; Slone Epidemiology Center, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.

Publikováno v: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2024 Feb; Vol. 20 (2), pp. 1112-1122. Date of Electronic Publication: 2023 Oct 26.