Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Angélica Olmo-Fontánez"'
Autor:
Fatai S. Oladunni, Jun-Gyu Park, Paula A. Pino, Olga Gonzalez, Anwari Akhter, Anna Allué-Guardia, Angélica Olmo-Fontánez, Shalini Gautam, Andreu Garcia-Vilanova, Chengjin Ye, Kevin Chiem, Colwyn Headley, Varun Dwivedi, Laura M. Parodi, Kendra J. Alfson, Hilary M. Staples, Alyssa Schami, Juan I. Garcia, Alison Whigham, Roy Neal Platt, Michal Gazi, Jesse Martinez, Colin Chuba, Stephanie Earley, Oscar H. Rodriguez, Stephanie Davis Mdaki, Katrina N. Kavelish, Renee Escalona, Cory R. A. Hallam, Corbett Christie, Jean L. Patterson, Tim J. C. Anderson, Ricardo Carrion, Edward J. Dick, Shannan Hall-Ursone, Larry S. Schlesinger, Xavier Alvarez, Deepak Kaushal, Luis D. Giavedoni, Joanne Turner, Luis Martinez-Sobrido, Jordi B. Torrelles
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Here, the authors characterize tissue-level SARS-CoV-2 infection and pathogenesis in transgenic mice expressing human angiotensin converting enzyme 2 (hACE2) by the human cytokeratin 18 promoter (K18-hACE2) and show that infection induces lethality,
Externí odkaz:
https://doaj.org/article/36d6d32972464a4aafa1c9bc19844493
Autor:
Colwyn A. Headley, Shalini Gautam, Angelica Olmo‐Fontanez, Andreu Garcia‐Vilanova, Varun Dwivedi, Alyssa Schami, Susan Weintraub, Philip S. Tsao, Jordi B. Torrelles, Joanne Turner
Publikováno v:
Advanced Science, Vol 11, Iss 36, Pp n/a-n/a (2024)
Abstract Tuberculosis (TB), caused by Mycobacterium tuberculosis (M.tb), is a major global health concern, particularly affecting those with weakened immune systems, including the elderly. CD4+ T cell response is crucial for immunity against M.tb, bu
Externí odkaz:
https://doaj.org/article/0dd086a82df94a179d0e656b797beb92
Autor:
Robert E. Merrit, Jordi B. Torrelles, Andreu Garcia-Vilanova, Juan I. Moliva, Susan T. Weintraub, Larry S. Schlesinger, Angélica Olmo-Fontánez, Diego Maselli Caceres, Yufeng Wang, Jay I. Peters, Harjinder Singh, Anna Allué-Guardia, Joanne Turner
The elderly population is at increased risk of acute and chronic respiratory infections and other pulmonary diseases, and it is estimated that this population will double in the next 30 years. Biochemical changes in the lung alveolar mucosa and lung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa56134839aa2ed38a204e31ce41ac2f
https://doi.org/10.1101/2021.09.14.460375
https://doi.org/10.1101/2021.09.14.460375
Autor:
Larry S. Schlesinger, Angélica Olmo-Fontánez, Andreu Garcia-Vilanova, Jordi B. Torrelles, Yufeng Wang, Joanne Turner, Jay I. Peters, Anna Allué-Guardia, Diego J. Maselli
Tuberculosis (TB) infection, caused by the airborne pathogen Mycobacterium tuberculosis (M.tb), resulted in almost 1.4 million deaths in 2019 and the number of deaths is predicted to increase by 20% over the next 5 years due to the COVID-19 pandemic.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82c1f4f5304cd399a42cae1b150bd211
https://doi.org/10.1101/2021.09.08.459334
https://doi.org/10.1101/2021.09.08.459334
Autor:
Mark D. Wewers, Sabeen Sidiki, Holden V. Kelley, Jesus Arcos, Angélica Olmo-Fontánez, Julia M. Scordo, Anwari Akhter, Jordi B. Torrelles
Publikováno v:
Mucosal immunology
Mycobacterium tuberculosis (M.tb) is deposited into the alveolus where it first encounters the alveolar lining fluid (ALF) prior contacts host cells. We demonstrated that M.tb-exposure to human ALF alters its cell surface, driving better M.tb infecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d32d67754cf429b4aeca2a8b776c37
https://doi.org/10.1038/s41385-019-0156-2
https://doi.org/10.1038/s41385-019-0156-2
Autor:
Angélica Olmo-Fontánez, Andreu Garcia-Vilanova, Larry S. Schlesinger, Jay I. Peters, Jordi B. Torrelles, Julia M. Scordo, Daniel L. Clemens, Diego J. Maselli, Blanca I. Restrepo, Joanne Turner
The elderly population is at significant risk of developing respiratory diseases, including tuberculosis (TB) caused by the airborne Mycobacterium tuberculosis (M.tb). Once M.tb reaches the alveolar space, it contacts alveolar lining fluid (ALF) whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6a9aa1fd268ef399ed43c8d277c32fe
https://doi.org/10.1101/2021.05.12.443884
https://doi.org/10.1101/2021.05.12.443884
Autor:
