Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Angélica Rocha Joaquim"'
Autor:
Bruna Pippi, William Lopes, Paula Reginatto, Fernanda Émili Klein Silva, Angélica Rocha Joaquim, Ricardo José Alves, Gustavo Pozza Silveira, Marilene Henning Vainstein, Saulo Fernandes Andrade, Alexandre Meneghello Fuentefria
Publikováno v:
Saudi Pharmaceutical Journal, Vol 27, Iss 1, Pp 41-48 (2019)
The 8-hydroxyquinoline core is a privileged scaffold for drug design explored to afford novel derivatives endowed with biological activity. Our research aimed at clarifying the antifungal mechanism of action of clioquinol, 8-hydroxy-5-quinolinesulfon
Externí odkaz:
https://doaj.org/article/aaf3bbd021874517860e378ed237f4a9
Autor:
Simone Jacobus Berlitz, Angélica Rocha Joaquim, Alexandre Meneghello Fuentefria, Irene Clemes Külkamp Guerreiro, Débora Assumpção Rocha, Paula Reginatto, Saulo Fernandes de Andrade
Publikováno v:
Letters in Applied Microbiology. 74:395-404
Often associated to the colonization by Candida spp. biofilm, the catheter-related infections are a serious health problem since the absence of a specific therapy. Hence, the main objective of this work was to evaluate the activity of 8-hydroxyquinol
Autor:
Mariana Pies Gionbelli, Saulo Fernandes de Andrade, Marcela Silva Lopes, Grace Gosmann, Angélica Rocha Joaquim, Alexandre Meneghello Fuentefria
Publikováno v:
Journal of Medicinal Chemistry. 64:16349-16379
The search for new antimicrobials is imperative due to the emergent resistance of new microorganism strains. In this context, revisiting known classes like 8-hydroxyquinolines could be an interesting strategy to discover new agents. The 8-hydroxyquin
Autor:
Saulo Fernandes de Andrade, Angélica Rocha Joaquim, Angelo Gava, Evandro Ficagna, L M de Souza, Mário Lettieri Teixeira, J Fiorentin, Marcus André Kurtz Almança, Mariana Pies Gionbelli, Alexandre Meneghello Fuentefria, M A de Chaves
Publikováno v:
Journal of Applied Microbiology. 131:1440-1451
Aim The purpose of this study was to evaluate the in vitro and in vivo efficiency of derivatives of 8-Hydroxyquinoline (8HQ) in controlling the fungus Ilyonectria liriodendri. Methods and results The in vitro tests consisted of assessing its suscepti
Autor:
Saulo Fernandes de Andrade, Mário Lettieri Teixeira, Maycon Antonio de Cesare, Paula Reginatto, Taís Fernanda Andrzejewski Kaminski, Alexandre Meneghello Fuentefria, Marcela Silva Lopes, Angélica Rocha Joaquim, Mariana Pies Gionbelli, Luana Candice Genz Bazana, Maxwel Adriano Abegg
Publikováno v:
New Journal of Chemistry. 45:18158-18170
The oral administration of clioquinol – a potent 8-hydroxyquinoline antimicrobial drug – was forbidden due to suspicion of it being the cause of SMON (subacute myelo-optic-neuropathy) in Japan. However, this adverse effect was only observed in Ja
Autor:
Graziela Vargas Rigo, Angélica Rocha Joaquim, Alexandre José Macedo, Saulo Fernandes de Andrade, Tiana Tasca
Publikováno v:
Bioorganic Chemistry. 125:105912
Trichomoniasis is a neglected parasitic infection, with no oral therapeutic alternatives to overcome the pitfalls of currently approved drugs. In this context, the search for new anti-Trichomonas vaginalis drugs is imperative. Here we report the sele
Autor:
Letícia Fernandes da Rocha, Angélica Rocha Joaquim, Alexandre Meneghello Fuentefria, Saulo Fernandes de Andrade, Bruna Pippi
Publikováno v:
Journal of Medical Microbiology. 70
Introduction. The presence of Candida biofilms in medical devices is a concerning and important clinical issue for haemodialysis patients who require constant use of prosthetic fistulae and catheters. Hypothesis/Gap Statement. This prolonged use incr
Autor:
Saulo Fernandes de Andrade, Fernanda Émili Klein Silva, Angélica Rocha Joaquim, Gustavo Pozza Silveira, Ricardo José Alves, Bruna Pippi, Alexandre Meneghello Fuentefria, Marilene Henning Vainstein, Paula Reginatto, William Lopes
Publikováno v:
Saudi Pharmaceutical Journal, Vol 27, Iss 1, Pp 41-48 (2019)
The 8-hydroxyquinoline core is a privileged scaffold for drug design explored to afford novel derivatives endowed with biological activity. Our research aimed at clarifying the antifungal mechanism of action of clioquinol, 8-hydroxy-5-quinolinesulfon
Autor:
Angélica Rocha Joaquim, Mário Lettieri Teixeira, Alexandre Meneghello Fuentefria, Denise da Silva, Lucia Emanueli Schimith, Mauro Eugênio Medina Nunes, Simone Merkel, Jeferson Luis Franco, Régis Adriel Zanette, Bruna Pippi, S. Fernandes de Andrade
Publikováno v:
Journal of applied microbiologyReferences. 130(6)
Aim The purpose of this study was to evaluate the antifungal activity and toxicological parameters of 8-hydroxyquinoline derivatives PH151 and PH153 using alternative animal models, to understand their behaviour when subjected to in vivo experiments.
Autor:
Marilene Henning Vainstein, Maxwel Adriano Abegg, Laura Minussi Giuliani, Angélica Rocha Joaquim, G R M Machado, Vanessa Zafaneli Bergamo, Letícia Cruz, Alexandre Meneghello Fuentefria, Bruna Pippi, William Lopes, S.F. de Andrade
Publikováno v:
Journal of applied microbiologyReferences. 128(4)
Aim The purpose of this study was to uncover insights into the mechanism of action of the 8-hydroxyquinoline derivatives PH151 and PH153. In addition, with the future perspective of developing a topical drug for the treatment of candidiasis and derma