Genome-wide association study of copy number variation with lung function identifies a novel signal of association near BANP for forced vital capacity.

Autor: Shrine N; Department of Health Sciences, University of Leicester, University Road, Leicester, LE1 7RH, UK., Tobin MD; Department of Health Sciences, University of Leicester, University Road, Leicester, LE1 7RH, UK.; National Institute for Health Research (NIHR) Leicester Respiratory Biomedical Research Unit, Glenfield Hospital, Leicester, LE3 9QP, UK., Schurmann C; Department of Functional Genomics, University Medicine Greifswald, Interfaculty Institute for Genetics and Functional Genomics, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), partner site Greifswald, 17475, Greifswald, Germany., Soler Artigas M; Department of Health Sciences, University of Leicester, University Road, Leicester, LE1 7RH, UK., Hui J; Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, Australia., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, University of Tampere and Tampere University Hospital, Tampere, 33521, Finland., Raitakari OT; Department of Clinical Physiology, Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku University Hospital, Turku, 20521, Finland., Pennell CE; School of Women's and Infants' Health, The University of Western Australia, Perth, Australia., Ang QW; School of Women's and Infants' Health, The University of Western Australia, Perth, Australia., Strachan DP; Division of Population Health Sciences, St. George's University of London, London, UK., Homuth G; Department of Functional Genomics, University Medicine Greifswald, Interfaculty Institute for Genetics and Functional Genomics, Greifswald, Germany., Gläser S; Department of Internal Medicine B - Pulmonary Medicine, Weaning and Infectious Diseases and Scientific Division of Pneumology and Pneumological Epidemiology, University Medicine Greifswald, Greifswald, Germany., Felix SB; Department of Functional Genomics, University Medicine Greifswald, Interfaculty Institute for Genetics and Functional Genomics, Greifswald, Germany.; Department of Internal Medicine B - Cardiology, University Medicine Greifswald, Greifswald, Germany., Evans DM; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; School of Social and Community Medicine, University of Bristol, Bristol, UK.; University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia., Henderson J; School of Social and Community Medicine, University of Bristol, Bristol, UK., Granell R; School of Social and Community Medicine, University of Bristol, Bristol, UK., Palmer LJ; School of Public Health, University of Adelaide, Adelaide, Australia., Huffman J; Institute of Genetics and Molecular Medicine, University of Edinburgh Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, UK., Hayward C; Institute of Genetics and Molecular Medicine, University of Edinburgh Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, UK., Scotland G; Institute of Genetics and Molecular Medicine, University of Edinburgh Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, UK., Malarstig A; Pfizer Worldwide Research and Development, Sollentuna, Sweden., Musk B; Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, Australia.; Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Australia., James AL; Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, Australia.; Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Nedlands, Australia., Wain LV; Department of Health Sciences, University of Leicester, University Road, Leicester, LE1 7RH, UK. louisewain@leicester.ac.uk.; National Institute for Health Research (NIHR) Leicester Respiratory Biomedical Research Unit, Glenfield Hospital, Leicester, LE3 9QP, UK. louisewain@leicester.ac.uk.

Publikováno v: BMC genetics [BMC Genet] 2016 Aug 11; Vol. 17 (1), pp. 116. Date of Electronic Publication: 2016 Aug 11.

Common variation near ROBO2 is associated with expressive vocabulary in infancy.

Autor: St Pourcain B; 1] Medical Research Council Integrative Epidemiology Unit, University of Bristol, Oakfield House, 15-23 Oakfield Grove, Bristol BS8 2BN, UK [2] School of Oral and Dental Sciences, University of Bristol, Lower Maudlin Street, Bristol BS1 2LY, UK [3] School of Experimental Psychology, University of Bristol, 12a Priory Road, Bristol BS8 1TU, UK [4]., Cents RA; 1] Generation R Study Group, Erasmus MC-University Medical Centre, Postbus 2040, 3000 CA Rotterdam, The Netherlands [2] Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC-University Medical Centre, Postbus 2060, 3000 CB Rotterdam, The Netherlands [3]., Whitehouse AJ; 1] Telethon Kids Institute, Centre for Child Health Research, University of Western Australia, 100 Roberts Road, Subiaco, Western Australia 6008, Australia [2]., Haworth CM; 1] Department of Psychology, University of Warwick, Coventry CV4 7AL, UK [2] Medical Research Council, Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, De Crespigny Park, Denmark Hill, London SE5 8AF, UK [3]., Davis OS; 1] Medical Research Council, Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, De Crespigny Park, Denmark Hill, London SE5 8AF, UK [2] Department of Genetics, Evolution and Environment, UCL, UCL Genetics Institute, Darwin Building, Gower Street, London WC1E 6BT, UK [3]., O'Reilly PF; 1] Medical Research Council, Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, De Crespigny Park, Denmark Hill, London SE5 8AF, UK [2] Department of Epidemiology and Biostatistics, Medical Research Council (MRC) Public Health England (PHE) Centre for Environment and Health, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, UK., Roulstone S; Bristol Speech and Language Therapy Research Unit, University of the West of England, Frenchay Hospital, Frenchay Park Road, BS16 1LE Bristol, UK., Wren Y; Bristol Speech and Language Therapy Research Unit, University of the West of England, Frenchay Hospital, Frenchay Park Road, BS16 1LE Bristol, UK., Ang QW; School of Women's and Infants' Health, University of Western Australia, 374 Bagot Road, Subiaco, Western Australia 6008, Australia., Velders FP; 1] Generation R Study Group, Erasmus MC-University Medical Centre, Postbus 2040, 3000 CA Rotterdam, The Netherlands [2] Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC-University Medical Centre, Postbus 2060, 3000 CB Rotterdam, The Netherlands., Evans DM; 1] Medical Research Council Integrative Epidemiology Unit, University of Bristol, Oakfield House, 15-23 Oakfield Grove, Bristol BS8 2BN, UK [2] School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK [3] University of Queensland Diamantina Institute, Translational Research Institute, University of Queensland, 37 Kent Street Woolloongabba, Queensland 4102, Australia., Kemp JP; 1] Medical Research Council Integrative Epidemiology Unit, University of Bristol, Oakfield House, 15-23 Oakfield Grove, Bristol BS8 2BN, UK [2] School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK [3] University of Queensland Diamantina Institute, Translational Research Institute, University of Queensland, 37 Kent Street Woolloongabba, Queensland 4102, Australia., Warrington NM; 1] School of Women's and Infants' Health, University of Western Australia, 374 Bagot Road, Subiaco, Western Australia 6008, Australia [2] University of Queensland Diamantina Institute, Translational Research Institute, University of Queensland, 37 Kent Street Woolloongabba, Queensland 4102, Australia., Miller L; School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK., Timpson NJ; 1] Medical Research Council Integrative Epidemiology Unit, University of Bristol, Oakfield House, 15-23 Oakfield Grove, Bristol BS8 2BN, UK [2] School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK., Ring SM; 1] Medical Research Council Integrative Epidemiology Unit, University of Bristol, Oakfield House, 15-23 Oakfield Grove, Bristol BS8 2BN, UK [2] School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK., Verhulst FC; Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC-University Medical Centre, Postbus 2060, 3000 CB Rotterdam, The Netherlands., Hofman A; Department of Epidemiology, Erasmus MC-University Medical Centre, Postbus 2040, 3000 CA Rotterdam, The Netherlands., Rivadeneira F; 1] Department of