Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Angélique Feret"'
Autor:
Laurence Dumais, Gilles Ouvry, Laurent Chantalat, Angélique Feret, Sandrine Chambon, Thibaud Portal, Sandrine Talano, Gwenaëlle Duvert, Catherine Soulet, Jean-Marie Arlabosse, Samuel Tabet, Sebastien Daver, Jonathan Pascau, Nicolas Rodeville, Catherine Raffin, Claire Bouix-Peter, Etienne Thoreau
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:1736-1741
Retinoids have a dominant role in topical acne therapy and to date, only RARβ and RARγ dual agonists have reached the market. Given the tissue distribution of RAR isoforms, it was hypothesized that developing RARγ -selective agonists could yield a
Autor:
Craig S. Harris, Isabelle Cardinaud, Feriel Hacini-Rachinel, Nicolas Rodeville, Audrey Beillard, Arnaud Reitz, Marilyne Bourotte, Benoit Deprez, Laetitia Bonnary, Catherine Comino, Corinne Millois, Delphine Spiesse, Claire Bouix-Peter, Denis Duvert, Jean-Guy Boiteau, Jean-Marie Arlabosse, Yushma Bhurruth-Alcor, Anne-Pascale Luzy, Laurent F. Hennequin, Gaëlle Polge, Emmanuel Vial, Loïc Tomas, Samuel Tabet, Kevin Reverse, Arnaud Mathieu, Artur Pinto, Angélique Feret, Karine Bouquet, Gilles Ouvry, Stéphanie Astri, Nicolas Orsini, Jonathan Pascau, Nathalie Taquet, David Piwnica, Patricia Rossio
Publikováno v:
Bioorganic & Medicinal Chemistry. 26:945-956
Targeting the TNFα pathway is a validated approach to the treatment of psoriasis. In this pathway, TACE stands out as a druggable target and has been the focus of in-house research programs. In this article, we present the discovery of clinical cand