Pharmacological brake-release of mRNA translation enhances cognitive memory

Autor: Walter, Peter, Renslo, Adam, Arkin, Michelle, Sidrauski, C, Acosta-Alvear, D, Khoutorsky, A, Vedantham, P, Hearn, BR, Li, H, Gamache, K, Gallagher, CM, Ang, KKH, Wilson, C

Publikováno v: Walter, Peter; Renslo, Adam; Arkin, Michelle; Sidrauski, C; Acosta-Alvear, D; Khoutorsky, A; et al.(2013). Pharmacological brake-release of mRNA translation enhances cognitive memory. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/7hn2k63r

Phosphorylation of the α-subunit of initiation factor 2 (eIF2) controls protein synthesis by a conserved mechanism. In metazoa, distinct stress conditions activate different eIF2α kinases (PERK, PKR, GCN2, and HRI) that converge on phosphorylating

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::4f4f81bb1c55c3120ab06af011f3687a
http://www.escholarship.org/uc/item/7hn2k63r

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Guidelines for DNA recombination and repair studies: Mechanistic assays of DNA repair processes.

Autor: Klein HL; New York University School of Medicine, Department of Biochemistry and Molecular Pharmacology, New York, NY 10016, USA., Ang KKH; Small Molecule Discovery Center and Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94143, USA., Arkin MR; Small Molecule Discovery Center and Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94143, USA., Beckwitt EC; Program in Molecular Biophysics and Structural Biology, University of Pittsburgh, Pittsburgh, PA 15261, USA.; The University of Pittsburgh Cancer Institute, Hillman Cancer Center, Pittsburgh, PA 15213, USA., Chang YH; Institute of Biochemical Sciences, National Taiwan University, NO. 1, Section 4, Roosevelt Road, Taipei 10617, Taiwan., Fan J; Biological Physics Research Group, Clarendon Laboratory, Department of Physics, University of Oxford, Oxford, OX1 3PU, UK., Kwon Y; Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT 06520, USA.; Department of Biochemistry and Structural Biology, University of Texas Health San Antonio, San Antonio, Texas 78229, USA., Morten MJ; New York University School of Medicine, Department of Biochemistry and Molecular Pharmacology, New York, NY 10016, USA., Mukherjee S; Department of Microbiology and Molecular Genetics, University of California, Davis, CA 95616, USA., Pambos OJ; Biological Physics Research Group, Clarendon Laboratory, Department of Physics, University of Oxford, Oxford, OX1 3PU, UK., El Sayyed H; Biological Physics Research Group, Clarendon Laboratory, Department of Physics, University of Oxford, Oxford, OX1 3PU, UK., Thrall ES; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 250 Longwood Avenue, Boston, MA 02115, USA., Vieira-da-Rocha JP; Department of Microbiology and Molecular Genetics, University of California, Davis, CA 95616, USA., Wang Q; Department of Molecular and Cellular Biochemistry, Indiana University, Bloomington, IN 47405, USA., Wang S; Ecole Normale Supérieure, Institut de Biologie de l'Ecole Normale Supérieure (IBENS), CNRS, INSERM, PSL Research University, 75005 Paris, France.; Institut Jacques Monod, CNRS, UMR7592, University Paris Diderot, Sorbonne Paris Cité F-75205 Paris, France., Yeh HY; Institute of Biochemical Sciences, National Taiwan University, NO. 1, Section 4, Roosevelt Road, Taipei 10617, Taiwan., Biteen JS; Departments of Chemistry and Biophysics, University of Michigan, Ann Arbor, MI 48109, USA., Chi P; Institute of Biochemical Sciences, National Taiwan University, NO. 1, Section 4, Roosevelt Road, Taipei 10617, Taiwan.; Institute of Biological Chemistry, Academia Sinica, 128 Academia Road, Section 2, Nankang, Taipei 11529, Taiwan., Heyer WD; Department of Microbiology and Molecular Genetics, University of California, Davis, CA 95616, USA.; Department of Molecular and Cellular Biology, University of California, Davis, CA 95616, USA., Kapanidis AN; Biological Physics Research Group, Clarendon Laboratory, Department of Physics, University of Oxford, Oxford, OX1 3PU, UK., Loparo JJ; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 250 Longwood Avenue, Boston, MA 02115, USA., Strick TR; Ecole Normale Supérieure, Institut de Biologie de l'Ecole Normale Supérieure (IBENS), CNRS, INSERM, PSL Research University, 75005 Paris, France.; Institut Jacques Monod, CNRS, UMR7592, University Paris Diderot, Sorbonne Paris Cité F-75205 Paris, France.; Programme Equipe Labellisées, Ligue Contre le Cancer, 75013 Paris, France., Sung P; Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT 06520, USA.; Department of Biochemistry and Structural Biology, University of Texas Health San Antonio, San Antonio, Texas 78229, USA., Van Houten B; Program in Molecular Biophysics and Structural Biology, University of Pittsburgh, Pittsburgh, PA 15261, USA.; Program in Molecular Biophysics and Structural Biology, University of Pittsburgh, Pittsburgh, PA 15261, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15261, USA., Niu H; Department of Molecular and Cellular Biochemistry, Indiana University, Bloomington, IN 47405, USA., Rothenberg E; New York University School of Medicine, Department of Biochemistry and Molecular Pharmacology, New York, NY 10016, USA.

Publikováno v: Microbial cell (Graz, Austria) [Microb Cell] 2019 Jan 07; Vol. 6 (1), pp. 65-101. Date of Electronic Publication: 2019 Jan 07.