Epidemiology, Erasmus MC-University Medical Centre, Postbus 2040, 3000 CA Rotterdam, The Netherlands [2] Department of Internal Medicine, Erasmus MC-University Medical Centre, Postbus 2040, 3000 CA Rotterdam, The Netherlands., Meaburn EL; Department of Psychological Sciences, Birkbeck, University of London, Malet Street, London WC1E 7HX, UK., Price TS; Institute for Translational Medicine and Therapeutics, University of Pennsylvania School of Medicine, 3400 Civic Center Boulevard, Building 421, Philadelphia, Pennsylvania 19104-5158, USA., Dale PS; Department of Speech and Hearing Sciences, University of New Mexico, 1700 Lomas Boulevard NE Suite 1300, Albuquerque, New Mexico 87131, USA., Pillas D; Department of Epidemiology and Biostatistics, Medical Research Council (MRC) Public Health England (PHE) Centre for Environment and Health, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, UK., Yliherva A; Faculty of Humanities, Logopedics, Child Language Research Center, University of Oulu, BOX 1000, Oulu 90014, Finland., Rodriguez A; 1] Department of Epidemiology and Biostatistics, Medical Research Council (MRC) Public Health England (PHE) Centre for Environment and Health, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, UK [2] Mid Sweden University Department for Psychology/Mittuniversitetet Avdelningen för psykologi, 83125 Östersund, Sweden., Golding J; School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK., Jaddoe VW; 1] Generation R Study Group, Erasmus MC-University Medical Centre, Postbus 2040, 3000 CA Rotterdam, The Netherlands [2] Department of Epidemiology, Erasmus MC-University Medical Centre, Postbus 2040, 3000 CA Rotterdam, The Netherlands [3] Department of Pediatrics, Erasmus MC-University Medical Centre, Postbus 2060, 3000 CB Rotterdam, The Netherlands., Jarvelin MR; 1] Department of Epidemiology and Biostatistics, Medical Research Council (MRC) Public Health England (PHE) Centre for Environment and Health, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, UK [2] Unit of Primary Care, Oulu University Hospital, Kajaanintie 50, PO Box 20, FI-90220, Oulu 90029, Finland [3] Department of Children and Young People and Families, National Institute for Health and Welfare, Aapistie 1, Box 310, FI-90101 Oulu, Finland [4] Institute of Health Sciences, University of Oulu, PO Box 5000, Oulu FI-90014, Finland [5] Biocenter Oulu, University of Oulu, PO Box 5000, Aapistie 5A, OuluFI-90014, Finland., Plomin R; Medical Research Council, Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, De Crespigny Park, Denmark Hill, London SE5 8AF, UK., Pennell CE; School of Women's and Infants' Health, University of Western Australia, 374 Bagot Road, Subiaco, Western Australia 6008, Australia., Tiemeier H; 1] Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC-University Medical Centre, Postbus 2060, 3000 CB Rotterdam, The Netherlands [2] Department of Epidemiology, Erasmus MC-University Medical Centre, Postbus 2040, 3000 CA Rotterdam, The Netherlands [3]., Davey Smith G; 1] Medical Research Council Integrative Epidemiology Unit, University of Bristol, Oakfield House, 15-23 Oakfield Grove, Bristol BS8 2BN, UK [2] School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK.

Publikováno v: Nature communications [Nat Commun] 2014 Sep 16; Vol. 5, pp. 4831. Date of Electronic Publication: 2014 Sep 16.

CNTNAP2 variants affect early language development in the general population.

Autor: Whitehouse AJ; Telethon Institute for Child Health Research, Centre for Child Health Research, University of Western Australia, Perth, Australia. awhitehouse@ichr.uwa.edu.au, Bishop DV, Ang QW, Pennell CE, Fisher SE

Publikováno v: Genes, brain, and behavior [Genes Brain Behav] 2011 Jun; Vol. 10 (4), pp. 451-6. Date of Electronic Publication: 2011 Mar 01.

Maternal life events during pregnancy and offspring language ability in middle childhood: The Western Australian Pregnancy Cohort Study.

Autor: Whitehouse AJ; Telethon Institute for Child Health Research, Centre for Child Health Research, University of Western Australia, Perth, Western Australia, Australia., Robinson M, Zubrick SR, Ang QW, Stanley FJ, Pennell CE

Publikováno v: Early human development [Early Hum Dev] 2010 Aug; Vol. 86 (8), pp. 487-92. Date of Electronic Publication: 2010 Jul 10.