Justin Ferdin, Vida L. Hodara, Dhiraj Kumar Singh, Shalini Gautam, Shabaana A. Khader, Shannan Hall-Ursone, Shashank Ganatra, Yenny Goez-Gazi, Tae-Hyung Lee, Benjamin Klaffke, Riti Sharan, Elizabeth Clemmons, Cynthia Alvarez, Olga Gonzalez, Christopher H. Chen, Kathleen M. Brasky, Laura M. Parodi, Kendra J. Alfson, Rajesh Thippeshappa, Alyssa Schami, Joanne Turner, Richard Copin, Andra K. Voges, Angélica Olmo-Fontánez, Makedonka Mitreva, Michal Gazi, Amanda Mannino, Patrice A. Frost, Ruby Escobedo, Alyssa Blakley, Deepak Kaushal, Edward J. Dick, Julia M. Scordo, Dharani Ajithdoss, John Dutton, Journey Cole, Hilary M. Staples, Christos A. Kyratsous, Priscilla Escareno, Luis D. Giavedoni, Ricardo Carrion, Bruce A. Rosa, Maya Gough, Luis Martinez-Sobrido, Mushtaq Ahmed, Bindu Singh, Roy N. Platt, Cory R. A. Hallam, Ken Sayers, Jessica Callery, Jordi B. Torrelles, Adelekan Oyejide, Jean L. Patterson, Andreu G. Vilanova, Carmen Bartley, Tim J. Anderson, Xavier Alvarez, Anna Goodroe, Larry S. Schlesinger, Corinna N. Ross, Alina Baum, Ayan Chatterjee
Publikováno v:
Nature Microbiology
Non-human primate models will expedite therapeutics and vaccines for coronavirus disease 2019 (COVID-19) to clinical trials. Here, we compare acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in young and old rhesus macaque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df631a7f20a4df6f6be2e3ef120b4b43
Publikováno v:
Advances in Host-Directed Therapies Against Tuberculosis ISBN: 9783030569044
Tuberculosis (TB) disease is caused by the intracellular pathogen Mycobacterium tuberculosis (M.tb), and currently represents a severe threat to global public health. After M.tb infection, there is a broad spectrum of potential outcomes leading to ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca1296129523b6d3dcacc5064f5341e4
https://doi.org/10.1007/978-3-030-56905-1_16
https://doi.org/10.1007/978-3-030-56905-1_16
Autor:
Andreu Garcia-Vilanova, Corbett Christie, Edward J. Dick, Jordi B. Torrelles, Hilary M. Staples, Kendra J. Alfson, Luis D. Giavedoni, Jun-Gyu Park, Tim J. Anderson, Kevin Chiem, Olga Gonzalez, Juan Ignacio García, Larry S. Schlesinger, Laura M. Parodi, Jean L. Patterson, Varun Dwivedi, Deepak Kaushal, Shannan Hall-Ursone, Colin Chuba, Ricardo Carrion, Chengjin Ye, Katrina N. Kavelish, Angélica Olmo-Fontánez, Stephanie Earley, Luis Martinez-Sobrido, Xavier Alvarez, Cory R. A. Hallam, Stephanie Davis Mdaki, Anna Allué-Guardia, Roy N. Platt, Renee Escalona, Paula A. Pino, Alyssa Schami, Colwyn A. Headley, Michal Gazi, Jesse Martinez, Shalini Gautam, Oscar H. Rodriguez, Fatai S. Oladunni, Joanne Turner, Alison Whigham, Anwari Akhter
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Vaccine and antiviral development against SARS-CoV-2 infection or COVID-19 disease would benefit from validated small animal models. Here, we show that transgenic mice expressing human angiotensin-converting enzyme 2 (hACE2) by the human cytokeratin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::123ec88794e140f131b6b71d51a806a8
https://doi.org/10.1038/s41467-020-19891-7
https://doi.org/10.1038/s41467-020-19891-7
Autor:
Shannan Hall-Ursone, Luis D. Giavedoni, Jun-Gyu Park, Anwari Akhter, Olga Gonzalez, Deepak Kaushal, Colin Chuba, Stephanie Earley, Colwyn A. Headley, Anna Allué-Guardia, Andreu Garcia-Vilanova, Alyssa Schami, Katrina N. Kavelish, Luis Martinez-Sobrido, Michal Gazi, Edward J. Dick, Jesse Martinez, Stephanie Davis Mdaki, Chengjin Ye, Cory R. A. Hallam, Jean L. Patterson, Fatai S. Oladunni, Joanne Turner, Tim J. Anderson, Kevin Chiem, Paula Pino Tamayo, Xavier Alvarez, Laura M. Parodi, Kendra J. Alfson, Jordi B. Torrelles, Roy N. Platt, Renee Escalona, Hilary M. Staples, Juan Ignacio García, Alison Whigham, Larry S. Schlesinger, Shalini Gautam, Angélica Olmo-Fontánez, Oscar H. Rodriguez, Varun Dwivedi, Ricardo Carrion, Corbett Christie
Vaccine and antiviral development against SARS-CoV-2 infection or COVID-19 disease currently lacks a validated small animal model. Here, we show that transgenic mice expressing human angiotensin converting enzyme 2 (hACE2) by the human cytokeratin 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa50cf7872db4bc56d6bc609bb2581ec
https://doi.org/10.1101/2020.07.18.210179
https://doi.org/10.1101/2020.07.18.210179