Výsledky vyhledávání - "Angélica Rocío Borbón Orjuela"

Relevancia de la ancestría para la variabilidad de polimorfismos de las enzimas metabolizadoras de fármacos CYP2C9, CYP2C19 y CYP2D6 en una población multiétnica de Costa Rica

Autor: Angélica Rocío Borbón Orjuela, Humberto Fariñas, ROCIO ORTIZ-LOPEZ, Marisol López-López, Adrián LLerena, Eduardo Tarazona, Fernanda Rodrigues-Soares, Ingrid Fricke-Galindo, NANCY MONROY-JARAMILLO, AUGUSTO ROJAS-MARTINEZ, Enrique Teran

Publikováno v: Revista de Biología Tropical, Volume: 64, Issue: 3, Pages: 1067-1076, Published: SEP 2016
Revista de Biología Tropical; Vol. 64 No. 3 (2016): Volume 64 – Regular number 3 – September 2016
Revista de Biología Tropical; Vol. 64 Núm. 3 (2016): Volumen 64 – Número regular 3 – Setiembre 2016
Revista Biología Tropical; Vol. 64 N.º 3 (2016): Volumen 64 – Número regular 3 – Setiembre 2016
Portal de Revistas UCR
Universidad de Costa Rica
instacron:UCR

CYP2C9, CYP2C19 and CYP2D6 metabolize around 40 % of drugs and their genes vary across populations. The Costa Rican population has a trihybrid ancestry and its key geographic location turns it into a suitable scenario to evaluate interethnic differen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cac2f997fb8e1cb1ebe3de5c553ac31d
http://www.scielo.sa.cr/scielo.php?script=sci_arttext&pid=S0034-77442016000301067&lng=en&tlng=en

Zobrazit plný text záznamu

Evaluation of drug-metabolizing enzyme hydroxylation phenotypes in Hispanic populations: the CEIBA cocktail

Autor: Fernando De Andrés, Angélica Rocío Borbón Orjuela, Manuela Grazina, Pedro Dorado, Addrián Llerena, Adriana Ochoa, ROCIO ORTIZ-LOPEZ, Marisol López-López, Adrián LLerena, Eduardo Tarazona, René Delgado Hernández, Romina Rojas Ponce, NANCY MONROY-JARAMILLO, AUGUSTO ROJAS-MARTINEZ, Enrique Teran

Publikováno v: Drug Metabolism and Drug Interactions. 28

Interindividual differences in response to drug treatments are mainly caused by differences in drug metabolism, in which cytochrome P450 (CYP450) enzymes are involved. Genetic polymorphisms of these enzymes have a key role in this variability. Howeve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa3bf19f6b99b748d85ff2c928fc33b7
https://doi.org/10.1515/dmdi-2013-0020

Zobrazit plný text záznamu

Losartan hydroxylation phenotype in an Ecuadorian population: influence of CYP2C9 genetic polymorphism, habits and gender

Autor: Fernando De Andrés, Angélica Rocío Borbón Orjuela, Manuela Grazina, Pedro Dorado, Addrián Llerena, Adrián LLerena, Eduardo Tarazona, Yadira Xitlalli Perez Paramo, AUGUSTO ROJAS-MARTINEZ, Enrique Teran

Publikováno v: Pharmacogenomics. 13(15)

Aim: To describe for the first time CYP2C9 hydroxylation phenotype with CYP2C9 genotypes in a Hispanic (Ecuadorian) population using losartan; and the relevance of gender, tobacco, ethanol and caffeine consumption on the enzyme hydroxylation capacity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::680802512cc69d11e41287e55960087d
https://pubmed.ncbi.nlm.nih.gov/23171336

Zobrazit plný text záznamu

Development of a HPLC method for the determination of losartan urinary metabolic ratio to be used for the determination of CYP2C9 hydroxylation phenotypes

Autor: Fernando De Andrés, Angélica Rocío Borbón Orjuela, Manuela Grazina, Pedro Dorado, Addrián Llerena, Adrián LLerena, Yadira Xitlalli Perez Paramo

Publikováno v: Drug metabolism and drug interactions. 27(4)

BACKGROUND Losartan is metabolized to losartan carboxylic acid (E-3174) by the polymorphic cytochrome CYP2C9. The aim of the study was to develop a high-performance liquid chromatographic (HPLC) method with fluorescence detection for simultaneously m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cbe66073c2a51b7646b288032f97b31
https://pubmed.ncbi.nlm.nih.gov/23093260

Zobrazit plný text záznamu

Pharmacogenetics in Latin American populations: regulatory aspects, application to herbal medicine, cardiovascular and psychiatric disorders

Autor: Fernando De Andrés, Angélica Rocío Borbón Orjuela, Manuela Grazina, TERESA CORONA, Pedro Dorado, Addrián Llerena, Adriana Ochoa, ROCIO ORTIZ-LOPEZ, Marisol López-López, Adrián LLerena, Idania Rodeiro Guerra, Eduardo Tarazona, René Delgado Hernández, Romina Rojas Ponce, Yadira Xitlalli Perez Paramo, NANCY MONROY-JARAMILLO, AUGUSTO ROJAS-MARTINEZ, Enrique Teran

Publikováno v: Drug Metabolism and Drug Interactions. 27

Meeting report of the "Second Symposium on Pharmacology of Cytochrome P450 and Transporters" organized by the Cuban Society of Pharmacology in collaboration with the European Society of Pharmacogenetics and Theranostics (ESPT) and the Ibero-American

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5f247cac4b13655fa781e2331b09e704
https://doi.org/10.1515/dmdi-2012-0006

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání